Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia

Hasan Hüseyin Kır; Betigül Yürüten Çorbacıoğlu; Osman Serhat Tokgöz

Makale detayları

Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia

Yazarlar:

Hasan Hüseyin Kır | Betigül Yürüten Çorbacıoğlu | Osman Serhat Tokgöz

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.463-471

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286357

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent periodSP method which is an inhibitor reflex. Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid SCM muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups. Results: The mean age of the patients participating in the study was 49.3  14.7, and the control group was 48.0  13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared. Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This disorganization may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.

 Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent periodSP method which is an inhibitor reflex. Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid SCM muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups. Results: The mean age of the patients participating in the study was 49.3  14.7, and the control group was 48.0  13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared. Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This disorganization may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.

 Purpose: The aim of this study to examine the in changes inhibitory interneurons of the brainstem, which are likely to be involved in pathophysiology of cervical dystonia, using the cutaneous silent periodSP method which is an inhibitor reflex. Materials and Methods: SP latency and interval values were obtained from bilateral sternocleidomastoid SCM muscles of individuals in 20 patients with cervical dystonia and 25 healthy volunteers using superficial electrodes. SP parameters obtained were compared within and between groups. Furthermore, intra-individual correlation analysis was performed for SP parameters from bilateral SCMs of the individuals in both groups. Results: The mean age of the patients participating in the study was 49.3  14.7, and the control group was 48.0  13.7. There was no statistically significant difference between the two groups in terms of age and gender. No significant difference was found in the comparison of SP parameters both within and between groups. There was a strong intra-individual correlation between SP latencies of bilateral SCMs of both patient and control groups. It was determined that the strongly positive intra-individual correlation between SP intervals also continued in the control group, whereas at patient group disappeared. Conclusion: The loss of correlation between bilateral SCM SP durations in the dystonia group indicates that the abnormality in interneuron connections, which is thought to be present in dystonia, may actually be a loss of order. This disorganization may explain the discrepancies in the results of cutaneous SP studies in dystonia patients.

 Amaç: Bu çalışmada servikal distoni patofizyolojisinde rol oynaması muhtemel beyin sapı inhibitör internöronlarındaki değişikliklerin inhibitör bir refleks olan kutanöz sessiz periyotSP yöntemi ile incelenmesi amaçlandı. Gereç ve Yöntem: Servikal distonisi olan 20 hasta ve 25 sağlıklı gönüllünün bilateral sternokleidomastoid SCM kaslarından yüzeyel elektrotlar kullanılarak SP latans ve interval değerleri elde edildi. Elde edilen SP parametreleri gruplar içinde ve gruplar arasında karşılaştırıldı. Ayrıca her iki grupta karşılıklı SCMlerinin SP parametrelerinin grup içi korelasyon analizi yapılmıştır. Bulgular: Çalışmaya katılan hastaların yaş ortalaması 49,3  14,7, kontrol grubunun 48,0  13,7 olup iki grup arasında yaş ve cinsiyet açısından istatistiksel olarak anlamlı bir fark saptanmadı. Grup içi ve gruplar arası SP parametreleri arasında anlamlı fark saptanmadı. Hem hasta hem de kontrol gruplarında bilateral SCMlerin SP latansları arasında güçlü bir birey içi korelasyon vardı. Birey içi SP intervalleri arasındaki güçlü pozitif korelasyonun kontrol grubunda da devam ettiği, hasta grupta ise kaybolduğu gözlendi. Sonuç: Distoni hastalarında yapılmış olan kutanöz SP çalışmalarının sonuçları oldukça farklıdır. Distoni grubunda bilateral SCM SP süreleri arasındaki korelasyon kaybı, distonide var olduğu düşünülen aranöronlar arası bağlantılardaki anormalliğin aslında bir düzen kaybı olabileceğini göstermektedir. Bu düzensizlik, distoni hastalarında kutanöz SP çalışmalarının sonuçlarındaki tutarsızlıkları açıklayabilir.

Makale detayları

Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia

Yazarlar:

Hasan Hüseyin Kır | Betigül Yürüten Çorbacıoğlu | Osman Serhat Tokgöz

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.463-471

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286357

pISSN:

2602-3032

Cervical Dystonia

Interneurons

Electromyography

Servikal Distoni

Aranöronlar

Elektromiyografi

Sayı

Makale detayları

Evaluation of sternocleidomastoid muscle cutaneous silent period in patients with cervical dystonia

Yazarlar: Hasan Hüseyin Kır | Betigül Yürüten Çorbacıoğlu | Osman Serhat Tokgöz

Yayıncı: Cukurova University

Ana Başlıklar: Klinik Tıp Bilimleri

Dergi: Cukurova Medical Journal Vol.48 Issue 2, pp.463-471

Belge Tipi: Makale

Yayın Tarihi: 2/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001286357

pISSN: 2602-3032

Cervical Dystonia

Interneurons

Electromyography

Servikal Distoni

Aranöronlar

Elektromiyografi

Sayı

Yazarlar:

Hasan Hüseyin Kır | Betigül Yürüten Çorbacıoğlu | Osman Serhat Tokgöz

Yayıncı:

Cukurova University

Ana Başlıklar:

Klinik Tıp Bilimleri

Dergi:

Cukurova Medical Journal Vol.48 Issue 2, pp.463-471

Belge Tipi:

Makale

Yayın Tarihi:

2/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001286357

pISSN:

2602-3032