IS THE HYALURONIC ACID BENEFICAL FOR THE BONE HEALING IN DEFECTS OF CRITICAL SIZE IN ANGULUS MANDIBLE AREA?: AN EXPERIMENTAL STUDY

Aykut KAHVECİ; Mustafa ÖZTÜRK; Sibel Elif GÜLTEKİN

Makale detayları

IS THE HYALURONIC ACID BENEFICAL FOR THE BONE HEALING IN DEFECTS OF CRITICAL SIZE IN ANGULUS MANDIBLE AREA?: AN EXPERIMENTAL STUDY

Yazarlar:

Aykut KAHVECİ | Mustafa ÖZTÜRK | Sibel Elif GÜLTEKİN

Yayıncı:

Istanbul Aydin University

Dergi:

Aydın Dental Journal 2018 Vol.4 Issue 2, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

10/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000920618

Sıklık:

İki Yıllık

eISSN:

2717-6835

pISSN:

2149-5572

Anahtar kelimeler:

Özet:

 


This study was aimed to evaluate the effect of hyaluronic acid on bone healing in an angulus mandible defect of a rabbit. Twenty-four New Zealand white male rabbits were used in this study. Bilateral 9x5 mm defects were made on the left and right angulus mandible of each rabbit. The left defect was filled with hyaluronic acid gel (experimental one), while the right defect was left for normal healing (control one). The rabbits were randomly divided and sacrificed during the 1st ,2nd ,3rd and 4th weeks postoperatively. The defect sites were evaluated by histologic analyses for bone healing at all healing interval. According to the histopathological examination results, there was statistically significant difference in the amount of new bone formation between hyaluronic acid and control groups (P < 0.05). On the 21st and 28th days, the amount of new bone formation was higher in hyaluronic acid groups. The inflammation scores were statistically lower in the hyaluronic acid group than the control group on the 28th day. Local injections of hyaluronic acid in mandibular critical size bone defect may improve new bone formation. Hyaluronic acid could be taken as a graft material for bone defects.

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Makale detayları

IS THE HYALURONIC ACID BENEFICAL FOR THE BONE HEALING IN DEFECTS OF CRITICAL SIZE IN ANGULUS MANDIBLE AREA?: AN EXPERIMENTAL STUDY

Yazarlar:

Aykut KAHVECİ | Mustafa ÖZTÜRK | Sibel Elif GÜLTEKİN

Yayıncı:

Istanbul Aydin University

Dergi:

Aydın Dental Journal 2018 Vol.4 Issue 2, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

10/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000920618

Sıklık:

İki Yıllık

eISSN:

2717-6835

pISSN:

2149-5572

Bone healing

hyaluronic acid

rabbits

Sayı

Makale detayları

IS THE HYALURONIC ACID BENEFICAL FOR THE BONE HEALING IN DEFECTS OF CRITICAL SIZE IN ANGULUS MANDIBLE AREA?: AN EXPERIMENTAL STUDY

Yazarlar: Aykut KAHVECİ | Mustafa ÖZTÜRK | Sibel Elif GÜLTEKİN

Yayıncı: Istanbul Aydin University

Dergi: Aydın Dental Journal 2018 Vol.4 Issue 2, pp.1-8

Belge Tipi: Makale

Yayın Tarihi: 10/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000920618

Sıklık: İki Yıllık

eISSN: 2717-6835

pISSN: 2149-5572

Bone healing

hyaluronic acid

rabbits

Sayı

Yazarlar:

Aykut KAHVECİ | Mustafa ÖZTÜRK | Sibel Elif GÜLTEKİN

Yayıncı:

Istanbul Aydin University

Dergi:

Aydın Dental Journal 2018 Vol.4 Issue 2, pp.1-8

Belge Tipi:

Makale

Yayın Tarihi:

10/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000920618

Sıklık:

İki Yıllık

eISSN:

2717-6835

pISSN:

2149-5572