SON DÖNEM KRONİK BÖBREK YETMEZLİĞİNDE PARATİROİD BEZLERİNİN ULTRASONOGROFİK BOYUTLARININ KALSİYUM METABOLİZMASI VE KEMİK DÖNGÜSÜ İLE İLİŞKİSİ VE ERİTROPOETİN TEDAVİSİNİN ROLÜ

Harun DÜĞEROĞLU; Ümit ÖZTÜRK; Mustafa ÖZTÜRK

Makale detayları

SON DÖNEM KRONİK BÖBREK YETMEZLİĞİNDE PARATİROİD BEZLERİNİN ULTRASONOGROFİK BOYUTLARININ KALSİYUM METABOLİZMASI VE KEMİK DÖNGÜSÜ İLE İLİŞKİSİ VE ERİTROPOETİN TEDAVİSİNİN ROLÜ

Yazarlar:

Harun DÜĞEROĞLU | Ümit ÖZTÜRK | Mustafa ÖZTÜRK

Yayıncı:

Afyonkarahisar Sağlık Bilimleri Üniversitesi

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Kocatepe Medical Journal 2019 Vol.20 Issue 1, pp.19-25

Belge Tipi:

Makale

Yayın Tarihi:

2/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000532479

Sıklık:

Aylık

eISSN:

2149-7869

Özet:

 


OBJECTIVE: The aim of the study is to determine the association of parathyroid gland dimensions with hyperparathyroidism and bone disease in patients with end stage chronic renal failure and to demonstrate its association with erythropoietin treatment. MATERIAL AND METHODS: Twenty patients undergoing renal replacement therapy at the continuous ambulatory peritoneal dialysis (CAPD) unit, 40 patients from hemodialysis unit and 40 patients with stage 4 predialysis (GRF 15-29 ml / min) were included in the study. Patient parathyroid ultrasonography, biochemistry-hematology tests and bone mineral densitometry (BMD) measurements were performed. RESULTS: The PTH values of predialysis patients were lower than those of SAPD and hemodialysis patients (respectively p=0.002, p=0.001). Patients with predialysis had a lower number of adenomas than patients with peritoneal dialysis (p=0.015). The parathyroid adenoma volume of patients with predialysis was lower than that of hemodialysis patients (p=0.032). The total erythropoetin (EPO) dose used in the last year; showed positive correlation with PTH level, adenoma number, adenome volume, and bone building markers (osteocalcin and alkaline phosphatase) (respectively r=0.257 p=0.021, r=0.312 p=0.005). Mean PTH values were 496.5 ± 439.7 pg / ml and there was a positive correlation between adenoma volume and PTH secretion (p=0.001).

CONCLUSIONS: Patients with the highest autonomic levels of PTH secretion were the patients with the most erythropoetin use. These findings suggest that erythropoetin not only increases parathyroid gland size but also increases autonomy

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Makale detayları

SON DÖNEM KRONİK BÖBREK YETMEZLİĞİNDE PARATİROİD BEZLERİNİN ULTRASONOGROFİK BOYUTLARININ KALSİYUM METABOLİZMASI VE KEMİK DÖNGÜSÜ İLE İLİŞKİSİ VE ERİTROPOETİN TEDAVİSİNİN ROLÜ

Yazarlar: Harun DÜĞEROĞLU | Ümit ÖZTÜRK | Mustafa ÖZTÜRK

Yayıncı: Afyonkarahisar Sağlık Bilimleri Üniversitesi

Ana Başlıklar: Sağlık teşvikleri

Dergi: Kocatepe Medical Journal 2019 Vol.20 Issue 1, pp.19-25

Belge Tipi: Makale

Yayın Tarihi: 2/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000532479

Sıklık: Aylık

eISSN: 2149-7869

Sayı

Yazarlar:

Harun DÜĞEROĞLU | Ümit ÖZTÜRK | Mustafa ÖZTÜRK

Yayıncı:

Afyonkarahisar Sağlık Bilimleri Üniversitesi

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Kocatepe Medical Journal 2019 Vol.20 Issue 1, pp.19-25

Belge Tipi:

Makale

Yayın Tarihi:

2/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000532479

Sıklık:

Aylık

eISSN:

2149-7869