Evaluation of the Effect of Age-Related Macular Degeneration Type And Stage on the Risk of Parkinson’s Disease

Erdoğan Yaşar; Ugur Gürlevik; Mustafa Değer Bilgeç; Muzaffer Güneş

Makale detayları

Evaluation of the Effect of Age-Related Macular Degeneration Type And Stage on the Risk of Parkinson’s Disease

Yazarlar:

Erdoğan Yaşar | Ugur Gürlevik | Mustafa Değer Bilgeç | Muzaffer Güneş

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Göz Hastalıkları

Dergi:

Osmangazi Tıp Dergisi Vol.46 Issue 3, pp.422-428

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001313504

pISSN:

1305-4953

Anahtar kelimeler:

Özet:

 The aim of the study was to investigate the distance between Parkinsons Disease PD and Age-Related Macular Degeneration AMD type and stage.. Our prospective study, the dry-type AMD group consisted of 296 patients with early and 284 patients with late-stage. The neovascular AMD group included 285 early and 277 late-stage patients. The control group consisted of 300 patients. AMD patients were grouped as dry and neovascular type and early and late stage. The patients were questioned about the use of drugs for PD, and the use was recorded as having the disease. If any of the complaints seen in the PD were present, the patient was referred to a neurologist. PD was detected in 1 of the control group and 4.6 in the neovascular type AMD group, and this difference was significant p:0.04. This difference was present in both the early 4.5 and late-stage 4.6  p:0.04, p:0.04. PD was determined 3.78 times greater among neovascular AMD patientsp:0.03, and significant association was present in both early 3.72 times and late-stage 3.82 times p:0.03, p:0.03. In the dry-type AMD group 2.7 PD was detected and there was no statistical difference p0.05. This difference was not significant in the early stage 2.3 or late-stage 2.8 and also there was no association with dry-type AMD p0.05. Also, unilateral and bilateral involvement in AMD was not associated with PD p0.05. Our study revealed the association between both early and late neovascular AMD and PD. However, any significant relationship was not detected in terms of both unilateral and bilateral involvement.

 The aim of the study was to investigate the distance between Parkinsons Disease PD and Age-Related Macular Degeneration AMD type and stage.. Our prospective study, the dry-type AMD group consisted of 296 patients with early and 284 patients with late-stage. The neovascular AMD group included 285 early and 277 late-stage patients. The control group consisted of 300 patients. AMD patients were grouped as dry and neovascular type and early and late stage. The patients were questioned about the use of drugs for PD, and the use was recorded as having the disease. If any of the complaints seen in the PD were present, the patient was referred to a neurologist. PD was detected in 1 of the control group and 4.6 in the neovascular type AMD group, and this difference was significant p:0.04. This difference was present in both the early 4.5 and late-stage 4.6  p:0.04, p:0.04. PD was determined 3.78 times greater among neovascular AMD patientsp:0.03, and significant association was present in both early 3.72 times and late-stage 3.82 times p:0.03, p:0.03. In the dry-type AMD group 2.7 PD was detected and there was no statistical difference p0.05. This difference was not significant in the early stage 2.3 or late-stage 2.8 and also there was no association with dry-type AMD p0.05. Also, unilateral and bilateral involvement in AMD was not associated with PD p0.05. Our study revealed the association between both early and late neovascular AMD and PD. However, any significant relationship was not detected in terms of both unilateral and bilateral involvement.

 The aim of the study was to investigate the distance between Parkinsons Disease PD and Age-Related Macular Degeneration AMD type and stage.. Our prospective study, the dry-type AMD group consisted of 296 patients with early and 284 patients with late-stage. The neovascular AMD group included 285 early and 277 late-stage patients. The control group consisted of 300 patients. AMD patients were grouped as dry and neovascular type and early and late stage. The patients were questioned about the use of drugs for PD, and the use was recorded as having the disease. If any of the complaints seen in the PD were present, the patient was referred to a neurologist. PD was detected in 1 of the control group and 4.6 in the neovascular type AMD group, and this difference was significant p:0.04. This difference was present in both the early 4.5 and late-stage 4.6  p:0.04, p:0.04. PD was determined 3.78 times greater among neovascular AMD patientsp:0.03, and significant association was present in both early 3.72 times and late-stage 3.82 times p:0.03, p:0.03. In the dry-type AMD group 2.7 PD was detected and there was no statistical difference p0.05. This difference was not significant in the early stage 2.3 or late-stage 2.8 and also there was no association with dry-type AMD p0.05. Also, unilateral and bilateral involvement in AMD was not associated with PD p0.05. Our study revealed the association between both early and late neovascular AMD and PD. However, any significant relationship was not detected in terms of both unilateral and bilateral involvement.

 Çalışmamızın amacı Parkinson Hastalığı PD ile Yaşa Bağlı Makula Dejenerasyonu YBMD tipi ve evresi arasındaki ilişkiyi araştırmak idi.. Prospektif çalışmamızda kuru tip YBMD grubu 296 erken evre ve 284 geç evre hastadan oluşuyordu. Neovasküler AMD grubu 285 erken ve 277 geç evre hastayı içeriyordu. Kontrol grubu 300 hastadan oluşuyordu. YBMD hastaları kuru ve neovasküler tip ile erken ve geç evre olarak gruplandırıldı. Hastalara PH için ilaç kullanımı sorgulandı ve kullananların hastalıklı olduğu kaydedildi. PHde görülen şikayetlerden herhangi birinin mevcut olması durumunda hasta nöroloji uzmanına yönlendirildi. Kontrol grubunun 1inde, neovasküler tip YBMD grubunda ise 4,6 oranında PH saptandı ve bu fark anlamlıydı p:0,04. Bu fark hem erken 4,5 hem de geç dönemde 4,6 mevcuttu p:0,04, p:0,04. Neovasküler YBMD hastalarında PD 3,78 kat daha fazla saptandı p:0,03, hem erken 3,72 kat hem de geç dönemde 3,82 kat anlamlı ilişki mevcuttu p:0,03, p:0,03. Kuru tip YBMD grubunda 2,7 PD tespit edildi ve istatistiksel olarak fark saptanmadı p0,05. Bu fark erken dönemde 2,3 ve geç dönemde 2,8 anlamlı bulunmazken, kuru tip YBMD ile de ilişki saptanmadı p0,05. Ayrıca YBMDnin tek taraflı ve iki taraflı tutulumu PH ile ilişkili değildi p0,05. Çalışmamız hem erken hem de geç neovasküler YBMD ile PD arasındaki ilişkiyi ortaya çıkardı. Ancak hem tek taraflı hem de iki taraflı tutulum açısından anlamlı bir ilişki saptanmadı.

Makale detayları

Evaluation of the Effect of Age-Related Macular Degeneration Type And Stage on the Risk of Parkinson’s Disease

Yazarlar:

Erdoğan Yaşar | Ugur Gürlevik | Mustafa Değer Bilgeç | Muzaffer Güneş

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Göz Hastalıkları

Dergi:

Osmangazi Tıp Dergisi Vol.46 Issue 3, pp.422-428

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001313504

pISSN:

1305-4953

Age-related Macular Degeneration

Parkinson

prevalence

stage

typeYaşa Bağlı Makula Dejenerasyonu

Parkinson hastalığı

prevalans

evre

tip

Sayı

Makale detayları

Yazarlar: Erdoğan Yaşar | Ugur Gürlevik | Mustafa Değer Bilgeç | Muzaffer Güneş

Yayıncı: Eskişehir Osmangazi University

Ana Başlıklar: Göz Hastalıkları

Dergi: Osmangazi Tıp Dergisi Vol.46 Issue 3, pp.422-428

Belge Tipi: Makale

Yayın Tarihi: 5/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001313504

pISSN: 1305-4953

Sayı

Yazarlar:

Erdoğan Yaşar | Ugur Gürlevik | Mustafa Değer Bilgeç | Muzaffer Güneş

Yayıncı:

Eskişehir Osmangazi University

Ana Başlıklar:

Göz Hastalıkları

Dergi:

Osmangazi Tıp Dergisi Vol.46 Issue 3, pp.422-428

Belge Tipi:

Makale

Yayın Tarihi:

5/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001313504

pISSN:

1305-4953