Synthesis of some o-Hidroksi Enaminone Derivatives and Cyclohexadiene by Tandem Oxidative-Reaction in Tetrachloro-1,4-benzoquinone (TCB) Medium

Nesimi Uludağ

Makale detayları

Synthesis of some o-Hidroksi Enaminone Derivatives and Cyclohexadiene by Tandem Oxidative-Reaction in Tetrachloro-1,4-benzoquinone (TCB) Medium

Yazarlar:

Nesimi Uludağ

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 4, pp.2168-2175

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001301614

pISSN:

2148-2446

Anahtar kelimeler:

Özet:

 In this study, 7 original o-hydroxy aryl enaminone and cyclohexadiene derivatives were synthesized by tandem reaction in TCB medium and their structures were elucidated by 1H NMR, 13C NMR and HR-MS spectroscopy. Also, this reaction includes oxidative coupling and intramolecular cyclization reaction. Chromones are a group of naturally occurring compounds. It is ubiquitous in nature, especially in plants. Since cyclic chromones have common natural biologically active properties, it is thought that the synthesis of each chromone derivative that enters the literature will make an important contribution to the literature. The percent yields of the synthesized compounds were quite high and occurred under mild conditions at room temperature.

 In this study, 7 original o-hydroxy aryl enaminone and cyclohexadiene derivatives were synthesized by tandem reaction in TCB medium and their structures were elucidated by 1H NMR, 13C NMR and HR-MS spectroscopy. Also, this reaction includes oxidative coupling and intramolecular cyclization reaction. Chromones are a group of naturally occurring compounds. It is ubiquitous in nature, especially in plants. Since cyclic chromones have common natural biologically active properties, it is thought that the synthesis of each chromone derivative that enters the literature will make an important contribution to the literature. The percent yields of the synthesized compounds were quite high and occurred under mild conditions at room temperature.

 In this study, 7 original o-hydroxy aryl enaminone and cyclohexadiene derivatives were synthesized by tandem reaction in TCB medium and their structures were elucidated by 1H NMR, 13C NMR and HR-MS spectroscopy. Also, this reaction includes oxidative coupling and intramolecular cyclization reaction. Chromones are a group of naturally occurring compounds. It is ubiquitous in nature, especially in plants. Since cyclic chromones have common natural biologically active properties, it is thought that the synthesis of each chromone derivative that enters the literature will make an important contribution to the literature. The percent yields of the synthesized compounds were quite high and occurred under mild conditions at room temperature.

 Bu çalışmada 7 adet orjinal o-hidroksi aril enaminon ile siklohekzadienin türevleri TCB ortamında tandem reaksiyonu ile sentezlenip, yapıları 1H NMR, 13C NMR ve HR-MS spektroskopisi aydınlatılmıştır. Ayrıca, bu reaksiyon oxidatif birleşme ve molekül içi halkalaşma tepkimesini içermektedir. Kromonlar, doğal olarak oluşan bileşiklerden meydana gelen bir gruptur. Doğada, özellikle bitkilerin bileşenleri içerisinde bulunur. Halkalı kromonların yaygın olarak doğal biyolojik aktif özelliklere sahip olmasından dolayı, literatüre giren her kromon türevlerinin sentezi literatüre önemli katkı yapacağı düşünülmektedir. Bu çalışmada sentezlenen söz konusu bileşiklerin yüzdesel verimleri oldukça yüksek değerlere sahip olup, oda sıcaklığında ılımlı şartlarda gerçekleştirilmiştir.

Makale detayları

Synthesis of some o-Hidroksi Enaminone Derivatives and Cyclohexadiene by Tandem Oxidative-Reaction in Tetrachloro-1,4-benzoquinone (TCB) Medium

Yazarlar:

Nesimi Uludağ

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 4, pp.2168-2175

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001301614

pISSN:

2148-2446

TCB

Oxidation

Tandem annulationTCB

Oksidasyon

Tandem halkalaşması

Sayı

Makale detayları

Synthesis of some o-Hidroksi Enaminone Derivatives and Cyclohexadiene by Tandem Oxidative-Reaction in Tetrachloro-1,4-benzoquinone (TCB) Medium

Yazarlar: Nesimi Uludağ

Yayıncı: Duzce University

Ana Başlıklar: Mühendislik

Dergi: Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 4, pp.2168-2175

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: Türkçe

Document ID (Org No.): 2001301614

pISSN: 2148-2446

TCB

Oxidation

Tandem annulationTCB

Oksidasyon

Tandem halkalaşması

Sayı

Yazarlar:

Nesimi Uludağ

Yayıncı:

Duzce University

Ana Başlıklar:

Mühendislik

Dergi:

Düzce Üniversitesi Bilim ve Teknoloji Dergisi Vol.11 Issue 4, pp.2168-2175

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

Türkçe

Document ID (Org No.):

2001301614

pISSN:

2148-2446