Bloodstream infections in pediatric hematology/oncology patients: Six years? experience of a single center in Turkey

Tuğçe Tural KARA; Tuğba ERAT; Aysun YAHŞİ; Halil ÖZDEMİR; Dilber Talia İLERİ; Elif İNCE; Nurdan TAÇYILDIZ; Emel ÜNAL; Ergin ÇİFTCİ; Erdal İNCE

Makale detayları

Bloodstream infections in pediatric hematology/oncology patients: Six years? experience of a single center in Turkey

Yazarlar:

Tuğçe Tural KARA | Tuğba ERAT | Aysun YAHŞİ | Halil ÖZDEMİR | Dilber Talia İLERİ | Elif İNCE | Nurdan TAÇYILDIZ | Emel ÜNAL | Ergin ÇİFTCİ | Erdal İNCE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.1157-1164

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750018

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim:  Bloodstream  infections  are  the  major  cause  of  morbidity,  increased  cost,  prolonged  hospitalization,  and  mortality  in pediatric patients. Identifying the predominant microorganisms and antimicrobial susceptibilities in centers helps to select effective empirical  antimicrobials  which  leads  to  positive  clinical  outcomes.  We  aimed  to  identify  the  causative  microorganisms  and  their  antimicrobial susceptibilities in patients with bloodstream infections.Materials and methods: Data belonging to patients with hematological and/or oncological diseases admitted to our hospital with fever between January 2010 and November 2015 were analyzed. Results: In total, 71 patients who had 111 bloodstream infection episodes were included. Responsible pathogens were detected as follows: 35.1%  gram-positive  microorganisms,  60.5%  gram-negative  bacteria,  and  4.4%  fungi.  The  most  common  causative  gram-negative  pathogen was Escherichia coli and the most commonly isolated gram-positive microorganism was coagulase-negative staphylococci.Conclusion: Gram-negative microorganisms were predominant pathogens in bloodstream infections. Escherichia coli and coagulase-negative  staphylococci  were  the  most  commonly  isolated  responsible  pathogens.  Beta-lactam/lactamase  inhibitors  were  suitable  for  empirical  treatment.  However,  in  critical  cases,  colistin  could  have  been  used  for  empirical  treatment  until  the  culture  results  were  available. Routine glycopeptide use was not required. By identifying the causative microorganisms and their antimicrobial resistance patterns, it will be possible to obtain positive clinical results.

Makale detayları

Bloodstream infections in pediatric hematology/oncology patients: Six years? experience of a single center in Turkey

Yazarlar: Tuğçe Tural KARA | Tuğba ERAT | Aysun YAHŞİ | Halil ÖZDEMİR | Dilber Talia İLERİ | Elif İNCE | Nurdan TAÇYILDIZ | Emel ÜNAL | Ergin ÇİFTCİ | Erdal İNCE

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.1157-1164

Belge Tipi: Makale

Yayın Tarihi: 7/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000750018

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Tuğçe Tural KARA | Tuğba ERAT | Aysun YAHŞİ | Halil ÖZDEMİR | Dilber Talia İLERİ | Elif İNCE | Nurdan TAÇYILDIZ | Emel ÜNAL | Ergin ÇİFTCİ | Erdal İNCE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.1157-1164

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750018

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144