Investigation of the effects of CO2 insufflation on blood gas values during laparoscopic procedures in pigs

Özlem GÜZEL; Dilek OLGUN ERDİKMEN; Didar AYDIN; Zihni MUTLU; Esma YILDAR

Makale detayları

Investigation of the effects of CO2 insufflation on blood gas values during laparoscopic procedures in pigs

Yazarlar:

Özlem GÜZEL | Dilek OLGUN ERDİKMEN | Didar AYDIN | Zihni MUTLU | Esma YILDAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 2, pp.183-187

Belge Tipi:

Makale

Yayın Tarihi:

1/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000766991

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Anahtar kelimeler:

Özet:

 

Due to the fact that they produce less post-operative pain and shorter hospitalisation times, laparoscopic surgery procedures are more widely used than many traditional open surgical methods. However, the carbon dioxide gas used to visualise the surgical site during the procedure causes complications such as an increase in the blood CO2 level and acidosis. In the present study, 12 male pigs were used. Sedation was achieved via intramuscular injection of xylazine at a dose of 2 mg/kg and anaesthesia induction was done via slow intravenous injection of ketamine HCl at a dose of 2 mg/kg. Following endotracheal intubation, general anaesthesia was maintained using isoflurane. Blood samples were collected from the retrobulbar plexus immediately before CO2 pneumoperitoneum (T0) and 30 min after insufflation (T1). Cases were evaluated with respect to pH, pCO2, HCO-3, and SpO2 levels. The findings obtained revealed that there was a statistically significant difference between T0 and T1 measurement times with respect to pCO2 and HCO-3 although there were no significant differences between the other evaluated parameters. As a result, it has been demonstrated that carbon dioxide pneumoperitoneum in laparoscopic surgery increases blood CO2 levels. Careful anaesthesia, endotracheal intubation, and 100% O2 inhalation throughout anaesthesia, however, can compensate for this increase. Consequently, with the preservation of blood pH and the stabilisation of pO2 levels, laparoscopic interventions can be performed without endangering the patient's life.

 

Due to the fact that they produce less post-operative pain and shorter hospitalisation times, laparoscopic surgery procedures are more widely used than many traditional open surgical methods. However, the carbon dioxide gas used to visualise the surgical site during the procedure causes complications such as an increase in the blood CO2 level and acidosis. In the present study, 12 male pigs were used. Sedation was achieved via intramuscular injection of xylazine at a dose of 2 mg/kg and anaesthesia induction was done via slow intravenous injection of ketamine HCl at a dose of 2 mg/kg. Following endotracheal intubation, general anaesthesia was maintained using isoflurane. Blood samples were collected from the retrobulbar plexus immediately before CO2 pneumoperitoneum (T0) and 30 min after insufflation (T1). Cases were evaluated with respect to pH, pCO2, HCO-3, and SpO2 levels. The findings obtained revealed that there was a statistically significant difference between T0 and T1 measurement times with respect to pCO2 and HCO-3 although there were no significant differences between the other evaluated parameters. As a result, it has been demonstrated that carbon dioxide pneumoperitoneum in laparoscopic surgery increases blood CO2 levels. Careful anaesthesia, endotracheal intubation, and 100% O2 inhalation throughout anaesthesia, however, can compensate for this increase. Consequently, with the preservation of blood pH and the stabilisation of pO2 levels, laparoscopic interventions can be performed without endangering the patient's life.

Makale detayları

Investigation of the effects of CO2 insufflation on blood gas values during laparoscopic procedures in pigs

Yazarlar:

Özlem GÜZEL | Dilek OLGUN ERDİKMEN | Didar AYDIN | Zihni MUTLU | Esma YILDAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 2, pp.183-187

Belge Tipi:

Makale

Yayın Tarihi:

1/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000766991

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128

Key words: Laparoscopy

carbon dioxide

blood gas

pig

Sayı

Makale detayları

Investigation of the effects of CO2 insufflation on blood gas values during laparoscopic procedures in pigs

Yazarlar: Özlem GÜZEL | Dilek OLGUN ERDİKMEN | Didar AYDIN | Zihni MUTLU | Esma YILDAR

Yayıncı: TUBITAK

Dergi: Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 2, pp.183-187

Belge Tipi: Makale

Yayın Tarihi: 1/2012

Belge Dili: Türkçe

Document ID (Org No.): 2000766991

Sıklık: İki Aylık

eISSN: 1303-6181

pISSN: 1300-0128

Key words: Laparoscopy

carbon dioxide

blood gas

pig

Sayı

Yazarlar:

Özlem GÜZEL | Dilek OLGUN ERDİKMEN | Didar AYDIN | Zihni MUTLU | Esma YILDAR

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Veterinary and Animal Sciences 2012 Vol.36 Issue 2, pp.183-187

Belge Tipi:

Makale

Yayın Tarihi:

1/2012

Belge Dili:

Türkçe

Document ID (Org No.):

2000766991

Sıklık:

İki Aylık

eISSN:

1303-6181

pISSN:

1300-0128