Total Parenteral Nutrition-Associated Cholestasis  in Surgical Neonates

Alaeddin DİLSİZ

Makale detayları

Total Parenteral Nutrition-Associated Cholestasis in Surgical Neonates

Yazarlar:

Alaeddin DİLSİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 6, pp.689-692

Belge Tipi:

Makale

Yayın Tarihi:

5/1999

Belge Dili:

Türkçe

Document ID (Org No.):

2000757818

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

Purpose: The aim of this study was to determine the risk factors in the development of total parenteral nutrition associated cholestasis which is a significant clinical problem for pediatric surgeons.  Methods: The medical records of 54 neonates who had received total parenteral nutrition for more than two weeks were   reviewed retros pectively. Prematurity, duration of parenteral nutrition, enteral starvation, composition of the parenteral   nutrition solution, the number of septic episodes and the presence of jejunostomy were evaluated as risk factors. The results were analyzed by dividing the patients into two groups, based on conjugated plasma bilirubin levels (greater or less than 2 mg/dl) during total parenteral nutrition.  Results: There were significant differences between the two groups with respect to birth weight, gestational age at birth, duration of enteral starvation, the number of septic episodes and the presence of jejunostomy.  Conclusion: The interruption of enterohepatic circulation (by enteral starvation, IV administration of nutrients and   the presence of jejunostomy) is one of the most important factors in the development of total parenteral nutrition -associated cholestasis.

 

Purpose: The aim of this study was to determine the risk factors in the development of total parenteral nutrition associated cholestasis which is a significant clinical problem for pediatric surgeons.  Methods: The medical records of 54 neonates who had received total parenteral nutrition for more than two weeks were   reviewed retros pectively. Prematurity, duration of parenteral nutrition, enteral starvation, composition of the parenteral   nutrition solution, the number of septic episodes and the presence of jejunostomy were evaluated as risk factors. The results were analyzed by dividing the patients into two groups, based on conjugated plasma bilirubin levels (greater or less than 2 mg/dl) during total parenteral nutrition.  Results: There were significant differences between the two groups with respect to birth weight, gestational age at birth, duration of enteral starvation, the number of septic episodes and the presence of jejunostomy.  Conclusion: The interruption of enterohepatic circulation (by enteral starvation, IV administration of nutrients and   the presence of jejunostomy) is one of the most important factors in the development of total parenteral nutrition -associated cholestasis.

Makale detayları

Total Parenteral Nutrition-Associated Cholestasis in Surgical Neonates

Yazarlar:

Alaeddin DİLSİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 6, pp.689-692

Belge Tipi:

Makale

Yayın Tarihi:

5/1999

Belge Dili:

Türkçe

Document ID (Org No.):

2000757818

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Total parenteral nutrition

cholestasis

enterohepatic circulation.

Sayı

Makale detayları

Total Parenteral Nutrition-Associated Cholestasis in Surgical Neonates

Yazarlar: Alaeddin DİLSİZ

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 1999 Vol.29 Issue 6, pp.689-692

Belge Tipi: Makale

Yayın Tarihi: 5/1999

Belge Dili: Türkçe

Document ID (Org No.): 2000757818

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Total parenteral nutrition

cholestasis

enterohepatic circulation.

Sayı

Yazarlar:

Alaeddin DİLSİZ

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 6, pp.689-692

Belge Tipi:

Makale

Yayın Tarihi:

5/1999

Belge Dili:

Türkçe

Document ID (Org No.):

2000757818

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144