Antioxidant Potential and Phenolic Content of Taraxacum officinale Root Extract

Aslı Yılmaz; Sefa Gözcü

Makale detayları

Antioxidant Potential and Phenolic Content of Taraxacum officinale Root Extract

Yazarlar:

Aslı Yılmaz | Sefa Gözcü

Yayıncı:

Ataturk University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Pharmata Vol.5 Issue 2, pp.33-37

Belge Tipi:

Makale

Yayın Tarihi:

7/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001355462

pISSN:

2980-1966

Anahtar kelimeler:

Özet:

 Objective: The purpose of this study was to assess the antioxidant capability and bioactive chemical profile of Taraxacum officinale roots, a medicinal plant with potential therapeutic uses. Methods: 70 methanol was used to extract the roots, and the solvent was then evaporated. Both the total flavonoid content TFC and the total phenolic content TPC were measured. The DPPH, ABTS, and FRAP tests were used to measure antioxidant capability. Results: The IC50 values for DPPH and ABTS assays were 50.470.41 µgmL and 70.570.44 µgmL, respectively. The reducing power, measured by the FRAP assay, was 26.87  0.12 mg Trolox equivalentsg extract. The TPC was 23.58  0.97 mg gallic acid equivalentsg extract, and the TFC was 7.76  0.81 mg quercetin equivalentsg extract. Conclusion: Taraxacum officinale root extracts high phenolic and flavonoid content contributes to explain its modest antioxidant activity. These findings indicate its potential use as a natural antioxidant source in the pharmaceutical and nutraceutical industries.

 Objective: The purpose of this study was to assess the antioxidant capability and bioactive chemical profile of Taraxacum officinale roots, a medicinal plant with potential therapeutic uses. Methods: 70 methanol was used to extract the roots, and the solvent was then evaporated. Both the total flavonoid content TFC and the total phenolic content TPC were measured. The DPPH, ABTS, and FRAP tests were used to measure antioxidant capability. Results: The IC50 values for DPPH and ABTS assays were 50.470.41 µgmL and 70.570.44 µgmL, respectively. The reducing power, measured by the FRAP assay, was 26.87  0.12 mg Trolox equivalentsg extract. The TPC was 23.58  0.97 mg gallic acid equivalentsg extract, and the TFC was 7.76  0.81 mg quercetin equivalentsg extract. Conclusion: Taraxacum officinale root extracts high phenolic and flavonoid content contributes to explain its modest antioxidant activity. These findings indicate its potential use as a natural antioxidant source in the pharmaceutical and nutraceutical industries.

 Objective: The purpose of this study was to assess the antioxidant capability and bioactive chemical profile of Taraxacum officinale roots, a medicinal plant with potential therapeutic uses. Methods: 70 methanol was used to extract the roots, and the solvent was then evaporated. Both the total flavonoid content TFC and the total phenolic content TPC were measured. The DPPH, ABTS, and FRAP tests were used to measure antioxidant capability. Results: The IC50 values for DPPH and ABTS assays were 50.470.41 µgmL and 70.570.44 µgmL, respectively. The reducing power, measured by the FRAP assay, was 26.87  0.12 mg Trolox equivalentsg extract. The TPC was 23.58  0.97 mg gallic acid equivalentsg extract, and the TFC was 7.76  0.81 mg quercetin equivalentsg extract. Conclusion: Taraxacum officinale root extracts high phenolic and flavonoid content contributes to explain its modest antioxidant activity. These findings indicate its potential use as a natural antioxidant source in the pharmaceutical and nutraceutical industries.

 Amaç: Bu çalışmanın amacı, potansiyel terapötik kullanımla sahip, tıbbi bir bitki olan Taraxacum officinale köklerinin antioksidan kapasitesini ve biyoaktif kimyasal profilini değerlendirmektir. Yöntemler: Köklern ekstraksiyonu için 70 metanol kullanılmış ve ardından çözücü buharlaştırılmıştır. Hem toplam flavonoid içeriği TFC hem de toplam fenolik içerik TPC ölçülmüştür. Antioksidan kapasitesini ölçmek için DPPH, ABTS ve FRAP testleri kullanılmıştır. Sonuçlar: DPPH ve ABTS analizleri için IC50 değerleri sırasıyla 50,470,41 µgmL ve 70,570,44 µgmL olarak tespit edilmiştir. FRAP analizi ile ölçülen indirgeyici güç, 26,87  0,12 mg Trolox eşdeğerig özüt olarak belirlenmiştir. TPC 23,58  0,97 mg gallik asit eşdeğerig özüt ve TFC 7,76  0,81 mg kuersetin eşdeğerig özüt olarak bulunmuştur. Sonuç: Taraxacum officinale kök özütünün yüksek fenolik ve flavonoid içeriği, orta derecede antioksidan aktivitesini açıklamaktadır. Bu bulgular, farmasötik ve nutrasötik endüstrilerinde doğal bir antioksidan kaynağı olarak potansiyel kullanımını göstermektedir.

Makale detayları

Antioxidant Potential and Phenolic Content of Taraxacum officinale Root Extract

Yazarlar:

Aslı Yılmaz | Sefa Gözcü

Yayıncı:

Ataturk University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Pharmata Vol.5 Issue 2, pp.33-37

Belge Tipi:

Makale

Yayın Tarihi:

7/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001355462

pISSN:

2980-1966

ABTS

DPPH

FRAP

Taraxacum officinale (L.) Weber ex F.H. WiggABTS

DPPH

FRAP

Taraxacum officinale (L.) Weber ex F.H. Wigg

Sayı

Makale detayları

Yazarlar: Aslı Yılmaz | Sefa Gözcü

Yayıncı: Ataturk University

Ana Başlıklar: Pharmacology and Pharmaceutical Sciences (Other)

Dergi: Pharmata Vol.5 Issue 2, pp.33-37

Belge Tipi: Makale

Yayın Tarihi: 7/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001355462

pISSN: 2980-1966

Sayı

Yazarlar:

Aslı Yılmaz | Sefa Gözcü

Yayıncı:

Ataturk University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Pharmata Vol.5 Issue 2, pp.33-37

Belge Tipi:

Makale

Yayın Tarihi:

7/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001355462

pISSN:

2980-1966