The prevalence of subclinical hypothyroidism in obese children and adolescents and its effects on metabolic parameters

Nurullah ÇELİK

doi:https://doi.org/10.7197/cmj.vi.551051

Makale detayları

The prevalence of subclinical hypothyroidism in obese children and adolescents and its effects on metabolic parameters

Yazarlar:

Nurullah ÇELİK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2019 Vol.41 Issue 4, pp.691-697

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000922454

DOI:

https://doi.org/10.7197/cmj.vi.551051

Özet:

 


Objective: To compare cardiovascular risk factors in obese
patients with or without Subclinical
Hypothyroidism (SH),
also to estimate the prevalence of SH in obese children and adolescents.


Method: A total of 226 obese children and adolescents aged
6-18 years were included in the study. Two groups were created as euthyroid
group (n=195) and SH group (n=31). After an 8-12 hour overnight fasting, serum
blood glucose, insulin, HDL, LDL, cholesterol, triglyceride TSH, free T4, ALT,
AST levels were measured. HOMA-IR and atherogenic index (AI) were calculated.


Results: Prevalence of SH was estimated as 14.1 %. The values
of fasting glucose, fasting insülin, ALT, AST, TSH, HOMA-IR levels were
significantly higher ın SH group than euthyroid group. There was a positive
correlation between TSH and fasting glucose, insülin, triglyceride, ALT, AST,
HOMA-IR, AI. It was also demonstrated that the TSH level was significantly and
independently related to HOMA-IR value ın multiple regression analysis
(p=0.001).


Conclusions: Obese
patients with SH may be more susceptible to metabolic complications than
euthyroid subjects.


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Makale detayları

The prevalence of subclinical hypothyroidism in obese children and adolescents and its effects on metabolic parameters

Yazarlar: Nurullah ÇELİK

Ana Başlıklar: Sağlık teşvikleri

Dergi: Cumhuriyet Medical Journal 2019 Vol.41 Issue 4, pp.691-697

Belge Tipi: Makale

Yayın Tarihi: 12/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000922454

DOI: https://doi.org/10.7197/cmj.vi.551051

Sayı

Yazarlar:

Nurullah ÇELİK

Ana Başlıklar:

Sağlık teşvikleri

Dergi:

Cumhuriyet Medical Journal 2019 Vol.41 Issue 4, pp.691-697

Belge Tipi:

Makale

Yayın Tarihi:

12/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000922454

DOI:

https://doi.org/10.7197/cmj.vi.551051