Challenges, Prognosis and Outcomes of Surgical Resection for Hepatic Alveolar Echinococcosis: A Single Centre Experience

Ahmet Rencuzogulları; Ismail Soner Koltas; Atilgan Tolga Akcam; Abdullah Ulku; Orcun Yalav; Ahmet Gokhan Saritas; Kubilay Dalcı; Ismail Cem Eray

Makale detayları

Challenges, Prognosis and Outcomes of Surgical Resection for Hepatic Alveolar Echinococcosis: A Single Centre Experience

Yazarlar:

Ahmet Rencuzogulları | Ismail Soner Koltas | Atilgan Tolga Akcam | Abdullah Ulku | Orcun Yalav | Ahmet Gokhan Saritas | Kubilay Dalcı | Ismail Cem Eray

Yayıncı:

Dicle University

Dergi:

Dicle Medical Journal 2017 Vol.44 Issue 2, pp.183-190

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000946944

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945

Anahtar kelimeler:

alveolar echinococcosis; hepatic resection; Echinococcus multilocularis

Özet:

 


Objective: Alveolar echinococcosis (AE) is an aggressive and potentially fatal infection, which affects the liverprimarily and presents as a tumor-like lesion. Outcomes associated with surgical procedures for this infection havebeen rarely reported. In the present study, we aimed to evaluate long-term surgical treatment outcomes associatedwith hepatic AE.Methods: Between 2001 and 2013, the management and outcomes of twelve consecutive hepatic AE patients whowere considered feasible for complete hepatic resection with/without metastasectomy were described. In all patients,pre-operative diagnosis of AE was based on clinical findings, imaging studies, and serological tests. Antibodies againstantigens of Echinococcus multilocularis metacestodes were screened as specific markers for the serological diagnosisof AE by Western blot. The oral albendazole protocol was administered for hepatic AE patients who had completeresection.Results: Twelve patients (F/M=7/5) underwent complete resection for pathologically confirmed hepatic AE duringthe study period. Median follow-up was 82 (32-164) months. The most common initial symptom was abdominal pain(n=9) followed by jaundice (n=4). Four patients had metastasis: Brain, surrenal, splenic and colon. One patient waslost due to massive pulmonary emboli despite appropriate interventions. All other complications that emerged weretreated successfully.Conclusion: Long-term favorable outcomes can be achieved by complete surgical resection followed bychemotherapy with albendazole in advanced hepatic AE cases.

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Makale detayları

Challenges, Prognosis and Outcomes of Surgical Resection for Hepatic Alveolar Echinococcosis: A Single Centre Experience

Yazarlar: Ahmet Rencuzogulları | Ismail Soner Koltas | Atilgan Tolga Akcam | Abdullah Ulku | Orcun Yalav | Ahmet Gokhan Saritas | Kubilay Dalcı | Ismail Cem Eray

Yayıncı: Dicle University

Dergi: Dicle Medical Journal 2017 Vol.44 Issue 2, pp.183-190

Belge Tipi: Makale

Yayın Tarihi: 6/2017

Belge Dili: Türkçe

Document ID (Org No.): 2000946944

Sıklık: Üç Aylık

eISSN: 1308-9889

pISSN: 1300-2945

alveolar echinococcosis; hepatic resection; Echinococcus multilocularis

Sayı

Yazarlar:

Ahmet Rencuzogulları | Ismail Soner Koltas | Atilgan Tolga Akcam | Abdullah Ulku | Orcun Yalav | Ahmet Gokhan Saritas | Kubilay Dalcı | Ismail Cem Eray

Yayıncı:

Dicle University

Dergi:

Dicle Medical Journal 2017 Vol.44 Issue 2, pp.183-190

Belge Tipi:

Makale

Yayın Tarihi:

6/2017

Belge Dili:

Türkçe

Document ID (Org No.):

2000946944

Sıklık:

Üç Aylık

eISSN:

1308-9889

pISSN:

1300-2945