BUDESONIDE SELF-NANOEMULSION FORMULATION AS AN ORAL DRUG DELIVERY SYSTEM: PREPARATION, CHARACTERIZATION AND CYTOTOXICITY STUDIES

Burcu Mesut; Seyma Hande Tekarslan Sahin; Yildiz Ozsoy

doi:https://doi.org/10.17261/Pressacademia.2017.569

Makale detayları

BUDESONIDE SELF-NANOEMULSION FORMULATION AS AN ORAL DRUG DELIVERY SYSTEM: PREPARATION, CHARACTERIZATION AND CYTOTOXICITY STUDIES

Yazarlar:

Burcu Mesut | Seyma Hande Tekarslan Sahin | Yildiz Ozsoy

Yayıncı:

PressAcademia

Ana Başlıklar:

Sosyal Bilimler

Dergi:

PressAcademia Procedia 2017 Vol.5 Issue 1, pp.41-46

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000776527

Sıklık:

Üç Yıllık

eISSN:

2459-0762

DOI:

https://doi.org/10.17261/Pressacademia.2017.569

Özet:

 


Lipophilic
drugs which are poorly water soluble need specific applications like lipid
based delivery systems to increase their oral absorption across
gastrointestinal tract. Selfnanoemulsifying drug delivery systems are Lipid
Based Drug Delivery systems (SNEEDs) and are consists of an isotropic mixture
of oil, surfactant(s) and co-surfactant. This drug delivery systems are
prepared at room temperature with gentle stirring process without using any
other component or heating process and become nanoemulsion form upon gentle
agitation in aqueous phase.  SNEDDs have
many advantages such as they can be produced easily and they are affected less
from other outside factors, its scaleup process is easy, unaffected by lipid
digestion, carry and protect peptides which can be enzymatically hydrolyzed.
The aim of this study was to increase solubility of Budesonide by using new
Snedds formulation approach. 





 


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Makale detayları

BUDESONIDE SELF-NANOEMULSION FORMULATION AS AN ORAL DRUG DELIVERY SYSTEM: PREPARATION, CHARACTERIZATION AND CYTOTOXICITY STUDIES

Yazarlar: Burcu Mesut | Seyma Hande Tekarslan Sahin | Yildiz Ozsoy

Yayıncı: PressAcademia

Ana Başlıklar: Sosyal Bilimler

Dergi: PressAcademia Procedia 2017 Vol.5 Issue 1, pp.41-46

Belge Tipi: Makale

Yayın Tarihi: 6/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000776527

Sıklık: Üç Yıllık

eISSN: 2459-0762

DOI: https://doi.org/10.17261/Pressacademia.2017.569

Sayı

Yazarlar:

Burcu Mesut | Seyma Hande Tekarslan Sahin | Yildiz Ozsoy

Yayıncı:

PressAcademia

Ana Başlıklar:

Sosyal Bilimler

Dergi:

PressAcademia Procedia 2017 Vol.5 Issue 1, pp.41-46

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000776527

Sıklık:

Üç Yıllık

eISSN:

2459-0762

DOI:

https://doi.org/10.17261/Pressacademia.2017.569