Phytochemical Characterization of Achillea grandifolia Friv. Essential Oil and Its Potent Against Oxidative Damage, Acetylcholinesterase and a-Amylase

Gulmira OZEK

Makale detayları

Phytochemical Characterization of Achillea grandifolia Friv. Essential Oil and Its Potent Against Oxidative Damage, Acetylcholinesterase and a-Amylase

Yazarlar:

Gulmira OZEK

Yayıncı:

Eskisehir Technical University

Dergi:

Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 2018 Vol.19 Issue 3, pp.671-684

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

Türkçe

Document ID (Org No.):

2000417045

pISSN:

2667-4211

Özet:

 

The essential oil of Achillea grandifolia Friv. was obtained by hydrodistillation of aerial parts of the plant and analyzed with GC-FID and GC/MS techniques. The oil comprised mostly by the oxygenated monoterpenes (76.2 %) with a-terpinyl acetate (54.1 %) as main constituent. The monoterpene hydrocarbons were the second major compound group with p-cymene (17.7 %) as the main representative. The essential oil showed free radical scavenging activity against DPPH• radicals (Inh. 52 %) and ABTS+• cation radicals (TEAC 0.62 mM). The oil demonstrated hypoglycemic activity via inhibition of a-amylase (IC50 0.15 mg/mL). The effect of the oil on neurodegenerative disease was expressed via inhibition of AChE and found to be > 82 % of inhibition (an IC50 of 1.77 mg/mL).

Makale detayları

Phytochemical Characterization of Achillea grandifolia Friv. Essential Oil and Its Potent Against Oxidative Damage, Acetylcholinesterase and a-Amylase

Yazarlar: Gulmira OZEK

Yayıncı: Eskisehir Technical University

Dergi: Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 2018 Vol.19 Issue 3, pp.671-684

Belge Tipi: Makale

Yayın Tarihi: 8/2018

Belge Dili: Türkçe

Document ID (Org No.): 2000417045

pISSN: 2667-4211

Sayı

Yazarlar:

Gulmira OZEK

Yayıncı:

Eskisehir Technical University

Dergi:

Eskişehir Technical University Journal of Science and Technology A - Applied Sciences and Engineering 2018 Vol.19 Issue 3, pp.671-684

Belge Tipi:

Makale

Yayın Tarihi:

8/2018

Belge Dili:

Türkçe

Document ID (Org No.):

2000417045

pISSN:

2667-4211