The Relationship Between Mean Platelet Volume/Platelet Count (MPV/ PLT) Ratio and Peripheral Artery Disease

Serhat Çalışkan; Ferit Böyük

Makale detayları

The Relationship Between Mean Platelet Volume/Platelet Count (MPV/ PLT) Ratio and Peripheral Artery Disease

Yazarlar:

Serhat Çalışkan | Ferit Böyük

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Genel Tıp Dergisi Vol.33 Issue 1, pp.76-81

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284534

pISSN:

2602-3741

Anahtar kelimeler:

Özet:

 BackgroundAim: In our study, we aimed to evaluate the effect of mean platelet volumeplatelet count ratio on the development of peripheral artery disease PAD by comparing it with the control group. Material and Methods: A total of 115 patients with peripheral artery disease as a result of lower extremity color Doppler ultrasonography examination in our hospital were included in the study as the patient group and 100 individuals without peripheral artery disease as the control group. Results: History of coronary artery disease p0.001, diabetes mellitus p0.009, hypertension p0.001 and smoking history p0.001 were significantly higher in the PAD group than in the control group. Serum glucose 121.2725.66 vs. 104.8134.77; p0.001, MPV levels 9.990.79 vs. 9.040.7; p0.001 and MPVPLT ratio 0.0410.07 vs. 0.0370.006, p 0.001 were found to be significantly higher in the PAD group than in the control group. Serum HDL levels 45.0311.5 vs. 48.6712.52 p0.026 were significantly lower in the PAD group than in the control group. In multivariate analysis, age, MPV and MPVPLT ratio were determined as independent predictors for peripheral arterial disease. Conclusion: In our study, we found that MPV and MPVPLT ratio were independent predictors of peripheral artery disease.

 BackgroundAim: In our study, we aimed to evaluate the effect of mean platelet volumeplatelet count ratio on the development of peripheral artery disease PAD by comparing it with the control group. Material and Methods: A total of 115 patients with peripheral artery disease as a result of lower extremity color Doppler ultrasonography examination in our hospital were included in the study as the patient group and 100 individuals without peripheral artery disease as the control group. Results: History of coronary artery disease p0.001, diabetes mellitus p0.009, hypertension p0.001 and smoking history p0.001 were significantly higher in the PAD group than in the control group. Serum glucose 121.2725.66 vs. 104.8134.77; p0.001, MPV levels 9.990.79 vs. 9.040.7; p0.001 and MPVPLT ratio 0.0410.07 vs. 0.0370.006, p 0.001 were found to be significantly higher in the PAD group than in the control group. Serum HDL levels 45.0311.5 vs. 48.6712.52 p0.026 were significantly lower in the PAD group than in the control group. In multivariate analysis, age, MPV and MPVPLT ratio were determined as independent predictors for peripheral arterial disease. Conclusion: In our study, we found that MPV and MPVPLT ratio were independent predictors of peripheral artery disease.

 BackgroundAim: In our study, we aimed to evaluate the effect of mean platelet volumeplatelet count ratio on the development of peripheral artery disease PAD by comparing it with the control group. Material and Methods: A total of 115 patients with peripheral artery disease as a result of lower extremity color Doppler ultrasonography examination in our hospital were included in the study as the patient group and 100 individuals without peripheral artery disease as the control group. Results: History of coronary artery disease p0.001, diabetes mellitus p0.009, hypertension p0.001 and smoking history p0.001 were significantly higher in the PAD group than in the control group. Serum glucose 121.2725.66 vs. 104.8134.77; p0.001, MPV levels 9.990.79 vs. 9.040.7; p0.001 and MPVPLT ratio 0.0410.07 vs. 0.0370.006, p 0.001 were found to be significantly higher in the PAD group than in the control group. Serum HDL levels 45.0311.5 vs. 48.6712.52 p0.026 were significantly lower in the PAD group than in the control group. In multivariate analysis, age, MPV and MPVPLT ratio were determined as independent predictors for peripheral arterial disease. Conclusion: In our study, we found that MPV and MPVPLT ratio were independent predictors of peripheral artery disease.

 Amaç: Çalışmamızda ortalama trombosit hacmitrombosit sayısı oranının periferik arter hastalığı PAH gelişimine etkisini kontrol grubu ile karşılaştırarak değerlendirmeyi amaçladık. Yöntem: Hastanemizde alt ekstremite renkli Doppler ultrasonografi incelemesi sonucu periferik arter hastalığı saptanan toplam 115 hasta ile periferik arter hastalığı olmayan 100 kişi kontrol olarak çalışmaya alınmıştır. Bulgular: Periferik arter hastalığı PAD olan grupta ortalama yaş kontrol grubuna göre anlamlı olarak yüksek bulunmuştur 69.1210.58 vs. 52.8313.05, p0.001. Grupların cinsiyet oranlarında istatistiksel olarak anlamlı fark yoktur p0.218. Koroner arter hastalığı öyküsü p0.001, diabetes mellitus p0.009, hipertansiyon p0.001 ve sigara öyküsü p0.001 PAH grubunda kontrol grubuna göre anlamlı olarak yüksek bulunmuştur. Serum glukozu 121,2725,66 - 104,8134,77; p0,001, MPV seviyeleri 9,990,79 - 9,040,7; p0,001 ve MPVPLT oranı 0,0410,07 - 0,0370,006, p 0.001 PAD grubunda kontrol grubuna göre anlamlı olarak yüksek bulunmuştur. Serum HDL düzeyleri 45,0311,5e karşı 48,6712,52 p0,026 PAD grubunda kontrol grubuna göre anlamlı olarak düşüktür. Çok değişkenli analizde yaş, MPV ve MPVPLT oranı periferik arter hastalığı için bağımsız belirteçler olarak belirlenmiştir. Sonuç: Çalışmamızda MPV ve MPVPLT yapıları periferik arter yapısından bağımsız aygıtları bulunmuştur.

Makale detayları

The Relationship Between Mean Platelet Volume/Platelet Count (MPV/ PLT) Ratio and Peripheral Artery Disease

Yazarlar:

Serhat Çalışkan | Ferit Böyük

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Genel Tıp Dergisi Vol.33 Issue 1, pp.76-81

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284534

pISSN:

2602-3741

Peripheral arterial disease

Platelet activation

Mean Platelet Volume

Mean Platelet Volume/Platelet Count Ratio

Periferik arter hastalığı

Trombosit aktivasyonu

Ortalama Trombosit Hacmi

Ortalama Trombosit Hacmi/Platelet Sayısı Oranı

Periferik arter hastalığı

Trombosit aktivasyonu

Ortalama Trombosit Hacmi

Ortalama Trombosit Hacmi/Platelet Sayısı Oranı

Sayı

Makale detayları

Yazarlar: Serhat Çalışkan | Ferit Böyük

Yayıncı: Selcuk University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Genel Tıp Dergisi Vol.33 Issue 1, pp.76-81

Belge Tipi: Makale

Yayın Tarihi: 2/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001284534

pISSN: 2602-3741

Sayı

Yazarlar:

Serhat Çalışkan | Ferit Böyük

Yayıncı:

Selcuk University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Genel Tıp Dergisi Vol.33 Issue 1, pp.76-81

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001284534

pISSN:

2602-3741