Investigation of COVID-19 Vaccination and Disease Status in Behçet’s Patients

N.A.

Makale detayları

Investigation of COVID-19 Vaccination and Disease Status in Behçet’s Patients

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.206-212

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001349848

pISSN:

0365-8104

Anahtar kelimeler:

Özet:

 Objectives: Behçets disease is a vasculitis of unknown cause that can affect many systems, especially the skin, mucosa, joint and eyes. In this study, coronavirus disease-2019 COVID-19 and vaccination status in Behçets patients were examined. The relationship between the characteristics of Behçets patients and the data related to COVID-19 was investigated. Materials and Methods: Three hundred and three Behçets patients were randomly included in this study. The vaccination status of the patients and the type of COVID-19 vaccine administered were questioned. Whether the patients had COVID-19 and the disease process were examined. Behçets patients with a positive COVID-19 polymerase chain reaction PCR test were considered to have had the disease. Results: The mean age was 46.3 12.3 years, 40.6 were male, and the age at diagnosis was 30.4 9.1 years. COVID-19 PCR test positivity was detected in 132 43.5 of the patients. It was observed that 72 n95 of the patients with test positivity were symptomatic and the hospitalization rate was 3. It was observed that Behçets patients who had COVID-19 had less central nervous system involvement than those who did not p0.01. No significant correlation was found between other clinical manifestations of Behçets disease, age, gender, and the age at diagnosis of the disease, and the history of having COVID-19. The rate of COVID-19 vaccination in Behçets patients was 92.1 for the first dose, 89.4 for the second dose, and 60 for the third dose. It was observed that the Biontech vaccine was administered more frequently than other types of vaccines. It was detected that the number of COVID-19 vaccinations was significantly higher in the group that did not have COVID-19 p0.003. Conclusion: In this study, although the rate of COVID-19 disease was high in Behçets patients, the rate of hospitalization was low. The importance of COVID-19 vaccination was emphasized. Key Words: Behçets Disease, Vasculitis, COVID-19, Vaccination.

 Objectives: Behçets disease is a vasculitis of unknown cause that can affect many systems, especially the skin, mucosa, joint and eyes. In this study, coronavirus disease-2019 COVID-19 and vaccination status in Behçets patients were examined. The relationship between the characteristics of Behçets patients and the data related to COVID-19 was investigated. Materials and Methods: Three hundred and three Behçets patients were randomly included in this study. The vaccination status of the patients and the type of COVID-19 vaccine administered were questioned. Whether the patients had COVID-19 and the disease process were examined. Behçets patients with a positive COVID-19 polymerase chain reaction PCR test were considered to have had the disease. Results: The mean age was 46.3 12.3 years, 40.6 were male, and the age at diagnosis was 30.4 9.1 years. COVID-19 PCR test positivity was detected in 132 43.5 of the patients. It was observed that 72 n95 of the patients with test positivity were symptomatic and the hospitalization rate was 3. It was observed that Behçets patients who had COVID-19 had less central nervous system involvement than those who did not p0.01. No significant correlation was found between other clinical manifestations of Behçets disease, age, gender, and the age at diagnosis of the disease, and the history of having COVID-19. The rate of COVID-19 vaccination in Behçets patients was 92.1 for the first dose, 89.4 for the second dose, and 60 for the third dose. It was observed that the Biontech vaccine was administered more frequently than other types of vaccines. It was detected that the number of COVID-19 vaccinations was significantly higher in the group that did not have COVID-19 p0.003. Conclusion: In this study, although the rate of COVID-19 disease was high in Behçets patients, the rate of hospitalization was low. The importance of COVID-19 vaccination was emphasized. Key Words: Behçets Disease, Vasculitis, COVID-19, Vaccination.

 Objectives: Behçets disease is a vasculitis of unknown cause that can affect many systems, especially the skin, mucosa, joint and eyes. In this study, coronavirus disease-2019 COVID-19 and vaccination status in Behçets patients were examined. The relationship between the characteristics of Behçets patients and the data related to COVID-19 was investigated. Materials and Methods: Three hundred and three Behçets patients were randomly included in this study. The vaccination status of the patients and the type of COVID-19 vaccine administered were questioned. Whether the patients had COVID-19 and the disease process were examined. Behçets patients with a positive COVID-19 polymerase chain reaction PCR test were considered to have had the disease. Results: The mean age was 46.3 12.3 years, 40.6 were male, and the age at diagnosis was 30.4 9.1 years. COVID-19 PCR test positivity was detected in 132 43.5 of the patients. It was observed that 72 n95 of the patients with test positivity were symptomatic and the hospitalization rate was 3. It was observed that Behçets patients who had COVID-19 had less central nervous system involvement than those who did not p0.01. No significant correlation was found between other clinical manifestations of Behçets disease, age, gender, and the age at diagnosis of the disease, and the history of having COVID-19. The rate of COVID-19 vaccination in Behçets patients was 92.1 for the first dose, 89.4 for the second dose, and 60 for the third dose. It was observed that the Biontech vaccine was administered more frequently than other types of vaccines. It was detected that the number of COVID-19 vaccinations was significantly higher in the group that did not have COVID-19 p0.003. Conclusion: In this study, although the rate of COVID-19 disease was high in Behçets patients, the rate of hospitalization was low. The importance of COVID-19 vaccination was emphasized. Key Words: Behçets Disease, Vasculitis, COVID-19, Vaccination.

 Amaç: Behçet hastalığı deri, mukoza, eklem ve göz başta olmak üzere birçok sistemi tutabilen, nedeni bilinmeyen bir vaskülittir. Bu çalışmada Behçet hastalarında koronavirüs hastalığı-2019 COVID-19 ve aşılama durumu incelendi. Behçet hastalarına ait özelliklerin, COVID-19 ile ilgili verilerle olan ilişkisi sorgulandı. Gereç ve Yöntem: Bu çalışmaya 303 Behçet hastası rastgele bir şekilde dahil edildi. Hastaların aşılanma durumu ve yapılan COVID-19 aşısının türü sorgulandı. COVID-19 geçirip geçirmediği ve hastalığın nasıl seyrettiği incelendi. COVID-19 polimeraz zincir reaksiyonu PCR testi pozitif olan Behçet hastaları, hastalığı geçirmiş olarak kabul edildi. Bulgular: Behçet hastalarının 40,6sı erkek, yaş ortalaması 46,3 12,3, hastalık tanı yaşı 30,4 9,1 yıl olarak saptandı. Hastaların 132sinde 43,5 COVID-19 PCR testi pozitifliği tespit edildi. Test pozitifliği olan hastaların 72sinin n95 semptomatik seyrettiği ve hastaneye yatış oranının 3 olduğu görüldü. COVID-19 geçiren Behçet hastalarında, geçirmeyenlere göre daha az oranda santral sinir sistemi tutulumu olduğu görüldü p0,01 Behçet hastalığının diğer klinik tutulumları, yaş, cinsiyet ve hastalık tanı yaşı ile COVID-19 geçirme öyküsü arasında anlamlı ilişki saptanmadı. Behçet hastalarında COVID-19 aşılamasında 1. doz aşı oranı 92,1, 2. doz için 89,4, 3. doz için 60 saptandı. Biontech aşısının diğer aşı türlerine göre daha sık oranda yapıldığı görüldü. COVID-19 aşılama sayısının, COVID-19 geçirmeyen grupta anlamlı olarak daha fazla olduğu tespit edildi p0,003. Sonuç: Bu çalışmada Behçet hastalarında COVID-19 hastalığı oranı yüksek olsa da hastaneye yatış oranı düşük görüldü. COVID-19 aşılamasının önemi vurgulandı. Anahtar Kelimeler: Behçet Hastalığı, Vaskülit, COVID-19, Aşılama.

Makale detayları

Investigation of COVID-19 Vaccination and Disease Status in Behçet’s Patients

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.206-212

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001349848

pISSN:

0365-8104

Behçet’s Disease

Vasculitis

COVID-19

VaccinationBehçet Hastalığı

Vaskülit

COVID-19

Aşılama

Sayı

Makale detayları

Yazarlar: N.A.

Yayıncı: Ankara University

Ana Başlıklar: Rheumatology and Arthritis

Dergi: Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.206-212

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001349848

pISSN: 0365-8104

Sayı

Yazarlar:

N.A.

Yayıncı:

Ankara University

Ana Başlıklar:

Rheumatology and Arthritis

Dergi:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.206-212

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001349848

pISSN:

0365-8104