BIOAPYGIN HERBAL OINTMENT AND PESSARIES COMPARED TO ACIDOSALUS PESSARIES AND VAGINAL PROBIOTIC IN THE TREATMENT OF VULVO-VAGINAL DISORDERS

Višnja OREŠČANİN; štefica FİNDRİ GUŠTEK

doi:https://doi.org/10.38093/cupmap.552083

Makale detayları

BIOAPYGIN HERBAL OINTMENT AND PESSARIES COMPARED TO ACIDOSALUS PESSARIES AND VAGINAL PROBIOTIC IN THE TREATMENT OF VULVO-VAGINAL DISORDERS

Yazarlar:

Višnja OREŠČANİN | štefica FİNDRİ GUŠTEK

Yayıncı:

Nazım ŞEKEROĞLU

Dergi:

Current Perspectives on Medicinal and Aromatic Plants 2019 Vol.2 Issue 1, pp.11-22

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000925622

Sıklık:

İki Yıllık

eISSN:

2667-5722

pISSN:

2619-9645

DOI:

https://doi.org/10.38093/cupmap.552083

Özet:

 





Objective / Purpose: The objective of the study was
assessment of the clinical efficacy and safety of BioapigynÒ vaginal ointment and pessaries
compared to AcidosalusÒ pessaries and vaginal probiotic in
alleviating vulvo-vaginal disorders. 




Materials and
methods: 124 females
were randomly selected into four groups (each of 31 participants) and treated
once a day for ten days with: A) BioapigynÒ vaginal pessaries (one pessary per
day); B) 2.5 mL of BioapyginÒ vaginal ointment; C) AcidosalusÒ vaginal pessaries (one pessary per
day); D) 2.5 mL of AcidosalusÒ vaginal probiotic. All the patients were subjected to
gynecological examination, measurement of vaginal pH, Pap test, native and KOH
test, self-assessment and clinical assessment of the symptoms at baseline and
following the therapy. 




Results: Following the treatment with BioapiginÒ vaginal ointment, BioapigynÒ
pessaries, AcidosalusÒ pessaries, AcidosalusÒ vaginal
probiotic the total score of vulvo-vaginal disorders decreased for 85.2%,
88.9%, 82.7% and 78%, respectively and vaginal pH decreased between 9.1% and 14.3%.
Native test showed normalization of the vaginal flora following the treatment
with all four products with no significant difference among the products.


Conclusion/Discussion:
Both BioapigynÒ and
AcidosalusÒ products
were highly efficient in alleviation of vulvo-vaginal disorders. The products
created unfavorable conditions for pathogenic growth through the lowering of
vaginal pH value, promoting the growth of lactobacilli, creating the environment
with low water activity and creating a protective layer on the damaged mucosa
that creates a physical barrier to the entrance of the pathogens into the cells
and enables the recovery of the vaginal mucosa. 

.

Makale detayları

BIOAPYGIN HERBAL OINTMENT AND PESSARIES COMPARED TO ACIDOSALUS PESSARIES AND VAGINAL PROBIOTIC IN THE TREATMENT OF VULVO-VAGINAL DISORDERS

Yazarlar: Višnja OREŠČANİN | štefica FİNDRİ GUŠTEK

Yayıncı: Nazım ŞEKEROĞLU

Dergi: Current Perspectives on Medicinal and Aromatic Plants 2019 Vol.2 Issue 1, pp.11-22

Belge Tipi: Makale

Yayın Tarihi: 7/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000925622

Sıklık: İki Yıllık

eISSN: 2667-5722

pISSN: 2619-9645

DOI: https://doi.org/10.38093/cupmap.552083

Sayı

Yazarlar:

Višnja OREŠČANİN | štefica FİNDRİ GUŠTEK

Yayıncı:

Nazım ŞEKEROĞLU

Dergi:

Current Perspectives on Medicinal and Aromatic Plants 2019 Vol.2 Issue 1, pp.11-22

Belge Tipi:

Makale

Yayın Tarihi:

7/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000925622

Sıklık:

İki Yıllık

eISSN:

2667-5722

pISSN:

2619-9645

DOI:

https://doi.org/10.38093/cupmap.552083