Inhibitory activity of Lactobacillus plantarum ATCC 8014  fermented milk combined with aqueous extract of Moringa  oleifera leaves against Streptococcus mutans

N.A.

Makale detayları

Inhibitory activity of Lactobacillus plantarum ATCC 8014 fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutans

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.23 Issue 4, pp.701-710

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347689

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 The growth inhibitory activity of Lactobacillus plantarum ATCC 8014 Lp fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutants has been studied. The preparation is potential developed as healthy food due to its nutritional value as well as its beneficial activities. The well agar diffusion method was applied for the antibacterial assay on nutrient agar media and local strain of Streptococcus mutants was used as a bacterial test. This species often causes infectious in the teeth. Effectiveness of the fermented milk and its combination with aqueous extract preparations against the bacterial test were assessed by minimum inhibitory concentration MIC for the potency indication. The aqueous extract of Moringa oleifera leaves was prepared as infuse like according to community daily consumption. Concentration of the extract used in the formulation was higher than the MIC. The result showed that the MIC of the aqueous extract of Moringa oleifera leaves and the L. plantarum fermented milk were 20 and 35 with growth inhibition zone diameter of 11.70  0.28 mm and 12.02  0.83 mm, respectively. The combination of fermented milk and aqueous extract was prepared in various ratio concentration 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1. The optimum ratio of the combination was 2:8 with growth inhibition zone diameter of 16.53  0.32 mm and the MIC value at optimum ratio was 45 with inhibition zone diameter of 11.90  0.86 mm.

 The growth inhibitory activity of Lactobacillus plantarum ATCC 8014 Lp fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutants has been studied. The preparation is potential developed as healthy food due to its nutritional value as well as its beneficial activities. The well agar diffusion method was applied for the antibacterial assay on nutrient agar media and local strain of Streptococcus mutants was used as a bacterial test. This species often causes infectious in the teeth. Effectiveness of the fermented milk and its combination with aqueous extract preparations against the bacterial test were assessed by minimum inhibitory concentration MIC for the potency indication. The aqueous extract of Moringa oleifera leaves was prepared as infuse like according to community daily consumption. Concentration of the extract used in the formulation was higher than the MIC. The result showed that the MIC of the aqueous extract of Moringa oleifera leaves and the L. plantarum fermented milk were 20 and 35 with growth inhibition zone diameter of 11.70  0.28 mm and 12.02  0.83 mm, respectively. The combination of fermented milk and aqueous extract was prepared in various ratio concentration 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1. The optimum ratio of the combination was 2:8 with growth inhibition zone diameter of 16.53  0.32 mm and the MIC value at optimum ratio was 45 with inhibition zone diameter of 11.90  0.86 mm.

 The growth inhibitory activity of Lactobacillus plantarum ATCC 8014 Lp fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutants has been studied. The preparation is potential developed as healthy food due to its nutritional value as well as its beneficial activities. The well agar diffusion method was applied for the antibacterial assay on nutrient agar media and local strain of Streptococcus mutants was used as a bacterial test. This species often causes infectious in the teeth. Effectiveness of the fermented milk and its combination with aqueous extract preparations against the bacterial test were assessed by minimum inhibitory concentration MIC for the potency indication. The aqueous extract of Moringa oleifera leaves was prepared as infuse like according to community daily consumption. Concentration of the extract used in the formulation was higher than the MIC. The result showed that the MIC of the aqueous extract of Moringa oleifera leaves and the L. plantarum fermented milk were 20 and 35 with growth inhibition zone diameter of 11.70  0.28 mm and 12.02  0.83 mm, respectively. The combination of fermented milk and aqueous extract was prepared in various ratio concentration 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1. The optimum ratio of the combination was 2:8 with growth inhibition zone diameter of 16.53  0.32 mm and the MIC value at optimum ratio was 45 with inhibition zone diameter of 11.90  0.86 mm.

 The growth inhibitory activity of Lactobacillus plantarum ATCC 8014 Lp fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutants has been studied. The preparation is potential developed as healthy food due to its nutritional value as well as its beneficial activities. The well agar diffusion method was applied for the antibacterial assay on nutrient agar media and local strain of Streptococcus mutants was used as a bacterial test. This species often causes infectious in the teeth. Effectiveness of the fermented milk and its combination with aqueous extract preparations against the bacterial test were assessed by minimum inhibitory concentration MIC for the potency indication. The aqueous extract of Moringa oleifera leaves was prepared as infuse like according to community daily consumption. Concentration of the extract used in the formulation was higher than the MIC. The result showed that the MIC of the aqueous extract of Moringa oleifera leaves and the L. plantarum fermented milk were 20 and 35 with growth inhibition zone diameter of 11.70  0.28 mm and 12.02  0.83 mm, respectively. The combination of fermented milk and aqueous extract was prepared in various ratio concentration 1:9, 2:8, 3:7, 4:6, 5:5, 6:4, 7:3, 8:2, and 9:1. The optimum ratio of the combination was 2:8 with growth inhibition zone diameter of 16.53  0.32 mm and the MIC value at optimum ratio was 45 with inhibition zone diameter of 11.90  0.86 mm.

Makale detayları

Inhibitory activity of Lactobacillus plantarum ATCC 8014 fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutans

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.23 Issue 4, pp.701-710

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347689

pISSN:

2630-6344

Growth inhibitory

aqueous extract

Moringa oleifera

fermented milk

Lactobacillus plantarum.

Sayı

Makale detayları

Inhibitory activity of Lactobacillus plantarum ATCC 8014 fermented milk combined with aqueous extract of Moringa oleifera leaves against Streptococcus mutans

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacognosy | Pharmaceutical Chemistry

Dergi: Journal of Research in Pharmacy Vol.23 Issue 4, pp.701-710

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001347689

pISSN: 2630-6344

Growth inhibitory

aqueous extract

Moringa oleifera

fermented milk

Lactobacillus plantarum.

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacognosy | Pharmaceutical Chemistry

Dergi:

Journal of Research in Pharmacy Vol.23 Issue 4, pp.701-710

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001347689

pISSN:

2630-6344