Assessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Rats

Canan Çulha; Zeynep Ülkü Gün; Aysu Selçuk; Şule Apikoğlu-rabuş

Makale detayları

Assessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Rats

Yazarlar:

Canan Çulha | Zeynep Ülkü Gün | Aysu Selçuk | Şule Apikoğlu-rabuş

Yayıncı:

Marmara University

Ana Başlıklar:

Clinical Pharmacy and Pharmacy Practice

Dergi:

Clinical and Experimental Health Sciences Vol.13 Issue 3, pp.555-561

Belge Tipi:

Makale

Yayın Tarihi:

11/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001298177

pISSN:

2459-1459

Anahtar kelimeler:

Özet:

 Objective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil WGO and quince seed mucilage QSM in rats. Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO n6; topical QSM n6; and topical saline n6 as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization. Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization 11 days vs. 13 days. The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.

 Objective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil WGO and quince seed mucilage QSM in rats. Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO n6; topical QSM n6; and topical saline n6 as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization. Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization 11 days vs. 13 days. The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.

 Objective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil WGO and quince seed mucilage QSM in rats. Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO n6; topical QSM n6; and topical saline n6 as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization. Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization 11 days vs. 13 days. The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.

 Objective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil WGO and quince seed mucilage QSM in rats. Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO n6; topical QSM n6; and topical saline n6 as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization. Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization 11 days vs. 13 days. The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.

Makale detayları

Assessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Rats

Yazarlar: Canan Çulha | Zeynep Ülkü Gün | Aysu Selçuk | Şule Apikoğlu-rabuş

Yayıncı: Marmara University

Ana Başlıklar: Clinical Pharmacy and Pharmacy Practice

Dergi: Clinical and Experimental Health Sciences Vol.13 Issue 3, pp.555-561

Belge Tipi: Makale

Yayın Tarihi: 11/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001298177

pISSN: 2459-1459

Wound healing

wheat germ oil

quince seed mucilage

Sayı

Yazarlar:

Canan Çulha | Zeynep Ülkü Gün | Aysu Selçuk | Şule Apikoğlu-rabuş

Yayıncı:

Marmara University

Ana Başlıklar:

Clinical Pharmacy and Pharmacy Practice

Dergi:

Clinical and Experimental Health Sciences Vol.13 Issue 3, pp.555-561

Belge Tipi:

Makale

Yayın Tarihi:

11/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001298177

pISSN:

2459-1459