Evaluation of Relationship Between C-Reactive Protein, Leukocyte Count and Platelet Indices in Dogs with Leukocytosis

Serkan İrfan Köse; Alper Ertürk; Gökhan Uyanık; Aliye Sağkan Öztürk

Makale detayları

Evaluation of Relationship Between C-Reactive Protein, Leukocyte Count and Platelet Indices in Dogs with Leukocytosis

Yazarlar:

Serkan İrfan Köse | Alper Ertürk | Gökhan Uyanık | Aliye Sağkan Öztürk

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Hekimlik | Veteriner Tanı ve Teşhis

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 3, pp.270-279

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001324779

pISSN:

1308-1594

Anahtar kelimeler:

Özet:

 A complete blood count and acute-phase protein analyses are the laboratory tests that are used in veterinary medicine practice. Leukocytes, also known as white blood cells WBCs, are the primary biological components of inflammatory and immunological responses. C-reactive protein CRP is a powerful predictor of inflammation andor infection in veterinary medicine. Starting at that point, the investigation of the alterations and relationship between WBC count, platelet indices, and blood serum CRP levels in dogs with leukocytosis was the aim of this study. A total of 135 bloodwork records, from January 2018 to December 2022, of dogs were analyzed. The inflammatory panel of complete blood count data, including WBC, PLT, MPV, PDW, PCT, and MPVPLT, and CRP levels in blood serum chemistry analyses were investigated. The inflammatory panel of complete blood count data was categorized according to CRP levels in blood serum chemistry analyses. There was no significant difference in platelet indices according to the blood serum levels of CRP in the dogs bloodwork records. The WBC count in dogs with an equal or above 10 mgdL CRP level was significantly higher than the other levels of CRP. A moderately positive correlation was detected between CRP and WBC in the bloodwork of all dogs, undivided according to inflammatory status, and of dogs with an inflammatory status. Consequently, in veterinary clinical practice, C-reactive protein measures in dogs may be more applicable in cases where an important rise in WBC over the cut-off value is observed in the complete blood count, commonly used to diagnose inflammatory or infectious status.

 A complete blood count and acute-phase protein analyses are the laboratory tests that are used in veterinary medicine practice. Leukocytes, also known as white blood cells WBCs, are the primary biological components of inflammatory and immunological responses. C-reactive protein CRP is a powerful predictor of inflammation andor infection in veterinary medicine. Starting at that point, the investigation of the alterations and relationship between WBC count, platelet indices, and blood serum CRP levels in dogs with leukocytosis was the aim of this study. A total of 135 bloodwork records, from January 2018 to December 2022, of dogs were analyzed. The inflammatory panel of complete blood count data, including WBC, PLT, MPV, PDW, PCT, and MPVPLT, and CRP levels in blood serum chemistry analyses were investigated. The inflammatory panel of complete blood count data was categorized according to CRP levels in blood serum chemistry analyses. There was no significant difference in platelet indices according to the blood serum levels of CRP in the dogs bloodwork records. The WBC count in dogs with an equal or above 10 mgdL CRP level was significantly higher than the other levels of CRP. A moderately positive correlation was detected between CRP and WBC in the bloodwork of all dogs, undivided according to inflammatory status, and of dogs with an inflammatory status. Consequently, in veterinary clinical practice, C-reactive protein measures in dogs may be more applicable in cases where an important rise in WBC over the cut-off value is observed in the complete blood count, commonly used to diagnose inflammatory or infectious status.

 A complete blood count and acute-phase protein analyses are the laboratory tests that are used in veterinary medicine practice. Leukocytes, also known as white blood cells WBCs, are the primary biological components of inflammatory and immunological responses. C-reactive protein CRP is a powerful predictor of inflammation andor infection in veterinary medicine. Starting at that point, the investigation of the alterations and relationship between WBC count, platelet indices, and blood serum CRP levels in dogs with leukocytosis was the aim of this study. A total of 135 bloodwork records, from January 2018 to December 2022, of dogs were analyzed. The inflammatory panel of complete blood count data, including WBC, PLT, MPV, PDW, PCT, and MPVPLT, and CRP levels in blood serum chemistry analyses were investigated. The inflammatory panel of complete blood count data was categorized according to CRP levels in blood serum chemistry analyses. There was no significant difference in platelet indices according to the blood serum levels of CRP in the dogs bloodwork records. The WBC count in dogs with an equal or above 10 mgdL CRP level was significantly higher than the other levels of CRP. A moderately positive correlation was detected between CRP and WBC in the bloodwork of all dogs, undivided according to inflammatory status, and of dogs with an inflammatory status. Consequently, in veterinary clinical practice, C-reactive protein measures in dogs may be more applicable in cases where an important rise in WBC over the cut-off value is observed in the complete blood count, commonly used to diagnose inflammatory or infectious status.

 Tam kan sayımı ve akut faz protein analizleri veteriner hekimlik uygulamalarında kullanılan laboratuvar testleridir. Beyaz kan hücreleri WBCler olarak da bilinen lökositler, enflamatuar ve immünolojik yanıtların birincil biyolojik bileşenleridir. C-reaktif protein CRP veteriner hekimlikte enflamasyon veveya enfeksiyonun güçlü bir belirleyicisidir. Bu noktadan hareketle, lökositozlu köpeklerde WBC sayısı, trombosit indeksleri ve kan serumu CRP seviyeleri arasındaki değişikliklerin ve ilişkinin araştırılması bu çalışmanın amacını oluşturmuştur. Ocak 2018den Aralık 2022ye kadar köpeklere ait toplam 135 kan tahlili kaydı analiz edilmiştir. WBC, PLT, MPV, PDW, PCT ve MPVPLT dahil olmak üzere tam kan sayımı verilerinin enflamatuar paneli ve kan serumu kimyası analizlerinde CRP seviyeleri araştırıldı. Tam kan sayımı verilerinin enflamatuar paneli, kan serumu kimyası analizlerindeki CRP düzeylerine göre kategorize edildi. Köpeklerin kan serumu CRP seviyelerine göre trombosit indekslerinde anlamlı bir fark bulunmamıştır. CRP seviyesi 10 mgdL ve üzerinde olan köpeklerde WBC sayısı diğer CRP seviyelerine göre anlamlı derecede yüksekti. Yangı durumuna göre ayrılmamış tüm köpeklerin ve yangı durumu olan köpeklerin kan tahlillerinde CRP ve WBC arasında orta düzeyde pozitif bir korelasyon tespit edilmiştir. Sonuç olarak, veteriner klinik uygulamalarında, köpeklerde C-reaktif protein ölçümleri, enflamatuar ya da enfeksiyöz durumu teşhis etmek için yaygın olarak kullanılan tam kan sayımında WBCde kesme değerinin üzerinde önemli bir artış gözlendiği durumlarda daha uygulanabilir olabilir.

Makale detayları

Evaluation of Relationship Between C-Reactive Protein, Leukocyte Count and Platelet Indices in Dogs with Leukocytosis

Yazarlar:

Serkan İrfan Köse | Alper Ertürk | Gökhan Uyanık | Aliye Sağkan Öztürk

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Hekimlik | Veteriner Tanı ve Teşhis

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 3, pp.270-279

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001324779

pISSN:

1308-1594

Dog

C-reactive protein

Complete Blood Count

LeukocytosisKöpek

C-reaktif protein

Tam Kan Sayımı

Lökositoz

Sayı

Makale detayları

Yazarlar: Serkan İrfan Köse | Alper Ertürk | Gökhan Uyanık | Aliye Sağkan Öztürk

Yayıncı: Afyon Kocatepe University

Ana Başlıklar: Veteriner Hekimlik | Veteriner Tanı ve Teşhis

Dergi: Kocatepe Veteriner Dergisi Vol.17 Issue 3, pp.270-279

Belge Tipi: Makale

Yayın Tarihi: 9/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001324779

pISSN: 1308-1594

Sayı

Yazarlar:

Serkan İrfan Köse | Alper Ertürk | Gökhan Uyanık | Aliye Sağkan Öztürk

Yayıncı:

Afyon Kocatepe University

Ana Başlıklar:

Veteriner Hekimlik | Veteriner Tanı ve Teşhis

Dergi:

Kocatepe Veteriner Dergisi Vol.17 Issue 3, pp.270-279

Belge Tipi:

Makale

Yayın Tarihi:

9/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001324779

pISSN:

1308-1594