Proof-of-concept about the role of dietary agents in the  inhibition and prevention of carcinogenesis and  metastasis: Focus on animal model studies

N.A.

Makale detayları

Proof-of-concept about the role of dietary agents in the inhibition and prevention of carcinogenesis and metastasis: Focus on animal model studies

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.436-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339624

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The field of nutrigenomics has gained considerable limelight and interdisciplinary researchers have started to realize its significance as a goldmine for the discovery of pathways that are important as dietary targets. Emerging evidence has provided wealth of exciting proof-of-concept studies highlighting an important role in the elucidation of oncogenic signaling cascades that can be pharmacologically targeted by dietary agents, whole extracts and isolated compounds for the inhibitionprevention of carcinogenesis and metastasis. In this review, we have critically analyzed some of the mechanistic animal models studies which have rationally propelled the field in a frontward direction. We also provide an overview of the fruits-mediated anti-metastatic effects in metastasis models that highlight how nutrigenomics may be combined with pharmacological therapies for synergistic effects, potentially ushering a path towards precision nutrition for cancer.

 The field of nutrigenomics has gained considerable limelight and interdisciplinary researchers have started to realize its significance as a goldmine for the discovery of pathways that are important as dietary targets. Emerging evidence has provided wealth of exciting proof-of-concept studies highlighting an important role in the elucidation of oncogenic signaling cascades that can be pharmacologically targeted by dietary agents, whole extracts and isolated compounds for the inhibitionprevention of carcinogenesis and metastasis. In this review, we have critically analyzed some of the mechanistic animal models studies which have rationally propelled the field in a frontward direction. We also provide an overview of the fruits-mediated anti-metastatic effects in metastasis models that highlight how nutrigenomics may be combined with pharmacological therapies for synergistic effects, potentially ushering a path towards precision nutrition for cancer.

 The field of nutrigenomics has gained considerable limelight and interdisciplinary researchers have started to realize its significance as a goldmine for the discovery of pathways that are important as dietary targets. Emerging evidence has provided wealth of exciting proof-of-concept studies highlighting an important role in the elucidation of oncogenic signaling cascades that can be pharmacologically targeted by dietary agents, whole extracts and isolated compounds for the inhibitionprevention of carcinogenesis and metastasis. In this review, we have critically analyzed some of the mechanistic animal models studies which have rationally propelled the field in a frontward direction. We also provide an overview of the fruits-mediated anti-metastatic effects in metastasis models that highlight how nutrigenomics may be combined with pharmacological therapies for synergistic effects, potentially ushering a path towards precision nutrition for cancer.

 The field of nutrigenomics has gained considerable limelight and interdisciplinary researchers have started to realize its significance as a goldmine for the discovery of pathways that are important as dietary targets. Emerging evidence has provided wealth of exciting proof-of-concept studies highlighting an important role in the elucidation of oncogenic signaling cascades that can be pharmacologically targeted by dietary agents, whole extracts and isolated compounds for the inhibitionprevention of carcinogenesis and metastasis. In this review, we have critically analyzed some of the mechanistic animal models studies which have rationally propelled the field in a frontward direction. We also provide an overview of the fruits-mediated anti-metastatic effects in metastasis models that highlight how nutrigenomics may be combined with pharmacological therapies for synergistic effects, potentially ushering a path towards precision nutrition for cancer.

Makale detayları

Proof-of-concept about the role of dietary agents in the inhibition and prevention of carcinogenesis and metastasis: Focus on animal model studies

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.436-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339624

pISSN:

2630-6344

Cancer

Nutrigenomics

Metastasis

Cell signaling

Apoptosis

Sayı

Makale detayları

Proof-of-concept about the role of dietary agents in the inhibition and prevention of carcinogenesis and metastasis: Focus on animal model studies

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacology and Pharmaceutical Sciences (Other)

Dergi: Journal of Research in Pharmacy Vol.29 Issue 1, pp.436-444

Belge Tipi: Makale

Yayın Tarihi: 3/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001339624

pISSN: 2630-6344

Cancer

Nutrigenomics

Metastasis

Cell signaling

Apoptosis

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.29 Issue 1, pp.436-444

Belge Tipi:

Makale

Yayın Tarihi:

3/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001339624

pISSN:

2630-6344