Early graft dysfunction and mortality rate in marginal donor liver transplantation

Pınar SARKUT; Barış GÜLCÜ; Remzi İŞÇİMEN; Murat KIYICI; Gürkan TÜRKER

Makale detayları

Early graft dysfunction and mortality rate in marginal donor liver transplantation

Yazarlar:

Pınar SARKUT | Barış GÜLCÜ | Remzi İŞÇİMEN | Murat KIYICI | Gürkan TÜRKER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 4, pp.709-711

Belge Tipi:

Makale

Yayın Tarihi:

5/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753204

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

To determine the effect of marginal donor livers on mortality and graft survival in liver transplantation (LT) recipients.   Materials and methods: Donors with any 1 of following were considered marginal donors: age =>65 years, sodium level =>165 mmol/L and cold ischemia time =>12 h. Donors were classified according to the donor risk index (DRI) 1.7. The transplant recipients' model for end-stage liver disease (MELD) scores were considered low if 20. Early graft dysfunction (EGD) and mortality rate were evaluated.   Results: During the study period 47 patients underwent cadaveric LT. The mean age of the donors and recipients was 45 years (range: 5¬-72 years) and 46 years (range: 4-66 years), respectively. In all, there were 15 marginal donors and 18 donors with a DRI >1.7. In total, 4 LT patients that received livers from marginal donors and 5 that received livers from donors with a DRI =>1.7 had EGD. Among the recipients of marginal livers, 5 died, versus 4 of the recipients of standard livers. There was no significant difference in EGD or mortality rate between the patients that received livers from marginal donors or those with a DRI =>1.7 and patients that received standard donor livers.   Conclusion: Marginal and DRI =>1.7 donors negatively affected LT outcomes, but not significantly.

 

To determine the effect of marginal donor livers on mortality and graft survival in liver transplantation (LT) recipients.   Materials and methods: Donors with any 1 of following were considered marginal donors: age =>65 years, sodium level =>165 mmol/L and cold ischemia time =>12 h. Donors were classified according to the donor risk index (DRI) 1.7. The transplant recipients' model for end-stage liver disease (MELD) scores were considered low if 20. Early graft dysfunction (EGD) and mortality rate were evaluated.   Results: During the study period 47 patients underwent cadaveric LT. The mean age of the donors and recipients was 45 years (range: 5¬-72 years) and 46 years (range: 4-66 years), respectively. In all, there were 15 marginal donors and 18 donors with a DRI >1.7. In total, 4 LT patients that received livers from marginal donors and 5 that received livers from donors with a DRI =>1.7 had EGD. Among the recipients of marginal livers, 5 died, versus 4 of the recipients of standard livers. There was no significant difference in EGD or mortality rate between the patients that received livers from marginal donors or those with a DRI =>1.7 and patients that received standard donor livers.   Conclusion: Marginal and DRI =>1.7 donors negatively affected LT outcomes, but not significantly.

Makale detayları

Early graft dysfunction and mortality rate in marginal donor liver transplantation

Yazarlar:

Pınar SARKUT | Barış GÜLCÜ | Remzi İŞÇİMEN | Murat KIYICI | Gürkan TÜRKER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 4, pp.709-711

Belge Tipi:

Makale

Yayın Tarihi:

5/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753204

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Marginal donor

cadaveric liver transplantation

early graft dysfunction

mortality

Sayı

Makale detayları

Early graft dysfunction and mortality rate in marginal donor liver transplantation

Yazarlar: Pınar SARKUT | Barış GÜLCÜ | Remzi İŞÇİMEN | Murat KIYICI | Gürkan TÜRKER

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2014 Vol.44 Issue 4, pp.709-711

Belge Tipi: Makale

Yayın Tarihi: 5/2014

Belge Dili: Türkçe

Document ID (Org No.): 2000753204

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Marginal donor

cadaveric liver transplantation

early graft dysfunction

mortality

Sayı

Yazarlar:

Pınar SARKUT | Barış GÜLCÜ | Remzi İŞÇİMEN | Murat KIYICI | Gürkan TÜRKER

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2014 Vol.44 Issue 4, pp.709-711

Belge Tipi:

Makale

Yayın Tarihi:

5/2014

Belge Dili:

Türkçe

Document ID (Org No.):

2000753204

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144