A decade of SGLT2 inhibitors in cardiovascular science: a bibliometric review

Ahmet Yılmaz

Makale detayları

A decade of SGLT2 inhibitors in cardiovascular science: a bibliometric review

Yazarlar:

Ahmet Yılmaz

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Journal of Health Sciences and Medicine Vol.8 Issue 3, pp.461-468

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349472

pISSN:

2636-8579

Anahtar kelimeler:

Özet:

 Aims: Sodium-glucose cotransporter 2 SGLT2 inhibitors have gained significant attention in cardiovascular science due to their cardioprotective and Reno protective effects beyond glucose control. Over the past decade, research in this field has expanded rapidly. This study aims to conduct a bibliometric analysis of global research trends on SGLT2 inhibitors in cardiovascular diseases from 2014 to 2024, evaluating publication output, citation impact, influential contributors, keyword trends, and international collaboration networks. Methods: A bibliometric analysis was performed using the Web of Science WoS Core Collection database, focusing on articles published between January 1, 2014, and December 31, 2024, within the cardiac cardiovascular system category. VOSviewer software was utilized to visualize author collaborations, institutional affiliations, keyword co-occurrence, and citation distributions. Results: A total of 1,271 articles were analyzed. Research output has increased significantly, particularly after 2020, aligning with key clinical trials on SGLT2 inhibitors. The most prolific journals included Cardiovascular Diabetology, Journal of the American College of Cardiology, and European Journal of Heart Failure. Leading institutions such as Harvard Medical School, University of Toronto, and University of Groningen were identified as major contributors. Citation analysis highlighted high-impact studies on SGLT2 inhibitors cardiovascular and renal benefits. Keyword co-occurrence analysis showed that heart failure, diabetes mellitus, and renal protection were dominant themes. The United States, Germany, and China emerged as major players in global collaborations, shaping the research landscape. Conclusion: The bibliometric findings suggest that research on SGLT2 inhibitors in cardiovascular diseases is rapidly evolving, with increasing global contributions and high-impact publications shaping clinical applications. Future studies should focus on long-term cardiovascular and renal outcomes, mechanistic insights, and comparative effectiveness research to further establish SGLT2 inhibitors role in cardiovascular medicine.

 Aims: Sodium-glucose cotransporter 2 SGLT2 inhibitors have gained significant attention in cardiovascular science due to their cardioprotective and Reno protective effects beyond glucose control. Over the past decade, research in this field has expanded rapidly. This study aims to conduct a bibliometric analysis of global research trends on SGLT2 inhibitors in cardiovascular diseases from 2014 to 2024, evaluating publication output, citation impact, influential contributors, keyword trends, and international collaboration networks. Methods: A bibliometric analysis was performed using the Web of Science WoS Core Collection database, focusing on articles published between January 1, 2014, and December 31, 2024, within the cardiac cardiovascular system category. VOSviewer software was utilized to visualize author collaborations, institutional affiliations, keyword co-occurrence, and citation distributions. Results: A total of 1,271 articles were analyzed. Research output has increased significantly, particularly after 2020, aligning with key clinical trials on SGLT2 inhibitors. The most prolific journals included Cardiovascular Diabetology, Journal of the American College of Cardiology, and European Journal of Heart Failure. Leading institutions such as Harvard Medical School, University of Toronto, and University of Groningen were identified as major contributors. Citation analysis highlighted high-impact studies on SGLT2 inhibitors cardiovascular and renal benefits. Keyword co-occurrence analysis showed that heart failure, diabetes mellitus, and renal protection were dominant themes. The United States, Germany, and China emerged as major players in global collaborations, shaping the research landscape. Conclusion: The bibliometric findings suggest that research on SGLT2 inhibitors in cardiovascular diseases is rapidly evolving, with increasing global contributions and high-impact publications shaping clinical applications. Future studies should focus on long-term cardiovascular and renal outcomes, mechanistic insights, and comparative effectiveness research to further establish SGLT2 inhibitors role in cardiovascular medicine.

 Aims: Sodium-glucose cotransporter 2 SGLT2 inhibitors have gained significant attention in cardiovascular science due to their cardioprotective and Reno protective effects beyond glucose control. Over the past decade, research in this field has expanded rapidly. This study aims to conduct a bibliometric analysis of global research trends on SGLT2 inhibitors in cardiovascular diseases from 2014 to 2024, evaluating publication output, citation impact, influential contributors, keyword trends, and international collaboration networks. Methods: A bibliometric analysis was performed using the Web of Science WoS Core Collection database, focusing on articles published between January 1, 2014, and December 31, 2024, within the cardiac cardiovascular system category. VOSviewer software was utilized to visualize author collaborations, institutional affiliations, keyword co-occurrence, and citation distributions. Results: A total of 1,271 articles were analyzed. Research output has increased significantly, particularly after 2020, aligning with key clinical trials on SGLT2 inhibitors. The most prolific journals included Cardiovascular Diabetology, Journal of the American College of Cardiology, and European Journal of Heart Failure. Leading institutions such as Harvard Medical School, University of Toronto, and University of Groningen were identified as major contributors. Citation analysis highlighted high-impact studies on SGLT2 inhibitors cardiovascular and renal benefits. Keyword co-occurrence analysis showed that heart failure, diabetes mellitus, and renal protection were dominant themes. The United States, Germany, and China emerged as major players in global collaborations, shaping the research landscape. Conclusion: The bibliometric findings suggest that research on SGLT2 inhibitors in cardiovascular diseases is rapidly evolving, with increasing global contributions and high-impact publications shaping clinical applications. Future studies should focus on long-term cardiovascular and renal outcomes, mechanistic insights, and comparative effectiveness research to further establish SGLT2 inhibitors role in cardiovascular medicine.

 Amaç: Sodyum-glukoz kotransportör 2 SGLT2 inhibitörleri, yalnızca glukoz kontrolünün ötesinde sundukları kardiyoprotektif ve renoprotektif etkiler nedeniyle kardiyovasküler bilim alanında önemli bir ilgi görmüştür. Son on yılda bu alandaki araştırmalar hızlı bir şekilde artmıştır. Bu çalışma, 20142024 yılları arasında SGLT2 inhibitörlerinin kardiyovasküler hastalıklardaki rolüne ilişkin küresel araştırma eğilimlerini değerlendiren bir bibliyometrik analiz yapmayı; yayın çıktıları, atıf etkisi, etkili araştırmacılar, anahtar kelime eğilimleri ve uluslararası iş birliği ağlarını incelemeyi amaçlamaktadır. Yöntemler: Bibliyometrik analiz, Web of Science WoS Core Collection veritabanı kullanılarak gerçekleştirilmiş olup, 1 Ocak 2014 ile 31 Aralık 2024 tarihleri arasında Cardiac Cardiovascular System kategorisinde yayımlanan makalelere odaklanılmıştır. Yazar iş birlikleri, kurumsal bağlantılar, anahtar kelime eşgörünümleri ve atıf dağılımları VOSviewer yazılımı ile görselleştirilmiştir. Bulgular: Toplam 1.271 makale analiz edilmiştir. Araştırma çıktılarında özellikle 2020 sonrası belirgin bir artış gözlemlenmiş olup, bu durum SGLT2 inhibitörleriyle ilgili önemli klinik çalışmalarla örtüşmektedir. En üretken dergiler arasında Cardiovascular Diabetology, Journal of the American College of Cardiology ve European Journal of Heart Failure yer almıştır. Harvard Tıp Fakültesi, Toronto Üniversitesi ve Groningen Üniversitesi gibi önde gelen kurumlar başlıca katkı sağlayıcılar olarak öne çıkmıştır. Atıf analizi, SGLT2 inhibitörlerinin kardiyovasküler ve böbrek faydalarına odaklanan yüksek etkili çalışmaları ön plana çıkarmıştır. Anahtar kelime eşgörünüm analizinde kalp yetmezliği, diabetes mellitus ve böbrek koruması baskın temalar olarak öne çıkmıştır. Amerika Birleşik Devletleri, Almanya ve Çin, küresel iş birliği ağı içinde önemli aktörler olarak belirlenmiş ve araştırma alanının şekillenmesinde etkili olmuştur. Sonuç: Bibliyometrik bulgular, SGLT2 inhibitörlerinin kardiyovasküler hastalıklardaki araştırma alanının hızla geliştiğini, küresel katkıların arttığını ve klinik uygulamaları şekillendiren yüksek etkili yayınların ortaya çıktığını göstermektedir. Gelecekteki çalışmalar, uzun vadeli kardiyovasküler ve renal sonuçlara, mekanistik açıklamalara ve karşılaştırmalı etkinlik araştırmalarına odaklanmalıdır; böylece SGLT2 inhibitörlerinin kardiyovasküler tıptaki yeri daha sağlam bir şekilde ortaya konulabilir.

Makale detayları

A decade of SGLT2 inhibitors in cardiovascular science: a bibliometric review

Yazarlar:

Ahmet Yılmaz

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Journal of Health Sciences and Medicine Vol.8 Issue 3, pp.461-468

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349472

pISSN:

2636-8579

SGLT2 inhibitors

cardiovascular diseases

heart failure

bibliometric analysis

citation impactSGLT2 inhibitörleri

kardiyovasküler hastalıklar

kalp yetmezliği

bibliyometrik analiz

atıf etkisi

Sayı

Makale detayları

Yazarlar: Ahmet Yılmaz

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Kardiyoloji

Dergi: Journal of Health Sciences and Medicine Vol.8 Issue 3, pp.461-468

Belge Tipi: Makale

Yayın Tarihi: 5/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001349472

pISSN: 2636-8579

Sayı

Yazarlar:

Ahmet Yılmaz

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Kardiyoloji

Dergi:

Journal of Health Sciences and Medicine Vol.8 Issue 3, pp.461-468

Belge Tipi:

Makale

Yayın Tarihi:

5/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001349472

pISSN:

2636-8579