Study of the interaction between glucosamine hydrochloride and sodium dodecylsulphate micelles using conductometric, isothermal calorimetry, zeta-potential titrations, and NMR NOESY

Marcos Roberto Abreu ALVES; Luciano Sindra VIRTUOSO

doi:https://doi.org/10.3906/kim-1306-22

Makale detayları

Study of the interaction between glucosamine hydrochloride and sodium dodecylsulphate micelles using conductometric, isothermal calorimetry, zeta-potential titrations, and NMR NOESY

Yazarlar:

Marcos Roberto Abreu ALVES | Luciano Sindra VIRTUOSO

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2014 Vol.38 Issue 2, pp.248-259

Belge Tipi:

Makale

Yayın Tarihi:

5/2014

Belge Dili:

İngilizce

Document ID (Org No.):

2000727211

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1306-22

Özet:

 

The aim of this work was to investigate the influence of an  anti-inflammatory agent, the bulky counterion named glucosamine (Gl+),  in sodium dodecylsulphate (SDS) in 2 ways: 1) by titration of SDS solutions  with different concentrations of Gl+; and 2) by titration of Gl+  with SDS solution with concentration close to the critical micellar  concentration (cmc) (7.7 mM). In procedure 1, micellisation study by  isothermal titration calorimetry (ITC) showed that the increase in Gl+  concentration reduces the cmc and the micellisation enthalpy. Increasing of  the micellisation entropy was also observed, suggesting desolvation of  micellar structures as a consequence of electrostatic attraction with  Gl+ ions. In procedure 2, titration of Gl+ with SDS solution at 7.7  mM showed the existence of 3 distinct ranges of glucosamine/SDS  concentrations, which were attributed to I) Gl+ inducing micellisation,  II) neutralisation of the micelles, and III) competition between the ions  themselves in the micellar surface.

 

The aim of this work was to investigate the influence of an  anti-inflammatory agent, the bulky counterion named glucosamine (Gl+),  in sodium dodecylsulphate (SDS) in 2 ways: 1) by titration of SDS solutions  with different concentrations of Gl+; and 2) by titration of Gl+  with SDS solution with concentration close to the critical micellar  concentration (cmc) (7.7 mM). In procedure 1, micellisation study by  isothermal titration calorimetry (ITC) showed that the increase in Gl+  concentration reduces the cmc and the micellisation enthalpy. Increasing of  the micellisation entropy was also observed, suggesting desolvation of  micellar structures as a consequence of electrostatic attraction with  Gl+ ions. In procedure 2, titration of Gl+ with SDS solution at 7.7  mM showed the existence of 3 distinct ranges of glucosamine/SDS  concentrations, which were attributed to I) Gl+ inducing micellisation,  II) neutralisation of the micelles, and III) competition between the ions  themselves in the micellar surface.

Makale detayları

Study of the interaction between glucosamine hydrochloride and sodium dodecylsulphate micelles using conductometric, isothermal calorimetry, zeta-potential titrations, and NMR NOESY

Yazarlar: Marcos Roberto Abreu ALVES | Luciano Sindra VIRTUOSO

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2014 Vol.38 Issue 2, pp.248-259

Belge Tipi: Makale

Yayın Tarihi: 5/2014

Belge Dili: İngilizce

Document ID (Org No.): 2000727211

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

DOI: https://doi.org/10.3906/kim-1306-22

Sayı

Yazarlar:

Marcos Roberto Abreu ALVES | Luciano Sindra VIRTUOSO

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2014 Vol.38 Issue 2, pp.248-259

Belge Tipi:

Makale

Yayın Tarihi:

5/2014

Belge Dili:

İngilizce

Document ID (Org No.):

2000727211

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

DOI:

https://doi.org/10.3906/kim-1306-22