Does vitreous galactin-3, copeptin and retina binding protein-4 concentrations change in diabetic retinopathy?

Şerife Gülhan Konuk; Raşit Kılıç; Merve Çatak; Alper Güneş; Muzaffer Katar

Makale detayları

Does vitreous galactin-3, copeptin and retina binding protein-4 concentrations change in diabetic retinopathy?

Yazarlar:

Şerife Gülhan Konuk | Raşit Kılıç | Merve Çatak | Alper Güneş | Muzaffer Katar

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göz Hastalıkları | Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Anatolian Current Medical Journal Vol.5 Issue 4, pp.411-415

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302542

pISSN:

2718-0115

Anahtar kelimeler:

Özet:

 Aims: This study aimed to investigate whether the concentrations of Galactin-3 G-3, Copeptin CP and Retina Binding Protein-4 RBP-4 are affected in the vitreous humor of patients with diabetic retinopathy DR. Methods: Thirty-six patients with diabetes mellitus DM were included in the study, consisting of 10 patients without DR and 26 patients with proliferative diabetic retinopathy PDR. The control group comprised 15 patients who underwent vitrectomy for epiretinal membrane and macular hole surgeries. Vitreous CP, G-3, and RBP-4 concentrations were examined using the enzyme-linked immunosorbent assay ELISA method. The groups were compared internally Results: We did not observe any significant differences in the concentrations of G-3, CP and RBP-4 in the vitreous humor between diabetic patients and the control group p0.56, p0.65 and p0.11, respectively. When comparing vitreous samples of diabetic subgroups with and without DR findings to the control group, no significant differences were detected p0.51, p0.66, and p0.19, respectively. Conclusion: Our results indicate that the concentrations of G-3, CP, and RBP-4 in the vitreous humor remain unchanged in both diabetic patients and those with proliferative diabetic retinopathy DRP.

 Aims: This study aimed to investigate whether the concentrations of Galactin-3 G-3, Copeptin CP and Retina Binding Protein-4 RBP-4 are affected in the vitreous humor of patients with diabetic retinopathy DR. Methods: Thirty-six patients with diabetes mellitus DM were included in the study, consisting of 10 patients without DR and 26 patients with proliferative diabetic retinopathy PDR. The control group comprised 15 patients who underwent vitrectomy for epiretinal membrane and macular hole surgeries. Vitreous CP, G-3, and RBP-4 concentrations were examined using the enzyme-linked immunosorbent assay ELISA method. The groups were compared internally Results: We did not observe any significant differences in the concentrations of G-3, CP and RBP-4 in the vitreous humor between diabetic patients and the control group p0.56, p0.65 and p0.11, respectively. When comparing vitreous samples of diabetic subgroups with and without DR findings to the control group, no significant differences were detected p0.51, p0.66, and p0.19, respectively. Conclusion: Our results indicate that the concentrations of G-3, CP, and RBP-4 in the vitreous humor remain unchanged in both diabetic patients and those with proliferative diabetic retinopathy DRP.

 Aims: This study aimed to investigate whether the concentrations of Galactin-3 G-3, Copeptin CP and Retina Binding Protein-4 RBP-4 are affected in the vitreous humor of patients with diabetic retinopathy DR. Methods: Thirty-six patients with diabetes mellitus DM were included in the study, consisting of 10 patients without DR and 26 patients with proliferative diabetic retinopathy PDR. The control group comprised 15 patients who underwent vitrectomy for epiretinal membrane and macular hole surgeries. Vitreous CP, G-3, and RBP-4 concentrations were examined using the enzyme-linked immunosorbent assay ELISA method. The groups were compared internally Results: We did not observe any significant differences in the concentrations of G-3, CP and RBP-4 in the vitreous humor between diabetic patients and the control group p0.56, p0.65 and p0.11, respectively. When comparing vitreous samples of diabetic subgroups with and without DR findings to the control group, no significant differences were detected p0.51, p0.66, and p0.19, respectively. Conclusion: Our results indicate that the concentrations of G-3, CP, and RBP-4 in the vitreous humor remain unchanged in both diabetic patients and those with proliferative diabetic retinopathy DRP.

 Aims: This study aimed to investigate whether the concentrations of Galactin-3 G-3, Copeptin CP and Retina Binding Protein-4 RBP-4 are affected in the vitreous humor of patients with diabetic retinopathy DR. Methods: Thirty-six patients with diabetes mellitus DM were included in the study, consisting of 10 patients without DR and 26 patients with proliferative diabetic retinopathy PDR. The control group comprised 15 patients who underwent vitrectomy for epiretinal membrane and macular hole surgeries. Vitreous CP, G-3, and RBP-4 concentrations were examined using the enzyme-linked immunosorbent assay ELISA method. The groups were compared internally Results: We did not observe any significant differences in the concentrations of G-3, CP and RBP-4 in the vitreous humor between diabetic patients and the control group p0.56, p0.65 and p0.11, respectively. When comparing vitreous samples of diabetic subgroups with and without DR findings to the control group, no significant differences were detected p0.51, p0.66, and p0.19, respectively. Conclusion: Our results indicate that the concentrations of G-3, CP, and RBP-4 in the vitreous humor remain unchanged in both diabetic patients and those with proliferative diabetic retinopathy DRP.

Makale detayları

Does vitreous galactin-3, copeptin and retina binding protein-4 concentrations change in diabetic retinopathy?

Yazarlar:

Şerife Gülhan Konuk | Raşit Kılıç | Merve Çatak | Alper Güneş | Muzaffer Katar

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göz Hastalıkları | Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Anatolian Current Medical Journal Vol.5 Issue 4, pp.411-415

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302542

pISSN:

2718-0115

Copeptin

Galactin-3

Retina Binding Protein-4

Diabetes mellitus

Diabetic retinopathy

Sayı

Makale detayları

Does vitreous galactin-3, copeptin and retina binding protein-4 concentrations change in diabetic retinopathy?

Yazarlar: Şerife Gülhan Konuk | Raşit Kılıç | Merve Çatak | Alper Güneş | Muzaffer Katar

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Göz Hastalıkları | Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi: Anatolian Current Medical Journal Vol.5 Issue 4, pp.411-415

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001302542

pISSN: 2718-0115

Copeptin

Galactin-3

Retina Binding Protein-4

Diabetes mellitus

Diabetic retinopathy

Sayı

Yazarlar:

Şerife Gülhan Konuk | Raşit Kılıç | Merve Çatak | Alper Güneş | Muzaffer Katar

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Göz Hastalıkları | Göz Hastalıkları ve Göz Ölçümleri (Diğer)

Dergi:

Anatolian Current Medical Journal Vol.5 Issue 4, pp.411-415

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302542

pISSN:

2718-0115