Synthesis of 5-aryl-N -(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide via three-component reaction of trichloroacetyl isocyanate, (N -isocyanimino)triphenylphosphorane, and benzoic acid derivatives

NAHID SHAJARI; ALI REZA KAZEMIZADEH; ALI RAMAZANI

doi:https://doi.org/10.3906/kim-1501-43

Makale detayları

Synthesis of 5-aryl-N -(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide via three-component reaction of trichloroacetyl isocyanate, (N -isocyanimino)triphenylphosphorane, and benzoic acid derivatives

Yazarlar:

NAHID SHAJARI | ALI REZA KAZEMIZADEH | ALI RAMAZANI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2015 Vol.39 Issue 4, pp.874-879

Belge Tipi:

Makale

Yayın Tarihi:

8/2015

Belge Dili:

İngilizce

Document ID (Org No.):

2000726837

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1501-43

Özet:

 

The three-component reaction of benzoic acid derivatives, (NNN-isocyanimino)triphenylphosphorane, and trichloroacetyl isocyanate in a 1:1:1 ratio in CH33_{3}CN occurred at room temperature, and the 5-aryl-NNN-(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide derivatives produced were formed in high yields. The reaction proceeded smoothly and cleanly under mild reaction conditions and no side reactions were observed. The structures of the products were confirmed by IR, 11^{1}H NMR, 1313^{13}C NMR, mass spectroscopy, and elemental analysis.

 

The three-component reaction of benzoic acid derivatives, (NNN-isocyanimino)triphenylphosphorane, and trichloroacetyl isocyanate in a 1:1:1 ratio in CH33_{3}CN occurred at room temperature, and the 5-aryl-NNN-(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide derivatives produced were formed in high yields. The reaction proceeded smoothly and cleanly under mild reaction conditions and no side reactions were observed. The structures of the products were confirmed by IR, 11^{1}H NMR, 1313^{13}C NMR, mass spectroscopy, and elemental analysis.

Makale detayları

Synthesis of 5-aryl-N -(trichloroacetyl)-1,3,4-oxadiazole-2-carboxamide via three-component reaction of trichloroacetyl isocyanate, (N -isocyanimino)triphenylphosphorane, and benzoic acid derivatives

Yazarlar: NAHID SHAJARI | ALI REZA KAZEMIZADEH | ALI RAMAZANI

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2015 Vol.39 Issue 4, pp.874-879

Belge Tipi: Makale

Yayın Tarihi: 8/2015

Belge Dili: İngilizce

Document ID (Org No.): 2000726837

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/kim-1501-43

Sayı

Yazarlar:

NAHID SHAJARI | ALI REZA KAZEMIZADEH | ALI RAMAZANI

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2015 Vol.39 Issue 4, pp.874-879

Belge Tipi:

Makale

Yayın Tarihi:

8/2015

Belge Dili:

İngilizce

Document ID (Org No.):

2000726837

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1501-43