Photochemically-Induced Fluorescence Properties and Determination of Flufenamic Acid, a Non-Steroidal Anti-Inflammatory Drug, in Urine and Pharmaceutical Preparation

Leila Bettaieb And Jean-jacques AARON

Makale detayları

Photochemically-Induced Fluorescence Properties and Determination of Flufenamic Acid, a Non-Steroidal Anti-Inflammatory Drug, in Urine and Pharmaceutical Preparation

Yazarlar:

Leila Bettaieb And Jean-jacques AARON

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2001 Vol.25 Issue 2, pp.165-171

Belge Tipi:

Makale

Yayın Tarihi:

1/2001

Belge Dili:

İngilizce

Document ID (Org No.):

2000730129

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

The photochemically-induced fluorescence (PIF) properties of flufenamic acid (FF), a non-steroidal anti-inflammatory drug (NSAID) were investigated in   acidic (pH 1.0) aqueous solutions at room temperature. An optimization   procedure, including the effects of UV irradiation time, pH and solvent, was   established for the determination of FF. A linear logarithmic calibration   plot was obtained over a wide concentration range of four orders of   magnitude. A low limit of detection of 0.14 ng/mL was found. The relative   standard deviation (RSD) was 6.6% . The PIF method was applied to the   quantitative analysis of FF in urine and in a pharmaceutical preparation   with satisfactory recovery values.

 

The photochemically-induced fluorescence (PIF) properties of flufenamic acid (FF), a non-steroidal anti-inflammatory drug (NSAID) were investigated in   acidic (pH 1.0) aqueous solutions at room temperature. An optimization   procedure, including the effects of UV irradiation time, pH and solvent, was   established for the determination of FF. A linear logarithmic calibration   plot was obtained over a wide concentration range of four orders of   magnitude. A low limit of detection of 0.14 ng/mL was found. The relative   standard deviation (RSD) was 6.6% . The PIF method was applied to the   quantitative analysis of FF in urine and in a pharmaceutical preparation   with satisfactory recovery values.

Makale detayları

Photochemically-Induced Fluorescence Properties and Determination of Flufenamic Acid, a Non-Steroidal Anti-Inflammatory Drug, in Urine and Pharmaceutical Preparation

Yazarlar: Leila Bettaieb And Jean-jacques AARON

Yayıncı: TUBITAK

Ana Başlıklar: Uygulamalı fizik

Dergi: Turkish Journal of Chemistry 2001 Vol.25 Issue 2, pp.165-171

Belge Tipi: Makale

Yayın Tarihi: 1/2001

Belge Dili: İngilizce

Document ID (Org No.): 2000730129

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Leila Bettaieb And Jean-jacques AARON

Yayıncı:

TUBITAK

Ana Başlıklar:

Uygulamalı fizik

Dergi:

Turkish Journal of Chemistry 2001 Vol.25 Issue 2, pp.165-171

Belge Tipi:

Makale

Yayın Tarihi:

1/2001

Belge Dili:

İngilizce

Document ID (Org No.):

2000730129

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527