Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea

Zehra Aydın; Habip Almış; İbrahim Hakan Bucak; Mehmet Turğut

Makale detayları

Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea

Yazarlar:

Zehra Aydın | Habip Almış | İbrahim Hakan Bucak | Mehmet Turğut

Yayıncı:

Istanbul University

Ana Başlıklar:

Çocuk Sağlığı ve Hastalıkları

Dergi:

Çocuk Dergisi Vol.23 Issue 2, pp.113-118

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293958

pISSN:

1308-8491

Anahtar kelimeler:

Özet:

 Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to reach. This study aims to evaluate the parameters that help the diagnosis of rotavirus gastroenteritis. Material and Methods: We retrospectively reviewed 1,539 children aged 1 month to 18 years who had been admitted to our hospital for acute gastroenteritis. Patients were divided into two groups: rotavirus positive and rotavirus negative. There were 745 patients in the RV-positive group and 794 patients in the RV-negative group. Results: The mean RBC p0.005, Hb p0.001, Htc p0.001, MCV p0.001, neutrophil p0.001, PLR p0.003, NLR p0.001, and ELR p0.001 levels were significantly lower in the RV-positive group. The mean PLT level p0.005 and the mean lymphocyte level p0.001 were significantly higher in the RV-positive group. Conclusion: Several hematological parameters were influenced in rotavirus gastroenteritis. RBC, Hb, Htc, MCV, the mean platelet level, the mean neutrophil level, the mean lymphocyte level, platelet lymphocyte ratio, neutrophillymphocyte ratio, and the eosinophillymphocyte ratio could be supportive for rotavirus gastroenteritis.

 Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to reach. This study aims to evaluate the parameters that help the diagnosis of rotavirus gastroenteritis. Material and Methods: We retrospectively reviewed 1,539 children aged 1 month to 18 years who had been admitted to our hospital for acute gastroenteritis. Patients were divided into two groups: rotavirus positive and rotavirus negative. There were 745 patients in the RV-positive group and 794 patients in the RV-negative group. Results: The mean RBC p0.005, Hb p0.001, Htc p0.001, MCV p0.001, neutrophil p0.001, PLR p0.003, NLR p0.001, and ELR p0.001 levels were significantly lower in the RV-positive group. The mean PLT level p0.005 and the mean lymphocyte level p0.001 were significantly higher in the RV-positive group. Conclusion: Several hematological parameters were influenced in rotavirus gastroenteritis. RBC, Hb, Htc, MCV, the mean platelet level, the mean neutrophil level, the mean lymphocyte level, platelet lymphocyte ratio, neutrophillymphocyte ratio, and the eosinophillymphocyte ratio could be supportive for rotavirus gastroenteritis.

 Objective: Rotavirus is the most frequent cause of infectious acute gastroenteritis in children and may result in electrolyte imbalance, severe dehydration, hypovolemic shock, and death. Even though improved serological methods for definitive diagnosis exist, these methods may not always be easy to reach. This study aims to evaluate the parameters that help the diagnosis of rotavirus gastroenteritis. Material and Methods: We retrospectively reviewed 1,539 children aged 1 month to 18 years who had been admitted to our hospital for acute gastroenteritis. Patients were divided into two groups: rotavirus positive and rotavirus negative. There were 745 patients in the RV-positive group and 794 patients in the RV-negative group. Results: The mean RBC p0.005, Hb p0.001, Htc p0.001, MCV p0.001, neutrophil p0.001, PLR p0.003, NLR p0.001, and ELR p0.001 levels were significantly lower in the RV-positive group. The mean PLT level p0.005 and the mean lymphocyte level p0.001 were significantly higher in the RV-positive group. Conclusion: Several hematological parameters were influenced in rotavirus gastroenteritis. RBC, Hb, Htc, MCV, the mean platelet level, the mean neutrophil level, the mean lymphocyte level, platelet lymphocyte ratio, neutrophillymphocyte ratio, and the eosinophillymphocyte ratio could be supportive for rotavirus gastroenteritis.

 Amaç: Rotavirüs, çocuklarda en sık görülen ve elektrolit düzensizliği, şiddetli dehidratasyon, hipovolemik şok ve ölümle sonuçlanabilen akut gastroenterit nedenidir. Kesin tanı için geliştirilmiş serolojik yöntemler mevcut olsa da bu yöntemlere ulaşmak her zaman kolay olmayabilir. Bu çalışma rotavirüs tanısına yardımcı olan parametreleri değerlendirmeyi amaçlamaktadır. Gereç ve Yöntemler: Akut gastroenterit nedeniyle hastanemize başvuran 1 ay-18 yaş arası 1539 çocuğu retrospektif olarak inceledik. Hastalar rotavirüs pozitif ve rotavirüs negatif olarak iki gruba ayrıldı. RV-pozitif grupta 745 hasta ve RV-negatif grupta 794 hasta vardı. Bulgular: Ortalama RBC p0,005, Hb p0,001, Htc p0,001, MCV p0,001, nötrofil p0,001, platelet lenfosit oranı p0,003, nötrofil lenfosit oranı p0,001, eozinofil lenfosit oranı p0,001 seviyeleri RV-pozitif grupta anlamlı olarak daha düşüktü. Ortalama platelet düzeyi p0,005 ve ortalama lenfosit düzeyi p0,001 RV-pozitif grupta anlamlı olarak daha yüksekti. Sonuç: Rotavirüs gastroenteritinde birçok hematolojik parametre etkilenmiştir. RBC, Hb, Htc, MCV, ortalama trombosit düzeyi, ortalama nötrofil düzeyi, ortalama lenfosit düzeyi, trombositlenfosit oranı, nötrofillenfosit oranı, eozinofillenfosit oranı ve rotavirüs gastroenteriti için destekleyici olabilir.

Makale detayları

Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea

Yazarlar:

Zehra Aydın | Habip Almış | İbrahim Hakan Bucak | Mehmet Turğut

Yayıncı:

Istanbul University

Ana Başlıklar:

Çocuk Sağlığı ve Hastalıkları

Dergi:

Çocuk Dergisi Vol.23 Issue 2, pp.113-118

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293958

pISSN:

1308-8491

Rotavirus

Gastroenteritis

ChildRotavirüs

Gastroenterit

Çocuk

Sayı

Makale detayları

Evaluation of Children With Rotavirus Positive And Rotavirus Negative Diarrhea

Yazarlar: Zehra Aydın | Habip Almış | İbrahim Hakan Bucak | Mehmet Turğut

Yayıncı: Istanbul University

Ana Başlıklar: Çocuk Sağlığı ve Hastalıkları

Dergi: Çocuk Dergisi Vol.23 Issue 2, pp.113-118

Belge Tipi: Makale

Yayın Tarihi: 6/2023

Belge Dili: İngilizce

Document ID (Org No.): 2001293958

pISSN: 1308-8491

Rotavirus

Gastroenteritis

ChildRotavirüs

Gastroenterit

Çocuk

Sayı

Yazarlar:

Zehra Aydın | Habip Almış | İbrahim Hakan Bucak | Mehmet Turğut

Yayıncı:

Istanbul University

Ana Başlıklar:

Çocuk Sağlığı ve Hastalıkları

Dergi:

Çocuk Dergisi Vol.23 Issue 2, pp.113-118

Belge Tipi:

Makale

Yayın Tarihi:

6/2023

Belge Dili:

İngilizce

Document ID (Org No.):

2001293958

pISSN:

1308-8491