Neutrophil-to-Lymphocyte Ratio as a Marker in Patients with Non-arteritic Anterior Ischemic Optic Neuropathy

Onur POLAT; Güliz Fatma YAVAŞ; Sibel İNAN; Ümit Übeyt İNAN

Makale detayları

Neutrophil-to-Lymphocyte Ratio as a Marker in Patients with Non-arteritic Anterior Ischemic Optic Neuropathy

Yazarlar:

Onur POLAT | Güliz Fatma YAVAŞ | Sibel İNAN | Ümit Übeyt İNAN

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2015 Vol.32 Issue 4, pp.382-387

Belge Tipi:

Makale

Yayın Tarihi:

9/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000759780

Sıklık:

İki Aylık

pISSN:

2146-3123

Özet:

 

Background: Non-arteritic anterior ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in patients over the age of 50 and is the second most common cause of permanent optic nerve-related visual loss in adults after glaucoma. Although the precise cause of NAION remains elusive, the etiology of NAION is believed to be multifactorial.     Aims: To evaluate the utility of neutrophil-to-lymphocyte ratio (NLR) as a simple and readily available prognostic factor for clinical disease activity in patients with NAION.     Study Design: Case-control study.     Methods: Forty-five patients with the diagnosis of NAION and 50 age- and sex-matched controls with/without any systemic or ocular diseases except cataract were retrospectively enrolled in the study. Demographic characteristics and laboratory findings including complete blood count of all patients and control subjects were obtained from the electronic medical record. The neutrophil and lymphocyte counts were recorded and the NLR was calculated.     Results: White blood cell, neutrophil, NLR and platelet values of the NAION patients were significantly higher than those of the controls (p<0.001, p<0.001, p=0.004, p=0.037, respectively). Initial NLR values were negatively correlated with initial and the third month best corrected visual acuity levels in the study group. The optimum NLR cut-off point for NAION was 1.94.     Conclusion: NLR could be considered as a new inflammatory marker for assessment of the severity of inflammation in NAION patients with its quick, cheap, easily measurable property with routine complete blood count analysis.

Makale detayları

Neutrophil-to-Lymphocyte Ratio as a Marker in Patients with Non-arteritic Anterior Ischemic Optic Neuropathy

Yazarlar: Onur POLAT | Güliz Fatma YAVAŞ | Sibel İNAN | Ümit Übeyt İNAN

Yayıncı: Trakya University

Dergi: Balkan Medical Journal 2015 Vol.32 Issue 4, pp.382-387

Belge Tipi: Makale

Yayın Tarihi: 9/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000759780

Sıklık: İki Aylık

pISSN: 2146-3123

Sayı

Yazarlar:

Onur POLAT | Güliz Fatma YAVAŞ | Sibel İNAN | Ümit Übeyt İNAN

Yayıncı:

Trakya University

Dergi:

Balkan Medical Journal 2015 Vol.32 Issue 4, pp.382-387

Belge Tipi:

Makale

Yayın Tarihi:

9/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000759780

Sıklık:

İki Aylık

pISSN:

2146-3123