Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects

Sevilay ZORA; Turkan YİGİTBASİ; Gozde ULFER; Nesrin EMEKLİ

Makale detayları

Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects

Yazarlar:

Sevilay ZORA | Turkan YİGİTBASİ | Gozde ULFER | Nesrin EMEKLİ

Yayıncı:

Istanbul University

Dergi:

European Journal of Biology 2018 Vol.77 Issue 2, pp.55-58

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000424456

eISSN:

2618-6144

pISSN:

2602-2575

Özet:

 


DOI: 10.26650/EurJBiol.2018.18008


Objective: Ghrelin is a hormone with
peptide structure. It has fatty tissue and increases appetite. Obesity is a
multifactorial chronic disease characterized by an increase in fat tissue. Fat
tissue, like the endocrine organ, triggers oxidative stress and can lead to the
development of obesity-related pathologies. The purpose of this study is to
examine the relationship between the ghrelin in blood, and oxidative stress and
lipid parameters. 

Materials and Methods: The study was
conducted with  61 obese and 24 healthy
individuals. Ghreline levels were measured using the ELISA method, while total
antioxidant status (TAS) and oxidant status (TOS), triglyceride (TG), total
cholesterol (TC), HDL-cholesterol (HDL-C) and LDL cholesterol (LDL-C) levels
were measured using the photometric method.

Results: A negative correlation was found
between body mass index (BMI) and ghrelin levels in the obese group
(p0.05). TAS was observed to be lower in obese compared
to control group, while The Oxidative Stress Index (OSI) was found to be
significantly higher than the obese group (p0.05). 

Conclusion: Increasing obesity level (BMI)
and decreasing ghrelin level were found to be correlated. New studies are
needed in order to discover the changes in ghrelin level connected to oxidative
stress. 

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Makale detayları

Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects

Yazarlar: Sevilay ZORA | Turkan YİGİTBASİ | Gozde ULFER | Nesrin EMEKLİ

Yayıncı: Istanbul University

Dergi: European Journal of Biology 2018 Vol.77 Issue 2, pp.55-58

Belge Tipi: Makale

Yayın Tarihi: 12/2018

Belge Dili: İngilizce

Document ID (Org No.): 2000424456

eISSN: 2618-6144

pISSN: 2602-2575

Sayı

Yazarlar:

Sevilay ZORA | Turkan YİGİTBASİ | Gozde ULFER | Nesrin EMEKLİ

Yayıncı:

Istanbul University

Dergi:

European Journal of Biology 2018 Vol.77 Issue 2, pp.55-58

Belge Tipi:

Makale

Yayın Tarihi:

12/2018

Belge Dili:

İngilizce

Document ID (Org No.):

2000424456

eISSN:

2618-6144

pISSN:

2602-2575