Effects of Dietary Salt on Blood Pressure, Heart Rate, Extracellular Fluid Volume and Glomerular Filtration Rate in Diabetic Rats

Besim ÖZAYKAN

Makale detayları

Effects of Dietary Salt on Blood Pressure, Heart Rate, Extracellular Fluid Volume and Glomerular Filtration Rate in Diabetic Rats

Yazarlar:

Besim ÖZAYKAN

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 3, pp.219-226

Belge Tipi:

Makale

Yayın Tarihi:

2/1999

Belge Dili:

İngilizce

Document ID (Org No.):

2000757970

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

In the present study, we aimed to  investigate the effects of dietary salt  restriction and loading on extracellular fluid  volume (ECFV), blood pressure (BP), heart  rate (HR), glomerular filtration rate (GFR)  and renal hypertrophy in diabetic rats.  Diabetes was induced by injection of  streptozotocin (STZ, 65 mg/kg, iv) into male  Wistar rats. Four groups were formed: a) the  diabetic rats given a standard rat diet (DC),  b) the diabetic rats given a high-salt diet  (DHS), c) the diabetic rats given a low-salt  diet (DLS), d) the nondiabetic rats given a  standard rat diet (C). Salt loading and salt  restriction were started 7 days after STZ  injection and continued for a one-week.  Diabetes did not affect ECFV and GFR values  significantly, but it led to renal hypertrophy, a  reduction in blood pressure (p.

 

In the present study, we aimed to  investigate the effects of dietary salt  restriction and loading on extracellular fluid  volume (ECFV), blood pressure (BP), heart  rate (HR), glomerular filtration rate (GFR)  and renal hypertrophy in diabetic rats.  Diabetes was induced by injection of  streptozotocin (STZ, 65 mg/kg, iv) into male  Wistar rats. Four groups were formed: a) the  diabetic rats given a standard rat diet (DC),  b) the diabetic rats given a high-salt diet  (DHS), c) the diabetic rats given a low-salt  diet (DLS), d) the nondiabetic rats given a  standard rat diet (C). Salt loading and salt  restriction were started 7 days after STZ  injection and continued for a one-week.  Diabetes did not affect ECFV and GFR values  significantly, but it led to renal hypertrophy, a  reduction in blood pressure (p.

Makale detayları

Effects of Dietary Salt on Blood Pressure, Heart Rate, Extracellular Fluid Volume and Glomerular Filtration Rate in Diabetic Rats

Yazarlar:

Besim ÖZAYKAN

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 3, pp.219-226

Belge Tipi:

Makale

Yayın Tarihi:

2/1999

Belge Dili:

İngilizce

Document ID (Org No.):

2000757970

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Diabetes

blood pressure

extracellular fluid volume

glomerular filtration rate

dietary salt.

Sayı

Makale detayları

Effects of Dietary Salt on Blood Pressure, Heart Rate, Extracellular Fluid Volume and Glomerular Filtration Rate in Diabetic Rats

Yazarlar: Besim ÖZAYKAN

Yayıncı: TUBITAK

Ana Başlıklar: Sağlık teşvikleri

Dergi: Turkish Journal of Medical Sciences 1999 Vol.29 Issue 3, pp.219-226

Belge Tipi: Makale

Yayın Tarihi: 2/1999

Belge Dili: İngilizce

Document ID (Org No.): 2000757970

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Diabetes

blood pressure

extracellular fluid volume

glomerular filtration rate

dietary salt.

Sayı

Yazarlar:

Besim ÖZAYKAN

Yayıncı:

TUBITAK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 3, pp.219-226

Belge Tipi:

Makale

Yayın Tarihi:

2/1999

Belge Dili:

İngilizce

Document ID (Org No.):

2000757970

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144