Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit

Gulay ILKHAN; Hakan CELİKHİSAR

doi:https://doi.org/10.28982/josam.842587

Makale detayları

Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit

Yazarlar:

Gulay ILKHAN | Hakan CELİKHİSAR

Yayıncı:

Fatih BAŞAK

Ana Başlıklar:

Hastalıklar

Dergi:

Journal of Surgery and Medicine 2021 Vol.5 Issue 1, pp.31-35

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000499182

Sıklık:

Aylık

eISSN:

2602-2079

DOI:

https://doi.org/10.28982/josam.842587

Özet:

 

Background/Aim: Thrombocytopenia is a common hematological abnormality among patients in the intensive care unit (ICU). The development of thrombocytopenia in the ICU usually indicates severe organ system dysfunction rather than a primary hematological disorder. We aimed to determine the incidence, causes, and clinical results of thrombocytopenia in patients followed up in ICU. 
Methods: In this retrospective cohort study, 165 patients who were followed up in the ICU with thrombocyte counts below 150,000 /uL were included and causes of thrombocytopenia, along with its effects on mortality and intensive care stay were investigated. 
Results: Thrombocytopenia was determined in 30.1% of the patients in the ICU. The cause of thrombocytopenia was sepsis in 33 (20.0%) of the patients and disseminated intravascular coagulation (DIC) in 20 (12.1%) patients. During the study period, 115 (69.7%) of 165 thrombocytopenic patients and 173 (45.1%) of 383 patients without thrombocytopenia died. Mortality was significantly higher in patients with thrombocytopenia. Mortality significantly increased when platelet count decreased, even with similar APACHE II scores. 
Conclusion: The most common causes of thrombocytopenia in the ICU were sepsis and DIC. Thrombocytopenia is common in the ICU and increases mortality rates.

Makale detayları

Thrombocytopenia and its effect on mortality and morbidity in the intensive care unit

Yazarlar: Gulay ILKHAN | Hakan CELİKHİSAR

Yayıncı: Fatih BAŞAK

Ana Başlıklar: Hastalıklar

Dergi: Journal of Surgery and Medicine 2021 Vol.5 Issue 1, pp.31-35

Belge Tipi: Makale

Yayın Tarihi: 12/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000499182

Sıklık: Aylık

eISSN: 2602-2079

DOI: https://doi.org/10.28982/josam.842587

Sayı

Yazarlar:

Gulay ILKHAN | Hakan CELİKHİSAR

Yayıncı:

Fatih BAŞAK

Ana Başlıklar:

Hastalıklar

Dergi:

Journal of Surgery and Medicine 2021 Vol.5 Issue 1, pp.31-35

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000499182

Sıklık:

Aylık

eISSN:

2602-2079

DOI:

https://doi.org/10.28982/josam.842587