An evaluation of risk factors for overall complications  after curative gastrectomy in gastric cancer patients aged 65 or over

Serdar Şenol; Mustafa Kuşak; Ahmet Can Sarı; Mehmet Emin Kara

Makale detayları

An evaluation of risk factors for overall complications after curative gastrectomy in gastric cancer patients aged 65 or over

Yazarlar:

Serdar Şenol | Mustafa Kuşak | Ahmet Can Sarı | Mehmet Emin Kara

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji Cerrahisi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.596-600

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302576

pISSN:

2717-7505

Anahtar kelimeler:

Özet:

 Aim: The purpose of this study was to identify risk factors for postoperative complications in patients with gastric cancer aged 65 or over. Methods: Data from medical records in our database were reviewed and analyzed retrospectively. Two hundred twenty-nine patients with histologically confirmed gastric cancer underwent curative gastrectomy in our clinic between January 2017 and December 2021. Eighty-eight patients younger than 65 and 21 with previous histories of abdominal surgery, multi-visceral resection, emergency surgery due to perforation, bleeding, or obstruction, 18 with preoperative radiotherapy or chemotherapy were excluded. The remaining 102 patients, aged 65 years or over, were included in the study. Patient characteristics, intraoperative findings, and postoperative complications were evaluated. Results: Postoperative complications with ClavienDindo grade  II were observed in 29 patients 28.4. Univariate analysis showed that the prognostic nutritional index 45 odds ratio 0.91; 95 confidence interval, 0.86-0.97; p  0.004, controlling nutritional status score 5 odds ratio 1.27; 95 confidence interval, 1.09-1.49; p  0.002, and body mass index BMI 25 kgm2 odds ratio 1.97; 95 confidence interval, 1.00-1.26; p  0.042 significantly predicted postoperative complications. Multivariate analysis showed that BMI 25 kgm2 odds ratio 1.18; 95 confidence interval, 1.03-1.34; p  0.011 significantly predicted postoperative complications. Conclusion: The overall postoperative complication risk among older individuals with gastric cancer who underwent curative gastrectomy was significantly higher among high-BMI patients. Perioperative management with a focus on BMI is important in older patients undergoing elective curative gastrectomy.

 Aim: The purpose of this study was to identify risk factors for postoperative complications in patients with gastric cancer aged 65 or over. Methods: Data from medical records in our database were reviewed and analyzed retrospectively. Two hundred twenty-nine patients with histologically confirmed gastric cancer underwent curative gastrectomy in our clinic between January 2017 and December 2021. Eighty-eight patients younger than 65 and 21 with previous histories of abdominal surgery, multi-visceral resection, emergency surgery due to perforation, bleeding, or obstruction, 18 with preoperative radiotherapy or chemotherapy were excluded. The remaining 102 patients, aged 65 years or over, were included in the study. Patient characteristics, intraoperative findings, and postoperative complications were evaluated. Results: Postoperative complications with ClavienDindo grade  II were observed in 29 patients 28.4. Univariate analysis showed that the prognostic nutritional index 45 odds ratio 0.91; 95 confidence interval, 0.86-0.97; p  0.004, controlling nutritional status score 5 odds ratio 1.27; 95 confidence interval, 1.09-1.49; p  0.002, and body mass index BMI 25 kgm2 odds ratio 1.97; 95 confidence interval, 1.00-1.26; p  0.042 significantly predicted postoperative complications. Multivariate analysis showed that BMI 25 kgm2 odds ratio 1.18; 95 confidence interval, 1.03-1.34; p  0.011 significantly predicted postoperative complications. Conclusion: The overall postoperative complication risk among older individuals with gastric cancer who underwent curative gastrectomy was significantly higher among high-BMI patients. Perioperative management with a focus on BMI is important in older patients undergoing elective curative gastrectomy.

 Aim: The purpose of this study was to identify risk factors for postoperative complications in patients with gastric cancer aged 65 or over. Methods: Data from medical records in our database were reviewed and analyzed retrospectively. Two hundred twenty-nine patients with histologically confirmed gastric cancer underwent curative gastrectomy in our clinic between January 2017 and December 2021. Eighty-eight patients younger than 65 and 21 with previous histories of abdominal surgery, multi-visceral resection, emergency surgery due to perforation, bleeding, or obstruction, 18 with preoperative radiotherapy or chemotherapy were excluded. The remaining 102 patients, aged 65 years or over, were included in the study. Patient characteristics, intraoperative findings, and postoperative complications were evaluated. Results: Postoperative complications with ClavienDindo grade  II were observed in 29 patients 28.4. Univariate analysis showed that the prognostic nutritional index 45 odds ratio 0.91; 95 confidence interval, 0.86-0.97; p  0.004, controlling nutritional status score 5 odds ratio 1.27; 95 confidence interval, 1.09-1.49; p  0.002, and body mass index BMI 25 kgm2 odds ratio 1.97; 95 confidence interval, 1.00-1.26; p  0.042 significantly predicted postoperative complications. Multivariate analysis showed that BMI 25 kgm2 odds ratio 1.18; 95 confidence interval, 1.03-1.34; p  0.011 significantly predicted postoperative complications. Conclusion: The overall postoperative complication risk among older individuals with gastric cancer who underwent curative gastrectomy was significantly higher among high-BMI patients. Perioperative management with a focus on BMI is important in older patients undergoing elective curative gastrectomy.

 Amaç: Bu çalışmanın amacı, 65 yaş ve üstü mide kanserli hastalarda postoperatif komplikasyonlar için risk faktörlerini belirlemektir. Yöntem: Veri tabanımızdaki tıbbi kayıtlardan elde edilen veriler retrospektif olarak gözden geçirildi ve analiz edildi. Kliniğimizde Ocak 2017 ile Aralık 2021 tarihleri arasında mide kanseri tanısı almış, 229 hastaya küratif gastrektomi uygulandı. Altmış beş yaşından küçük olan seksen sekiz; karın cerrahisi, multivisseral rezeksiyon, perforasyon, kanama, tıkanıklık nedeniyle acil cerrahi öyküsü olan 21; preoperatif radyoterapi veya kemoterapi uygulanmış 18 hasta çalışmadan dışlandı. Altmış beş yaş ve üzeri 102 hasta çalışmaya dahil edildi. Hasta özellikleri, intraoperatif bulgular ve postoperatif komplikasyonlar değerlendirildi. Bulgular: Yirmi dokuz hastada 28.4 ClavienDindo derecesi  II olan postoperatif komplikasyonlar gözlendi. Tek değişkenli analizlerde, prognostik beslenme indeksinin 45 olasılık oranı 0,91; 95 güven aralığı, 0,86-0,97; p  0,004, kontrol beslenme durum skorunun 5 olasılık oranı 1,27; 95 güven aralığı, 1,09-1,49; p  0,002 ve vücut kitle indeksinin VKİ 25 kgm2 olasılık oranı 1,97; 95 güven aralığı, 1,00-1,26; p  0,042 postoperatif komplikasyonları anlamlı şekilde öngördüğü belirlendi. Çok değişkenli analizlerde, VKİnin 25 kgm2 olasılık oranı 1,18; 95 güven aralığı, 1,03-1,34; p  0,011 postoperatif komplikasyonları önemli ölçüde öngördüğü gösterildi. Sonuç: Küratif gastrektomi uygulanan 65 yaş ve üzeri mide kanserli bireylerde genel postoperatif komplikasyon riski, yüksek VKİli hastalarda anlamlı olarak daha yüksekti. Elektif küratif gastrektomi geçiren yaşlı hastalarda VKİye odaklanan perioperatif yönetim önemlidir.

Makale detayları

An evaluation of risk factors for overall complications after curative gastrectomy in gastric cancer patients aged 65 or over

Yazarlar:

Serdar Şenol | Mustafa Kuşak | Ahmet Can Sarı | Mehmet Emin Kara

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji Cerrahisi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.596-600

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302576

pISSN:

2717-7505

Gastric cancer

Older patients

Postoperative complication

Risk factorAmeliyat sonrası komplikasyon

Mide kanseri

Risk faktörü

Yaşlı hastalar

Sayı

Makale detayları

Yazarlar: Serdar Şenol | Mustafa Kuşak | Ahmet Can Sarı | Mehmet Emin Kara

Yayıncı: MediHealth Academy Yayıncılık

Ana Başlıklar: Gastroenteroloji Cerrahisi

Dergi: Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.596-600

Belge Tipi: Makale

Yayın Tarihi: 10/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001302576

pISSN: 2717-7505

Sayı

Yazarlar:

Serdar Şenol | Mustafa Kuşak | Ahmet Can Sarı | Mehmet Emin Kara

Yayıncı:

MediHealth Academy Yayıncılık

Ana Başlıklar:

Gastroenteroloji Cerrahisi

Dergi:

Journal of Medicine and Palliative Care Vol.4 Issue 5, pp.596-600

Belge Tipi:

Makale

Yayın Tarihi:

10/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001302576

pISSN:

2717-7505