The Effect Of Serotonın Reuptake Inhıbıtor Use On Restless Legs Syndrome In Chıldren

Derya Yavuz Demiray; Seda Aybüke Sarı; Mehmet Erdem

Makale detayları

The Effect Of Serotonın Reuptake Inhıbıtor Use On Restless Legs Syndrome In Chıldren

Yazarlar:

Derya Yavuz Demiray | Seda Aybüke Sarı | Mehmet Erdem

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Psikiyatri | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.110-116

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343465

pISSN:

2147-9607

Anahtar kelimeler:

Özet:

 Objective: This research intends to investigate the relationship between selective serotonin reuptake inhibitors SSRIs and the occurrence rate of Restless Legs Syndrome RLS among pediatric and adolescent populations diagnosed with depression andor anxiety disorders. Materials and Methods: This retrospective study examined patients between the ages of 10 and 17 who had been prescribed one of the following selective serotonin reuptake inhibitors SSRIs: fluoxetine, sertraline, or escitalopram. Exclusion criteria included patients with iron deficiency anemia, diabetes mellitus, renal disorders, spinal cord conditions, those receiving antihistaminic or antipsychotic medications, and individuals with other psychiatric or neurological disorders. The study meticulously recorded demographic information, medical histories, ferritin levels, vitamin B12 levels, and a family history of restless legs syndrome RLS. Furthermore, the severity of RLS was evaluated using a specific scale for patients diagnosed with the condition. Results: Among the 40 children analyzed, 10 developed RLS. The results indicated a potential link between SSRI use and the onset of RLS symptoms. No significant relationship was found between RLS and hemoglobin, ferritin, or vitamin B12 levels. Half of the RLS patients had a family history of RLS. Conclusion: The results indicate a possible association between the administration of SSRIs and the emergence of RLS in pediatric and adolescent populations. It is advisable to conduct additional studies with an expanded sample size.

 Objective: This research intends to investigate the relationship between selective serotonin reuptake inhibitors SSRIs and the occurrence rate of Restless Legs Syndrome RLS among pediatric and adolescent populations diagnosed with depression andor anxiety disorders. Materials and Methods: This retrospective study examined patients between the ages of 10 and 17 who had been prescribed one of the following selective serotonin reuptake inhibitors SSRIs: fluoxetine, sertraline, or escitalopram. Exclusion criteria included patients with iron deficiency anemia, diabetes mellitus, renal disorders, spinal cord conditions, those receiving antihistaminic or antipsychotic medications, and individuals with other psychiatric or neurological disorders. The study meticulously recorded demographic information, medical histories, ferritin levels, vitamin B12 levels, and a family history of restless legs syndrome RLS. Furthermore, the severity of RLS was evaluated using a specific scale for patients diagnosed with the condition. Results: Among the 40 children analyzed, 10 developed RLS. The results indicated a potential link between SSRI use and the onset of RLS symptoms. No significant relationship was found between RLS and hemoglobin, ferritin, or vitamin B12 levels. Half of the RLS patients had a family history of RLS. Conclusion: The results indicate a possible association between the administration of SSRIs and the emergence of RLS in pediatric and adolescent populations. It is advisable to conduct additional studies with an expanded sample size.

 Objective: This research intends to investigate the relationship between selective serotonin reuptake inhibitors SSRIs and the occurrence rate of Restless Legs Syndrome RLS among pediatric and adolescent populations diagnosed with depression andor anxiety disorders. Materials and Methods: This retrospective study examined patients between the ages of 10 and 17 who had been prescribed one of the following selective serotonin reuptake inhibitors SSRIs: fluoxetine, sertraline, or escitalopram. Exclusion criteria included patients with iron deficiency anemia, diabetes mellitus, renal disorders, spinal cord conditions, those receiving antihistaminic or antipsychotic medications, and individuals with other psychiatric or neurological disorders. The study meticulously recorded demographic information, medical histories, ferritin levels, vitamin B12 levels, and a family history of restless legs syndrome RLS. Furthermore, the severity of RLS was evaluated using a specific scale for patients diagnosed with the condition. Results: Among the 40 children analyzed, 10 developed RLS. The results indicated a potential link between SSRI use and the onset of RLS symptoms. No significant relationship was found between RLS and hemoglobin, ferritin, or vitamin B12 levels. Half of the RLS patients had a family history of RLS. Conclusion: The results indicate a possible association between the administration of SSRIs and the emergence of RLS in pediatric and adolescent populations. It is advisable to conduct additional studies with an expanded sample size.

 Amaç: Bu araştırma, seçici serotonin geri alım inhibitörleri SSRIlar ile depresyon veveya anksiyete bozuklukları tanısı alan çocuk ve ergen popülasyonlarında Huzursuz Bacak Sendromu HBS görülme oranı arasındaki ilişkiyi incelemeyi amaçlamaktadır. Gereç ve Yöntemler: Bu retrospektif çalışmada, fluoksetin, sertralin veya essitalopram gibi seçici serotonin geri alım inhibitörlerinden SSRIlar birini kullanmış 10-17 yaş arası hastalar incelenmiştir. Dışlama kriterleri arasında demir eksikliği anemisi, diyabet, böbrek hastalıkları, omurilik rahatsızlıkları, antihistaminik veya antipsikotik ilaç kullananlar ve diğer psikiyatrik ya da nörolojik bozukluklara sahip hastalar yer almıştır. Çalışmada, demografik bilgiler, tıbbi geçmiş, ferritin seviyeleri, vitamin B12 seviyeleri ve ailede huzursuz bacak sendromu HBS öyküsü kaydedilmiştir. Ayrıca, HBS tanısı konulan hastaların durumunun şiddeti HBS şiddet ölçeği ile değerlendirilmiştir. Bulgular: Analiz edilen 40 çocuk arasında 10unda HBS gelişmiştir. Sonuçlar, SSRI kullanımının HBS semptomlarının ortaya çıkışıyla potansiyel bir bağlantısı olabileceğini göstermiştir. HBS ile hemoglobin, ferritin veya vitamin B12 seviyeleri arasında anlamlı bir ilişki bulunmamıştır. HBS tanısı alan hastaların yarısında HBS aile öyküsü tespit edilmiştir. Sonuç: Sonuçlar, SSRI kullanımının çocuk ve ergen popülasyonlarında HBS gelişimi ile olası bir ilişkiyi işaret etmektedir. Daha geniş bir örneklem büyüklüğüyle ek çalışmalar yapılması tavsiye edilmektedir.

Makale detayları

The Effect Of Serotonın Reuptake Inhıbıtor Use On Restless Legs Syndrome In Chıldren

Yazarlar:

Derya Yavuz Demiray | Seda Aybüke Sarı | Mehmet Erdem

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Psikiyatri | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.110-116

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343465

pISSN:

2147-9607

Restless Legs Syndrome

Serotonin Reuptake Inhibitors

Children

Depression

Anxiety DisordersHuzursuz bacak sendromu

çocuklar

serotonin gerialım inhibitörleri

depresyon

anksiyete bozuklukları

Sayı

Makale detayları

Yazarlar: Derya Yavuz Demiray | Seda Aybüke Sarı | Mehmet Erdem

Yayıncı: Manisa Celal Bayar University

Ana Başlıklar: Psikiyatri | Nöroloji ve Nöromüsküler Hastalıklar

Dergi: Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.110-116

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001343465

pISSN: 2147-9607

Sayı

Yazarlar:

Derya Yavuz Demiray | Seda Aybüke Sarı | Mehmet Erdem

Yayıncı:

Manisa Celal Bayar University

Ana Başlıklar:

Psikiyatri | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi Vol.12 Issue 1, pp.110-116

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001343465

pISSN:

2147-9607