Factors Associated with the Progression of Aortic Aneurysms: A Single-Center Experience

Hande İştar; Buğra Harmandar; Burak Can Depboylu; Serkan Yazman; Fulden Cantaş Türkiş

Makale detayları

Factors Associated with the Progression of Aortic Aneurysms: A Single-Center Experience

Yazarlar:

Hande İştar | Buğra Harmandar | Burak Can Depboylu | Serkan Yazman | Fulden Cantaş Türkiş

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325380

pISSN:

2148-8118

Anahtar kelimeler:

Özet:

 Aortic aneurysms AA have a significant mortality rate in population. We aimed to identify the etiologic factors associated with thoracic aortic aneurysms TAAs and abdominal aortic aneurysms AAAs. Our study included 181 patients; 98 patients diagnosed with TAA or AAA made up the aortic aneurysm AA group, 83 patients without either condition made up the control group. Within the AA group, 72.4 of the patients were male, the patients had been diagnosed with TAA and AAA in ratio of 57.1 and 42.9 respectively. All AA group patients had an aortic diameter in range from 41 to 108 mm. Initial serum biochemical measures, two consecutive computed tomography angiography measurements were recorded, the enlargement rate per year for the aorta was calculated for all. The mean age in the AA group was 62.8913.55 compared to 68.1011.69 in the control group p0.007, higher ratio for hypertension p0.021. TAA patients had a higher AST level p0.016 and platelet counts p0.010 compared to control group. AAA patients had a higher mean neutrophillymphocyte ratio NLR p0.044 compared to control group. Among the patients with AAA, 90.5  were male. Smoking was more prevalent in the abdominal AA group p0.08. An enlargement rate of more than 1 cmyear was detected in 25 of the patients with TAA and in 75 of the patients with AAA. TAA was associated with higher AST levels and higher platelet counts than were in the AAA group, whereas AAA showed strong relationships with male gender and smoking.

 Aortic aneurysms AA have a significant mortality rate in population. We aimed to identify the etiologic factors associated with thoracic aortic aneurysms TAAs and abdominal aortic aneurysms AAAs. Our study included 181 patients; 98 patients diagnosed with TAA or AAA made up the aortic aneurysm AA group, 83 patients without either condition made up the control group. Within the AA group, 72.4 of the patients were male, the patients had been diagnosed with TAA and AAA in ratio of 57.1 and 42.9 respectively. All AA group patients had an aortic diameter in range from 41 to 108 mm. Initial serum biochemical measures, two consecutive computed tomography angiography measurements were recorded, the enlargement rate per year for the aorta was calculated for all. The mean age in the AA group was 62.8913.55 compared to 68.1011.69 in the control group p0.007, higher ratio for hypertension p0.021. TAA patients had a higher AST level p0.016 and platelet counts p0.010 compared to control group. AAA patients had a higher mean neutrophillymphocyte ratio NLR p0.044 compared to control group. Among the patients with AAA, 90.5  were male. Smoking was more prevalent in the abdominal AA group p0.08. An enlargement rate of more than 1 cmyear was detected in 25 of the patients with TAA and in 75 of the patients with AAA. TAA was associated with higher AST levels and higher platelet counts than were in the AAA group, whereas AAA showed strong relationships with male gender and smoking.

 Aortic aneurysms AA have a significant mortality rate in population. We aimed to identify the etiologic factors associated with thoracic aortic aneurysms TAAs and abdominal aortic aneurysms AAAs. Our study included 181 patients; 98 patients diagnosed with TAA or AAA made up the aortic aneurysm AA group, 83 patients without either condition made up the control group. Within the AA group, 72.4 of the patients were male, the patients had been diagnosed with TAA and AAA in ratio of 57.1 and 42.9 respectively. All AA group patients had an aortic diameter in range from 41 to 108 mm. Initial serum biochemical measures, two consecutive computed tomography angiography measurements were recorded, the enlargement rate per year for the aorta was calculated for all. The mean age in the AA group was 62.8913.55 compared to 68.1011.69 in the control group p0.007, higher ratio for hypertension p0.021. TAA patients had a higher AST level p0.016 and platelet counts p0.010 compared to control group. AAA patients had a higher mean neutrophillymphocyte ratio NLR p0.044 compared to control group. Among the patients with AAA, 90.5  were male. Smoking was more prevalent in the abdominal AA group p0.08. An enlargement rate of more than 1 cmyear was detected in 25 of the patients with TAA and in 75 of the patients with AAA. TAA was associated with higher AST levels and higher platelet counts than were in the AAA group, whereas AAA showed strong relationships with male gender and smoking.

 Aort anevrizmaları AA, yetişkinlerde önemli mortalite sebebidir. Çalışmamızda, torasik aort anevrizması TAA ve abdominal aort anevrizması AAA ile ilişkili etyolojik faktörleri araştırmayı amaçladık. Çalışmamız 181 bireyi 98i TAA ve AAA tanılı, 83ü kontrol grubu içermektedir. Aort anevrizma AA grubunda 72.4ü erkekti. AA grubunda 57.1i TAA, 42.9u AAA tanılıydı. Aorta çapı 41-108 mm aralığında olanlar AA grup içine alındı. İnisiyal serum biyokimya değerleri ve 2 ardışık bilgisayarlı tomografi anjiografi ölçümü değerlendirildi ve her birey için yıllık aort çapı genişlemesi ölçüldü. AA grup ve kontrol grubu ortalama yaşı sırasıyla 62.8913.55 ve 68.1011.69 idi p0.007, hipertansiyon oranı p0.021 daha yüksekti. TAA grubu daha yüksek AST p0.016 ve trombosit değerlerine p0.010 sahipti. AAA grubunda ise yüksek nötrofillenfosit oranı NLR p0.044 mevcuttu. AAA grubunda erkek oranı 90.5ti. Sigara kullanımı AAA grubunda daha belirgindi p0.08. Bir cmyıldan daha hızlı anevrizma büyüme hızı oranı, TAA ve AAA gruplarında sırasıyla 25 ve 75 idi. TAA ile yüksek AST ve yüksek trombosit değeri arasında korelasyon mevcuttu. AAA ise erkek cinsiyet, sigara kullanımı ile yakından ilişkili bulundu.

Makale detayları

Factors Associated with the Progression of Aortic Aneurysms: A Single-Center Experience

Yazarlar:

Hande İştar | Buğra Harmandar | Burak Can Depboylu | Serkan Yazman | Fulden Cantaş Türkiş

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325380

pISSN:

2148-8118

Abdominal Aortic Aneurysm

ALT

AST

Neutrophil/Lymphocyte Ratio

Thoracic Aortic AneurysmAbdominal Aort Anevrizması

ALT

AST

Nötrofil/Lenfosit Oranı

Torasik Aort Anevrizması

Sayı

Makale detayları

Yazarlar: Hande İştar | Buğra Harmandar | Burak Can Depboylu | Serkan Yazman | Fulden Cantaş Türkiş

Yayıncı: Mugla Sitki Kocman University

Ana Başlıklar: Klinik Tıp Bilimleri (Diğer)

Dergi: Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.47-52

Belge Tipi: Makale

Yayın Tarihi: 8/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001325380

pISSN: 2148-8118

Sayı

Yazarlar:

Hande İştar | Buğra Harmandar | Burak Can Depboylu | Serkan Yazman | Fulden Cantaş Türkiş

Yayıncı:

Mugla Sitki Kocman University

Ana Başlıklar:

Klinik Tıp Bilimleri (Diğer)

Dergi:

Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi Vol.11 Issue 2, pp.47-52

Belge Tipi:

Makale

Yayın Tarihi:

8/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001325380

pISSN:

2148-8118