Successful treatment with intravenous lipid emulsion of severe tricyclic antidepressant intoxication

Hızır AKDEMİR; Yavuz CENİK; Mustafa URAS; Neslihan ÜNAL

Makale detayları

Successful treatment with intravenous lipid emulsion of severe tricyclic antidepressant intoxication

Yazarlar:

Hızır AKDEMİR | Yavuz CENİK | Mustafa URAS | Neslihan ÜNAL

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 1, pp.43-46

Belge Tipi:

Makale

Yayın Tarihi:

1/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507724

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483

Özet:

 

An overdose of amitriptyline has neurological and cardiovascular side effects (psychosis, lethargy, coma, hypotension, and dysrhythmia). A 19-year-old female patient was admitted to our emergency service after a suicide attempt by amitriptyline ingestion of unknown amount. Her follow-up demonstrated deteriorating consciousness and vital signs, she had a generalized tonic-clonic seizure, and her electrocardiogram (ECG) revealed QRS interval widening followed by a ventricular tachycardia (VT) attack. The patient was treated with intravenous (IV) diazepam (Diazem®) to control the epileptic seizure, IV lidocaine (Aritmal®) to stop the VT attack, and IV sodium bicarbonate due to QRS interval widening. The patient was given norepinephrine bitartrate (Steradine®) and dopamine hydrochloride (Dopamine®) due to low blood pressure. Intravenous lipid emulsion (ILE) therapy was started due to the uncontrolled rhythm and hypotension. Here, we present a case report of a comatose patient with dysrhythmia due to amitriptyline overdose who responds to ILE therapy.

Makale detayları

Successful treatment with intravenous lipid emulsion of severe tricyclic antidepressant intoxication

Yazarlar: Hızır AKDEMİR | Yavuz CENİK | Mustafa URAS | Neslihan ÜNAL

Yayıncı: Ondokuz Mayıs University

Ana Başlıklar: Sağlık teşvikleri

Dergi: Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 1, pp.43-46

Belge Tipi: Makale

Yayın Tarihi: 1/2021

Belge Dili: İngilizce

Document ID (Org No.): 2000507724

Sıklık: Üç Aylık

eISSN: 1309-5129

pISSN: 1309-4483

Sayı

Yazarlar:

Hızır AKDEMİR | Yavuz CENİK | Mustafa URAS | Neslihan ÜNAL

Yayıncı:

Ondokuz Mayıs University

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Journal of Experimental and Clinical Medicine 2021 Vol.38 Issue 1, pp.43-46

Belge Tipi:

Makale

Yayın Tarihi:

1/2021

Belge Dili:

İngilizce

Document ID (Org No.):

2000507724

Sıklık:

Üç Aylık

eISSN:

1309-5129

pISSN:

1309-4483