In vitro Antidiabetic Activity of Seven Medicinal Plants Naturally Growing in Turkey

Ebru DEVECI; Gulsen TEL CAYAN; Mehmet Emin DURU

Makale detayları

In vitro Antidiabetic Activity of Seven Medicinal Plants Naturally Growing in Turkey

Yazarlar:

Ebru DEVECI | Gulsen TEL CAYAN | Mehmet Emin DURU

Yayıncı:

Istanbul University

Dergi:

European Journal of Biology 2020 Vol.79 Issue 1, pp.23-28

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000424398

eISSN:

2618-6144

pISSN:

2602-2575

Özet:

 

Objective: Diabetes mellitus is a worldwide metabolic/endocrine disease that causes major medical problems. One of the most important strategies used in the therapy of the diabetes mellitus is the use of inhibition of α-glucosidase and α-amylase enzymes. Therefore, this study aimed to investigate antidiabetic activities of the hexane and methanol extracts of the medicinal plants from Turkey. Materials and Methods: The hexane and methanol extracts of Euphorbia helioscopia, Ferula elaeochytris, Sideritis albiflora, Sideritis stricta, Sideritis pisidica, Sideritis leptoclada, Salvia chionantha plants were prepared at room temperature. Antidiabetic activities of the extracts on α-glucosidase and α-amylase enzymes were determined. Results: S. pisidica hexane extract exhibited higher α-amylase inhibitory activity than acarbose (96.60±0.08 %) used as a standard with an inhibition value of 97.99±0.79 % at 1000 µg/mL concentration. In terms of α-glucosidase inhibitory activities, the extracts were ranked in the following order: F. elaeochytris hexane extract > S. leptoclada hexane extract > S. stricta hexane extract > E. helioscopia hexane extract. Conclusion: In this study, antidiabetic activities of the extracts on α-glucosidase and α-amylase enzymes of the studied medicinal plants were screened for the first time. It has been suggested that S. pisidica hexane extract can be used as antidiabetic agent.

Makale detayları

In vitro Antidiabetic Activity of Seven Medicinal Plants Naturally Growing in Turkey

Yazarlar: Ebru DEVECI | Gulsen TEL CAYAN | Mehmet Emin DURU

Yayıncı: Istanbul University

Dergi: European Journal of Biology 2020 Vol.79 Issue 1, pp.23-28

Belge Tipi: Makale

Yayın Tarihi: 6/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000424398

eISSN: 2618-6144

pISSN: 2602-2575

Sayı

Yazarlar:

Ebru DEVECI | Gulsen TEL CAYAN | Mehmet Emin DURU

Yayıncı:

Istanbul University

Dergi:

European Journal of Biology 2020 Vol.79 Issue 1, pp.23-28

Belge Tipi:

Makale

Yayın Tarihi:

6/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000424398

eISSN:

2618-6144

pISSN:

2602-2575