The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure

Seçkin DERELİ

doi:https://doi.org/10.5798/dicletip.850294

Makale detayları

The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure

Yazarlar:

Seçkin DERELİ

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Dicle Medical Journal 2020 Vol.47 Issue 4, pp.812-819

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000946348

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945

DOI:

https://doi.org/10.5798/dicletip.850294

Özet:

 

Objective: We purposed to evaluate the association between Monocyte To High-Density Lipoprotein Cholesterol Ratio (MHR) and mortality during a year follow-up in patients with reduced efection fraction heart failure (HFrEF).
Method: We included total of 552 patients with HFrEF into the study. The main outcome was mortality at 1-year follow-up. Sociodemographic characteristics, hemogram and biochemical parameters, ejection fractions of patients were recorded. MHR was was computed by splitting monocyte into high-density lipoprotein cholesterol (HDL-C).
Results: The HFrEF population were seperated into different groups as non-survivors (n=45) and survivors (n=507). When the groups are compared the non-survivors group was older (p=0.04) and chronic renal failure incidence was higher in non-survivors (p=0.001). The MHR was notably higher in the non-survivors group (p=0.000). We have shown that MHR had a positive correlation with mortality (r=0.146 p=0.001). Also higher MHR was found as a strong paramer to predict of mortality (Odds ratio: 2.471, 95% confidence interval: 1.729–4.092, P=0.005). The cut-off values of 6,39 might be applied for predicting the mortality with 88% sensitivity and 97% specificity [Area under curve:0.831 (95% Confidence Interval: 0.799-0.869) p=0.001].
Conclusion: MHR can be used as an easy and usefull tool to predict mortality in HFrEF patients.

Makale detayları

The Monocyte To High-Density Lipoprotein Cholesterol Ratio Predicts The Mortality in Patients With Reduced Ejection Fraction Heart Failure

Yazarlar: Seçkin DERELİ

Yayıncı: Dicle University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Dicle Medical Journal 2020 Vol.47 Issue 4, pp.812-819

Belge Tipi: Makale

Yayın Tarihi: 12/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000946348

Sıklık: Üç Aylık

eISSN: 1308-9889

pISSN: 1300-2945

DOI: https://doi.org/10.5798/dicletip.850294

Sayı

Yazarlar:

Seçkin DERELİ

Yayıncı:

Dicle University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Dicle Medical Journal 2020 Vol.47 Issue 4, pp.812-819

Belge Tipi:

Makale

Yayın Tarihi:

12/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000946348

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945

DOI:

https://doi.org/10.5798/dicletip.850294