Investigation of West Nile virus among healthy blood donors in the western part of Turkey

Servet ULUER BİÇEROĞLU; Ersin KARATAYLI; Arzu BAYRAM; Ajda TURHAN; Aysu DEĞİRMENCİ; Yeşim AYDINOK; Abdurrahman Mithat BOZDAYI; Şaziye Rüçhan SERTÖZ

Makale detayları

Investigation of West Nile virus among healthy blood donors in the western part of Turkey

Yazarlar:

Servet ULUER BİÇEROĞLU | Ersin KARATAYLI | Arzu BAYRAM | Ajda TURHAN | Aysu DEĞİRMENCİ | Yeşim AYDINOK | Abdurrahman Mithat BOZDAYI | Şaziye Rüçhan SERTÖZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.84-88

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752865

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

The West Nile virus (WNV) is a mosquito-borne flavivirus causing different forms of infection among humans, varying from asymptomatic illness to fetal central nervous system infection. Turkey lies within an endemic region for WNV. Transfusion of infected blood products is another well-documented major route of transmission. The aim of our study was to investigate the presence of WNV viremia among a healthy donor population from the western part of the country.   Materials and methods: A total of 438 healthy volunteer blood donors were included in the study. The presence of WNV RNA was investigated by quantitative real-time reverse-transcriptase polymerase chain reaction (qRT-PCR) and anti-WNV IgG was detected by a commercial ELISA test.   Results: Ages of volunteer donors were 18-62 years (mean: 34.7) and 34 (7.76%) were women. All samples were negative for WNV RNA by qRT-PCR. Eleven (2.51%) samples, 1 of which was borderline, were positive for anti-WNV IgG. All positive samples were from the western part of the country and 9 of them were from İzmir.   Conclusion: Although all donor samples were negative for WNV RNA by qRT-PCR, the risk of WNV transmission via blood products should not be ignored in endemic regions.

 

The West Nile virus (WNV) is a mosquito-borne flavivirus causing different forms of infection among humans, varying from asymptomatic illness to fetal central nervous system infection. Turkey lies within an endemic region for WNV. Transfusion of infected blood products is another well-documented major route of transmission. The aim of our study was to investigate the presence of WNV viremia among a healthy donor population from the western part of the country.   Materials and methods: A total of 438 healthy volunteer blood donors were included in the study. The presence of WNV RNA was investigated by quantitative real-time reverse-transcriptase polymerase chain reaction (qRT-PCR) and anti-WNV IgG was detected by a commercial ELISA test.   Results: Ages of volunteer donors were 18-62 years (mean: 34.7) and 34 (7.76%) were women. All samples were negative for WNV RNA by qRT-PCR. Eleven (2.51%) samples, 1 of which was borderline, were positive for anti-WNV IgG. All positive samples were from the western part of the country and 9 of them were from İzmir.   Conclusion: Although all donor samples were negative for WNV RNA by qRT-PCR, the risk of WNV transmission via blood products should not be ignored in endemic regions.

Makale detayları

Investigation of West Nile virus among healthy blood donors in the western part of Turkey

Yazarlar:

Servet ULUER BİÇEROĞLU | Ersin KARATAYLI | Arzu BAYRAM | Ajda TURHAN | Aysu DEĞİRMENCİ | Yeşim AYDINOK | Abdurrahman Mithat BOZDAYI | Şaziye Rüçhan SERTÖZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.84-88

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752865

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

West Nile virus

blood donors

quantitative real-time PCR

Sayı

Makale detayları

Investigation of West Nile virus among healthy blood donors in the western part of Turkey

Yazarlar: Servet ULUER BİÇEROĞLU | Ersin KARATAYLI | Arzu BAYRAM | Ajda TURHAN | Aysu DEĞİRMENCİ | Yeşim AYDINOK | Abdurrahman Mithat BOZDAYI | Şaziye Rüçhan SERTÖZ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.84-88

Belge Tipi: Makale

Yayın Tarihi: 3/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000752865

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

West Nile virus

blood donors

quantitative real-time PCR

Sayı

Yazarlar:

Servet ULUER BİÇEROĞLU | Ersin KARATAYLI | Arzu BAYRAM | Ajda TURHAN | Aysu DEĞİRMENCİ | Yeşim AYDINOK | Abdurrahman Mithat BOZDAYI | Şaziye Rüçhan SERTÖZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2015 Vol.45 Issue 1, pp.84-88

Belge Tipi:

Makale

Yayın Tarihi:

3/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000752865

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144