DISSEMINE INTRAVASCULAR COAGULATION MAY BE THE PRESENTING FEATURE FOR CHRONIC MYELOMONOCYTIC LEUKEMIA

Itır ŞİRİNOĞLU DEMİRİZ; A. Gülsan TÜRKÖZ SUCAK

Makale detayları

DISSEMINE INTRAVASCULAR COAGULATION MAY BE THE PRESENTING FEATURE FOR CHRONIC MYELOMONOCYTIC LEUKEMIA

Yazarlar:

Itır ŞİRİNOĞLU DEMİRİZ | A. Gülsan TÜRKÖZ SUCAK

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Istanbul Faculty of Medicine 2020 Vol.83 Issue 4, pp.307-308

Belge Tipi:

Makale

Yayın Tarihi:

10/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000515753

Sıklık:

Üç Aylık

eISSN:

1305-6441

Özet:

 

Chronic myelomonocytic leukemia (CMML) is a malignant myeloid stem cell disease accompanied by dysplasia in the context of myeloproliferative disease. Peripheral cytopenias (mainly anemia and thrombocytopenia) and hepatosplenomegaly are common findings. Dramatic leukocytosis can also be seen without transformation to acute myeloid leukemia (AML). In some cases, this is associated with leukostasis and end organ damage. Splenomegaly is present in up to 25% of patients and is often accompanied by hepatomegaly, lymphadenopathy, or nodular cutaneous leukemic infiltrates. The acquired cogulation defect may be due to factor X binding to atypical monocytes, resulting in acquired factor X deficiency. We would like to highlight the challenging diagnosis and treatment of CMML.

Makale detayları

DISSEMINE INTRAVASCULAR COAGULATION MAY BE THE PRESENTING FEATURE FOR CHRONIC MYELOMONOCYTIC LEUKEMIA

Yazarlar: Itır ŞİRİNOĞLU DEMİRİZ | A. Gülsan TÜRKÖZ SUCAK

Yayıncı: Istanbul University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Istanbul Faculty of Medicine 2020 Vol.83 Issue 4, pp.307-308

Belge Tipi: Makale

Yayın Tarihi: 10/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000515753

Sıklık: Üç Aylık

eISSN: 1305-6441

Sayı

Yazarlar:

Itır ŞİRİNOĞLU DEMİRİZ | A. Gülsan TÜRKÖZ SUCAK

Yayıncı:

Istanbul University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Istanbul Faculty of Medicine 2020 Vol.83 Issue 4, pp.307-308

Belge Tipi:

Makale

Yayın Tarihi:

10/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000515753

Sıklık:

Üç Aylık

eISSN:

1305-6441