Nitrous oxide anesthesia in children for MRI: a comparison with isoflurane and halothane

Mehmet Emin ORHAN; Ferruh BİLGİN; Oğuz KILIÇKAYA; Abdulkadir ATIM; Ercan KURT

Makale detayları

Nitrous oxide anesthesia in children for MRI: a comparison with isoflurane and halothane

Yazarlar:

Mehmet Emin ORHAN | Ferruh BİLGİN | Oğuz KILIÇKAYA | Abdulkadir ATIM | Ercan KURT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 3, pp.387-396

Belge Tipi:

Makale

Yayın Tarihi:

2/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754683

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Anahtar kelimeler:

Özet:

 

To compare the anesthetic effects of nitrous oxide, isoflurane, and halothane on hemodynamic stability and recovery characteristics in pediatric patients during magnetic resonance imaging (MRI).  Materials and methods: The present study includes 60 ASA I-II children aged 1-12 years undergoing MRI. After endotracheal intubation, patients were randomly assigned into 1 of 3 anesthetic groups. Group N (n = 20) received nitrous oxide and oxygen (N2O:O2 60:40), Group I (n = 20) received 0.5% isoflurane and oxygen, Group H (n = 20) received 0.5% halothane and oxygen to maintain anesthesia. At the completion of the procedure, inhalation anesthetic was discontinued. Extubation, emergence, recovery times, and adverse events were recorded throughout the duration of the procedure. Results: There was no significant difference in the demographic data among the groups. In the nitrous oxide group 5 children (25%), in the halothane group 2 children (10%), and in the isoflurane group 1 child (5%) moved during MRI and supplemental inhalation anesthesia was required for these patients. Emergence time after nitrous oxide anesthesia was slightly shorter than after isoflurane anesthesia (3.15 ± 2.56 min compared with 4.65 ± 2.64 min, P = 0.162) but significantly shorter than after halothane anesthesia (5.35 ± 2.47 min, P = 0.023). Early recovery time after nitrous oxide and isoflurane anesthesia was significantly more rapid than after halothane anesthesia (4.60 ± 2.58 min and 3.65 ± 1.63 min compared with 7.00 ± 2.15 min, P < 0.05).  Conclusion: After induction with propofol, nitrous oxide may provide anesthesia for MRI in pre-medicated children. However, complete immobility was not achieved in all patients with nitrous oxide alone. Nitrous oxide and isoflurane resulted in faster emergence and recovery than halothane, but there was no significant difference between nitrous oxide and isoflurane. Discharge times from the hospital were similar for all 3 groups.

 

To compare the anesthetic effects of nitrous oxide, isoflurane, and halothane on hemodynamic stability and recovery characteristics in pediatric patients during magnetic resonance imaging (MRI).  Materials and methods: The present study includes 60 ASA I-II children aged 1-12 years undergoing MRI. After endotracheal intubation, patients were randomly assigned into 1 of 3 anesthetic groups. Group N (n = 20) received nitrous oxide and oxygen (N2O:O2 60:40), Group I (n = 20) received 0.5% isoflurane and oxygen, Group H (n = 20) received 0.5% halothane and oxygen to maintain anesthesia. At the completion of the procedure, inhalation anesthetic was discontinued. Extubation, emergence, recovery times, and adverse events were recorded throughout the duration of the procedure. Results: There was no significant difference in the demographic data among the groups. In the nitrous oxide group 5 children (25%), in the halothane group 2 children (10%), and in the isoflurane group 1 child (5%) moved during MRI and supplemental inhalation anesthesia was required for these patients. Emergence time after nitrous oxide anesthesia was slightly shorter than after isoflurane anesthesia (3.15 ± 2.56 min compared with 4.65 ± 2.64 min, P = 0.162) but significantly shorter than after halothane anesthesia (5.35 ± 2.47 min, P = 0.023). Early recovery time after nitrous oxide and isoflurane anesthesia was significantly more rapid than after halothane anesthesia (4.60 ± 2.58 min and 3.65 ± 1.63 min compared with 7.00 ± 2.15 min, P < 0.05).  Conclusion: After induction with propofol, nitrous oxide may provide anesthesia for MRI in pre-medicated children. However, complete immobility was not achieved in all patients with nitrous oxide alone. Nitrous oxide and isoflurane resulted in faster emergence and recovery than halothane, but there was no significant difference between nitrous oxide and isoflurane. Discharge times from the hospital were similar for all 3 groups.

Makale detayları

Nitrous oxide anesthesia in children for MRI: a comparison with isoflurane and halothane

Yazarlar:

Mehmet Emin ORHAN | Ferruh BİLGİN | Oğuz KILIÇKAYA | Abdulkadir ATIM | Ercan KURT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 3, pp.387-396

Belge Tipi:

Makale

Yayın Tarihi:

2/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754683

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Magnetic resonance imaging

pediatrics

anesthesia

nitrous oxide

isoflurane

halothane

recovery

Sayı

Makale detayları

Yazarlar: Mehmet Emin ORHAN | Ferruh BİLGİN | Oğuz KILIÇKAYA | Abdulkadir ATIM | Ercan KURT

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2011 Vol.41 Issue 3, pp.387-396

Belge Tipi: Makale

Yayın Tarihi: 2/2011

Belge Dili: Türkçe

Document ID (Org No.): 2000754683

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Mehmet Emin ORHAN | Ferruh BİLGİN | Oğuz KILIÇKAYA | Abdulkadir ATIM | Ercan KURT

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2011 Vol.41 Issue 3, pp.387-396

Belge Tipi:

Makale

Yayın Tarihi:

2/2011

Belge Dili:

Türkçe

Document ID (Org No.):

2000754683

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144