Serum procalcitonin and C-reactive protein kinetics as indicators of treatmentoutcome in hospitalized patients with community-acquired pneumonia

Mehmet Sezai TAŞBAKAN; Canan GÜNDÜZ; Abdullah SAYINER; Aykut ÇİLLİ; Burcu Çelenk KARABOĞA; Ayşin Şakar COŞKUN; Feride Durmaz YAMAN; Oğuz KILINÇ; Öznur Kiliç SOYLAR

Makale detayları

Serum procalcitonin and C-reactive protein kinetics as indicators of treatmentoutcome in hospitalized patients with community-acquired pneumonia

Yazarlar:

Mehmet Sezai TAŞBAKAN | Canan GÜNDÜZ | Abdullah SAYINER | Aykut ÇİLLİ | Burcu Çelenk KARABOĞA | Ayşin Şakar COŞKUN | Feride Durmaz YAMAN | Oğuz KILINÇ | Öznur Kiliç SOYLAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1422-1427

Belge Tipi:

Makale

Yayın Tarihi:

9/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000751824

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: There has been growing interest in the use of serum procalcitonin (PCT) and C-reactive protein (CRP) in patients with community-acquired pneumonia (CAP). The aim of this study was to investigate whether an assessment of fever, leukocyte count, and serum CRP and PCT levels on admission and during follow-up (day 3) provides any information about the clinical outcome in hospitalized patients with CAP.  Materials and methods: Patients with a diagnosis of CAP who were admitted to and followed at four university hospitals were evaluated retrospectively using the Turkish Thoracic Society Pneumonia Database.   Results: A total of 103 hospitalized CAP patients (57 males, mean age: 61.5 ± 16.7 years) were enrolled in the study. Treatment failure (TF) was observed in 20 patients (19.4%). Pneumonia Severity Index scores, serum CRP levels, and PCT levels on admission were significantly higher in the TF group. There were significant decreases in CRP and PCT levels between admission day and day 3 in the treatment success group.   Conclusion: In patients with CAP, the body temperature and leukocyte count on admission do not predict outcome. Monitoring levels of CRP and PCT may be useful as a predictor of treatment outcome.

Makale detayları

Serum procalcitonin and C-reactive protein kinetics as indicators of treatmentoutcome in hospitalized patients with community-acquired pneumonia

Yazarlar: Mehmet Sezai TAŞBAKAN | Canan GÜNDÜZ | Abdullah SAYINER | Aykut ÇİLLİ | Burcu Çelenk KARABOĞA | Ayşin Şakar COŞKUN | Feride Durmaz YAMAN | Oğuz KILINÇ | Öznur Kiliç SOYLAR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1422-1427

Belge Tipi: Makale

Yayın Tarihi: 9/2016

Belge Dili: Türkçe

Document ID (Org No.): 2000751824

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Mehmet Sezai TAŞBAKAN | Canan GÜNDÜZ | Abdullah SAYINER | Aykut ÇİLLİ | Burcu Çelenk KARABOĞA | Ayşin Şakar COŞKUN | Feride Durmaz YAMAN | Oğuz KILINÇ | Öznur Kiliç SOYLAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 5, pp.1422-1427

Belge Tipi:

Makale

Yayın Tarihi:

9/2016

Belge Dili:

Türkçe

Document ID (Org No.):

2000751824

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144