Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

Şafak AKIN; Duygu Yazgan AKSOY; Serkan AKIN; Mehmet KILIÇ; Fahri YETİŞİR; Miyase BAYRAKTAR

Makale detayları

Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

Yazarlar:

Şafak AKIN | Duygu Yazgan AKSOY | Serkan AKIN | Mehmet KILIÇ | Fahri YETİŞİR | Miyase BAYRAKTAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1723-1727

Belge Tipi:

Makale

Yayın Tarihi:

11/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000750976

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: The purpose of this study was to analyze the clinicopathological characteristics of patients with papillary thyroid carcinoma (PTC) and papillary thyroid microcarcinoma (PTMC) and predictive factors for central lymph node metastasis (CLNM).Materials and methods: Patients diagnosed as having PTC and PTMC were evaluated. Clinical and laboratory parameters were recorded.Results: The mean age at diagnosis was 47.3 +- 11.9 years. Of all 223 patients, 91 (40.8%) had lymph nodes removed, 29 of whom had lymph node metastasis and 24 of whom had only CLNM. Univariate analysis revealed that central lymph node metastasis was associated with male sex, presence of bilaterality, presence of extrathyroidal extension, and tumor size (P = 0.033, P = 0.027, P < 0.001, P < 0.001, respectively). However, multivariate logistic regression analysis showed that sex, age, tumor size, multifocality, bilaterality, extrathyroidal extension, clinical suspicion, and chronic lymphocytic thyroiditis were not significantly correlated with an increased risk for CLNM.Conclusion: Lymph node metastasis is known to be a significant predictor of locoregional recurrence in patients with PTC and PTMC. Further prospective studies are needed to identify the extent of surgery such as central lymph node dissection in patients with PTC or PTMC.

Makale detayları

Prediction of central lymph node metastasis in patientswith thyroid papillary microcarcinoma

Yazarlar: Şafak AKIN | Duygu Yazgan AKSOY | Serkan AKIN | Mehmet KILIÇ | Fahri YETİŞİR | Miyase BAYRAKTAR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1723-1727

Belge Tipi: Makale

Yayın Tarihi: 11/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000750976

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Şafak AKIN | Duygu Yazgan AKSOY | Serkan AKIN | Mehmet KILIÇ | Fahri YETİŞİR | Miyase BAYRAKTAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1723-1727

Belge Tipi:

Makale

Yayın Tarihi:

11/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000750976

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144