Invasive orbital aspergillosis in an apparently immunocompetent host without evidence sinusitis

Jennifer Primeggia; George Cyriac; Princy Kumar

doi:https://doi.org/10.5799/ahinjs.02.2012.03.0054

Makale detayları

Invasive orbital aspergillosis in an apparently immunocompetent host without evidence sinusitis

Yazarlar:

Jennifer Primeggia | George Cyriac | Princy Kumar

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.113-116

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488014

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0054

Özet:

 

Jennifer Primeggia, George Cyriac, Princy Kumar 			  	     	Invasive aspergillosis is uncommon in healthy individuals. We report a case of Aspergillus fumigatus orbital cellulitis     	with intracranial extension in an apparently immunocompetent patient with a history of benign lymphoid hyperplasia     	of the lacrimal gland. A 68 year-old man with no signiicant past medical history underwent orbitotomy and biopsy of a     	lacrimal gland mass. Pathology showed benign lymphoid hyperplasia of the lacrimal gland and he completed radiation     	therapy. Three months after orbitotomy and one month after completion of radiation therapy, he presented with orbital     	cellulitis. Brain magnetic resonance imaging demonstrated invasion into the frontal lobe. Clinical and radiographic     	indings failed to improve with prolonged antibiotic therapy; transcranial orbitotomy with right frontal craniotomy for     	abscess drainage and orbit washout was performed. Intraoperative cultures grew Aspergillus fumigatus. The patient     	completed a six month course of therapy with oral voriconazole and has remained free from relapse with long-term     	follow-up. Eficacy of voriconazole was guided by serial imaging and voriconazole trough levels. Aspergillus may cause     	invasive disease in immunocompetent hosts, even without evidence of sinusitis, and should be considered in the dif-    	ferential diagnosis when patients do not demonstrate clinical improvement with antibiotic therapy.

Makale detayları

Invasive orbital aspergillosis in an apparently immunocompetent host without evidence sinusitis

Yazarlar: Jennifer Primeggia | George Cyriac | Princy Kumar

Yayıncı: Sağlık Araştırmaları Derneği

Dergi: Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.113-116

Belge Tipi: Makale

Yayın Tarihi: 8/2012

Belge Dili: İngilizce

Document ID (Org No.): 2000488014

Sıklık: Üç Aylık

eISSN: 2146-9369

pISSN: 2146-3158

DOI: https://doi.org/10.5799/ahinjs.02.2012.03.0054

Sayı

Yazarlar:

Jennifer Primeggia | George Cyriac | Princy Kumar

Yayıncı:

Sağlık Araştırmaları Derneği

Dergi:

Journal of Microbiology and Infectious Diseases 2012 Vol.2 Issue 03, pp.113-116

Belge Tipi:

Makale

Yayın Tarihi:

8/2012

Belge Dili:

İngilizce

Document ID (Org No.):

2000488014

Sıklık:

Üç Aylık

eISSN:

2146-9369

pISSN:

2146-3158

DOI:

https://doi.org/10.5799/ahinjs.02.2012.03.0054