The Relationship Between Depressive Symptoms and Treatment Adherence in Patients With Hypoparathyroidism

Zeynep Ece Demirbaş

Makale detayları

The Relationship Between Depressive Symptoms and Treatment Adherence in Patients With Hypoparathyroidism

Yazarlar:

Zeynep Ece Demirbaş

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Endocrinology | Internal Diseases

Dergi:

Developments and Experiments in Health and Medicine Vol.39 Issue 1, pp.47-60

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001342378

pISSN:

3062-2948

Anahtar kelimeler:

Özet:

 Aims: Hypoparathyroidism HPT is a chronic disease characterized by low calcium levels and significant psychological and physical complications. The aim of this study was to investigate the relationship between depressive symptoms and treatment adherence in patients with HPT. Materials and Methods: This cross-sectional, observational study included patients with chronic HPT from the endocrinology clinic of a tertiary care hospital. Adults receiving oral calcium and active vitamin D therapy, who volunteered to complete the Beck Depression Inventory BDI, and who did not have any mental disability or concomitant chronic serious disease were included. Biochemical and complication data were collected, and treatment adherence was assessed on the basis of self-reported medication use. Results: Of the 33 patients mean age 53.7  12.7 years; 78.8 female, 54.5 were non-adherent to treatment. Depressive symptoms ranged from minimal to severe, with 24.3 experiencing moderate to severe symptoms. A significant association was found between HPT etiology and depressive symptom severity p  0.011, with moderate symptoms more common in post-operative patients 34.8 vs. 0 in non-surgical cases. A weak negative correlation was observed between depressive symptom scores and highest calcium levels r  -0.359, p  0.04. Conclusions: This study emphasizes the importance of treatment goals by demonstrating the negative correlation between Ca levels and BDI scores. The high prevalence of depressive symptoms and non-adherence in patients with HPT underlines the need for tailored mental health and adherence interventions.

 Aims: Hypoparathyroidism HPT is a chronic disease characterized by low calcium levels and significant psychological and physical complications. The aim of this study was to investigate the relationship between depressive symptoms and treatment adherence in patients with HPT. Materials and Methods: This cross-sectional, observational study included patients with chronic HPT from the endocrinology clinic of a tertiary care hospital. Adults receiving oral calcium and active vitamin D therapy, who volunteered to complete the Beck Depression Inventory BDI, and who did not have any mental disability or concomitant chronic serious disease were included. Biochemical and complication data were collected, and treatment adherence was assessed on the basis of self-reported medication use. Results: Of the 33 patients mean age 53.7  12.7 years; 78.8 female, 54.5 were non-adherent to treatment. Depressive symptoms ranged from minimal to severe, with 24.3 experiencing moderate to severe symptoms. A significant association was found between HPT etiology and depressive symptom severity p  0.011, with moderate symptoms more common in post-operative patients 34.8 vs. 0 in non-surgical cases. A weak negative correlation was observed between depressive symptom scores and highest calcium levels r  -0.359, p  0.04. Conclusions: This study emphasizes the importance of treatment goals by demonstrating the negative correlation between Ca levels and BDI scores. The high prevalence of depressive symptoms and non-adherence in patients with HPT underlines the need for tailored mental health and adherence interventions.

 Aims: Hypoparathyroidism HPT is a chronic disease characterized by low calcium levels and significant psychological and physical complications. The aim of this study was to investigate the relationship between depressive symptoms and treatment adherence in patients with HPT. Materials and Methods: This cross-sectional, observational study included patients with chronic HPT from the endocrinology clinic of a tertiary care hospital. Adults receiving oral calcium and active vitamin D therapy, who volunteered to complete the Beck Depression Inventory BDI, and who did not have any mental disability or concomitant chronic serious disease were included. Biochemical and complication data were collected, and treatment adherence was assessed on the basis of self-reported medication use. Results: Of the 33 patients mean age 53.7  12.7 years; 78.8 female, 54.5 were non-adherent to treatment. Depressive symptoms ranged from minimal to severe, with 24.3 experiencing moderate to severe symptoms. A significant association was found between HPT etiology and depressive symptom severity p  0.011, with moderate symptoms more common in post-operative patients 34.8 vs. 0 in non-surgical cases. A weak negative correlation was observed between depressive symptom scores and highest calcium levels r  -0.359, p  0.04. Conclusions: This study emphasizes the importance of treatment goals by demonstrating the negative correlation between Ca levels and BDI scores. The high prevalence of depressive symptoms and non-adherence in patients with HPT underlines the need for tailored mental health and adherence interventions.

 Aims: Hypoparathyroidism HPT is a chronic disease characterized by low calcium levels and significant psychological and physical complications. The aim of this study was to investigate the relationship between depressive symptoms and treatment adherence in patients with HPT. Materials and Methods: This cross-sectional, observational study included patients with chronic HPT from the endocrinology clinic of a tertiary care hospital. Adults receiving oral calcium and active vitamin D therapy, who volunteered to complete the Beck Depression Inventory BDI, and who did not have any mental disability or concomitant chronic serious disease were included. Biochemical and complication data were collected, and treatment adherence was assessed on the basis of self-reported medication use. Results: Of the 33 patients mean age 53.7  12.7 years; 78.8 female, 54.5 were non-adherent to treatment. Depressive symptoms ranged from minimal to severe, with 24.3 experiencing moderate to severe symptoms. A significant association was found between HPT etiology and depressive symptom severity p  0.011, with moderate symptoms more common in post-operative patients 34.8 vs. 0 in non-surgical cases. A weak negative correlation was observed between depressive symptom scores and highest calcium levels r  -0.359, p  0.04. Conclusions: This study emphasizes the importance of treatment goals by demonstrating the negative correlation between Ca levels and BDI scores. The high prevalence of depressive symptoms and non-adherence in patients with HPT underlines the need for tailored mental health and adherence interventions.

Makale detayları

The Relationship Between Depressive Symptoms and Treatment Adherence in Patients With Hypoparathyroidism

Yazarlar:

Zeynep Ece Demirbaş

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Endocrinology | Internal Diseases

Dergi:

Developments and Experiments in Health and Medicine Vol.39 Issue 1, pp.47-60

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001342378

pISSN:

3062-2948

Hypoparathyroidism

depression

hypocalcemia.

Sayı

Makale detayları

The Relationship Between Depressive Symptoms and Treatment Adherence in Patients With Hypoparathyroidism

Yazarlar: Zeynep Ece Demirbaş

Yayıncı: Dokuz Eylul University

Ana Başlıklar: Endocrinology | Internal Diseases

Dergi: Developments and Experiments in Health and Medicine Vol.39 Issue 1, pp.47-60

Belge Tipi: Makale

Yayın Tarihi: 12/2025

Belge Dili: İngilizce

Document ID (Org No.): 2001342378

pISSN: 3062-2948

Hypoparathyroidism

depression

hypocalcemia.

Sayı

Yazarlar:

Zeynep Ece Demirbaş

Yayıncı:

Dokuz Eylul University

Ana Başlıklar:

Endocrinology | Internal Diseases

Dergi:

Developments and Experiments in Health and Medicine Vol.39 Issue 1, pp.47-60

Belge Tipi:

Makale

Yayın Tarihi:

12/2025

Belge Dili:

İngilizce

Document ID (Org No.):

2001342378

pISSN:

3062-2948