The formulation of ginger oil nanoemulsions of three varieties of ginger (Zingiber officinale Rosc.) as natural antioxidant

N.A.

Makale detayları

The formulation of ginger oil nanoemulsions of three varieties of ginger (Zingiber officinale Rosc.) as natural antioxidant

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.24 Issue 6, pp.914-924

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001348016

pISSN:

2630-6344

Anahtar kelimeler:

Özet:

 One of traditional plants in Indonesia that could be potentially developed as antioxidant is ginger Zingiber officinale Rosc.. There are three varieties, namely elephant ginger, yellow ginger, and red ginger. Its contents mainly essential oil consisted of many antioxidant compounds. Nevertheless, the use of ginger oil in topical dosage form formula is less effective, unstable, and volatile which affects its bioavailability. In this study, nanoemulsion formulas of ginger oil were optimized according to the ratio of tween 80 as surfactant and ethanol as cosurfactant using simplex lattice design SLD method. The optimum nanoemulsion formulas of each varieties were characterized and the result showed that nanoemulsion of yellow ginger oil had the highest percentage transmittance 99.676  0.096 and halfmaximal inhibitory concentration IC50 value 3.010  0.008 mgmL. Furthermore, all optimum formulas had complied the other nanoemulsion specifications. The study indicated that nanoemulsion formulas of three varieties of ginger essential oils could be developed as potential antioxidant agent.

 One of traditional plants in Indonesia that could be potentially developed as antioxidant is ginger Zingiber officinale Rosc.. There are three varieties, namely elephant ginger, yellow ginger, and red ginger. Its contents mainly essential oil consisted of many antioxidant compounds. Nevertheless, the use of ginger oil in topical dosage form formula is less effective, unstable, and volatile which affects its bioavailability. In this study, nanoemulsion formulas of ginger oil were optimized according to the ratio of tween 80 as surfactant and ethanol as cosurfactant using simplex lattice design SLD method. The optimum nanoemulsion formulas of each varieties were characterized and the result showed that nanoemulsion of yellow ginger oil had the highest percentage transmittance 99.676  0.096 and halfmaximal inhibitory concentration IC50 value 3.010  0.008 mgmL. Furthermore, all optimum formulas had complied the other nanoemulsion specifications. The study indicated that nanoemulsion formulas of three varieties of ginger essential oils could be developed as potential antioxidant agent.

 One of traditional plants in Indonesia that could be potentially developed as antioxidant is ginger Zingiber officinale Rosc.. There are three varieties, namely elephant ginger, yellow ginger, and red ginger. Its contents mainly essential oil consisted of many antioxidant compounds. Nevertheless, the use of ginger oil in topical dosage form formula is less effective, unstable, and volatile which affects its bioavailability. In this study, nanoemulsion formulas of ginger oil were optimized according to the ratio of tween 80 as surfactant and ethanol as cosurfactant using simplex lattice design SLD method. The optimum nanoemulsion formulas of each varieties were characterized and the result showed that nanoemulsion of yellow ginger oil had the highest percentage transmittance 99.676  0.096 and halfmaximal inhibitory concentration IC50 value 3.010  0.008 mgmL. Furthermore, all optimum formulas had complied the other nanoemulsion specifications. The study indicated that nanoemulsion formulas of three varieties of ginger essential oils could be developed as potential antioxidant agent.

 One of traditional plants in Indonesia that could be potentially developed as antioxidant is ginger Zingiber officinale Rosc.. There are three varieties, namely elephant ginger, yellow ginger, and red ginger. Its contents mainly essential oil consisted of many antioxidant compounds. Nevertheless, the use of ginger oil in topical dosage form formula is less effective, unstable, and volatile which affects its bioavailability. In this study, nanoemulsion formulas of ginger oil were optimized according to the ratio of tween 80 as surfactant and ethanol as cosurfactant using simplex lattice design SLD method. The optimum nanoemulsion formulas of each varieties were characterized and the result showed that nanoemulsion of yellow ginger oil had the highest percentage transmittance 99.676  0.096 and halfmaximal inhibitory concentration IC50 value 3.010  0.008 mgmL. Furthermore, all optimum formulas had complied the other nanoemulsion specifications. The study indicated that nanoemulsion formulas of three varieties of ginger essential oils could be developed as potential antioxidant agent.

Makale detayları

The formulation of ginger oil nanoemulsions of three varieties of ginger (Zingiber officinale Rosc.) as natural antioxidant

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.24 Issue 6, pp.914-924

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001348016

pISSN:

2630-6344

Ginger oil

nanoemulsion

tween 80

ethanol

antioxidant

Sayı

Makale detayları

The formulation of ginger oil nanoemulsions of three varieties of ginger (Zingiber officinale Rosc.) as natural antioxidant

Yazarlar: N.A.

Yayıncı: Marmara University

Ana Başlıklar: Pharmacology and Pharmaceutical Sciences (Other)

Dergi: Journal of Research in Pharmacy Vol.24 Issue 6, pp.914-924

Belge Tipi: Makale

Yayın Tarihi: 6/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001348016

pISSN: 2630-6344

Ginger oil

nanoemulsion

tween 80

ethanol

antioxidant

Sayı

Yazarlar:

N.A.

Yayıncı:

Marmara University

Ana Başlıklar:

Pharmacology and Pharmaceutical Sciences (Other)

Dergi:

Journal of Research in Pharmacy Vol.24 Issue 6, pp.914-924

Belge Tipi:

Makale

Yayın Tarihi:

6/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001348016

pISSN:

2630-6344