Prospective analysis of optic nerve diameter and NSE values in patients with refractory headaches

Naciye Orçan; Ayça Açıkalın; Gülçin Dağlıoğlu; Ömer Taşkın; Rana Dişel; Özge Bakışkan Tombul; Merve Türker

Makale detayları

Prospective analysis of optic nerve diameter and NSE values in patients with refractory headaches

Yazarlar:

Naciye Orçan | Ayça Açıkalın | Gülçin Dağlıoğlu | Ömer Taşkın | Rana Dişel | Özge Bakışkan Tombul | Merve Türker

Yayıncı:

Cukurova University

Ana Başlıklar:

Acil Tıp | Tanı Radyografisi | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.121-129

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314681

pISSN:

2602-3032

Anahtar kelimeler:

Özet:

 Purpose: This study aims to investigate the usability of ultrasonographic optic nerve diameter measurement and plasma neuron-specific enolase NSE levels in detecting secondary causes of headaches in patients with refractory headaches in emergency department. Materials and Methods: The study was conducted in a university-based adult emergency department over 3 years. Sixty-six consecutive patients presenting to the emergency department with refractory headaches and 50 healthy volunteers for the control group were included. Information recorded included the duration of complaints, type and location of headache, symptoms, co-morbidities, results of imaging studies, optic nerve diameters, results of lactate, arterial blood gas and NSE levels. Results: A total of 66 patients were included, comprising 33 females. The mean age was 43.05  17.06 years. Secondary causes of headache were identified in 45 patients 68.2. Evaluation of ultrasonographic optic nerve diameter revealed that 17 25.8 right and 21 31.8 left optic nerve diameters were 5 mm. Optic nerve diameter values were significantly higher in patients diagnosed with secondary headache compared to those with primary headache, with no statistically significant difference observed in NSE values. Lactate levels in patients with secondary headaches were significantly higher than those in patients with primary headaches. Conclusion: In patients admitted to the emergency department with refractory headaches and normal imaging, ultrasonographic optic nerve diameter measurement may be preferred as an easily accessible method to guide the detection of secondary causes. NSE was not an effective in the early selection of patients with secondary headaches.

 Purpose: This study aims to investigate the usability of ultrasonographic optic nerve diameter measurement and plasma neuron-specific enolase NSE levels in detecting secondary causes of headaches in patients with refractory headaches in emergency department. Materials and Methods: The study was conducted in a university-based adult emergency department over 3 years. Sixty-six consecutive patients presenting to the emergency department with refractory headaches and 50 healthy volunteers for the control group were included. Information recorded included the duration of complaints, type and location of headache, symptoms, co-morbidities, results of imaging studies, optic nerve diameters, results of lactate, arterial blood gas and NSE levels. Results: A total of 66 patients were included, comprising 33 females. The mean age was 43.05  17.06 years. Secondary causes of headache were identified in 45 patients 68.2. Evaluation of ultrasonographic optic nerve diameter revealed that 17 25.8 right and 21 31.8 left optic nerve diameters were 5 mm. Optic nerve diameter values were significantly higher in patients diagnosed with secondary headache compared to those with primary headache, with no statistically significant difference observed in NSE values. Lactate levels in patients with secondary headaches were significantly higher than those in patients with primary headaches. Conclusion: In patients admitted to the emergency department with refractory headaches and normal imaging, ultrasonographic optic nerve diameter measurement may be preferred as an easily accessible method to guide the detection of secondary causes. NSE was not an effective in the early selection of patients with secondary headaches.

 Purpose: This study aims to investigate the usability of ultrasonographic optic nerve diameter measurement and plasma neuron-specific enolase NSE levels in detecting secondary causes of headaches in patients with refractory headaches in emergency department. Materials and Methods: The study was conducted in a university-based adult emergency department over 3 years. Sixty-six consecutive patients presenting to the emergency department with refractory headaches and 50 healthy volunteers for the control group were included. Information recorded included the duration of complaints, type and location of headache, symptoms, co-morbidities, results of imaging studies, optic nerve diameters, results of lactate, arterial blood gas and NSE levels. Results: A total of 66 patients were included, comprising 33 females. The mean age was 43.05  17.06 years. Secondary causes of headache were identified in 45 patients 68.2. Evaluation of ultrasonographic optic nerve diameter revealed that 17 25.8 right and 21 31.8 left optic nerve diameters were 5 mm. Optic nerve diameter values were significantly higher in patients diagnosed with secondary headache compared to those with primary headache, with no statistically significant difference observed in NSE values. Lactate levels in patients with secondary headaches were significantly higher than those in patients with primary headaches. Conclusion: In patients admitted to the emergency department with refractory headaches and normal imaging, ultrasonographic optic nerve diameter measurement may be preferred as an easily accessible method to guide the detection of secondary causes. NSE was not an effective in the early selection of patients with secondary headaches.

 Amaç: Bu çalışmanın amacı, acil serviste dirençli baş ağrısı olan hastalarda ultrasonografik optik sinir çapı ölçümü ve plazma nöron spesifik enolaz NSE düzeyinin ikincil baş ağrısı nedenlerini saptamada kullanılabilirliğini araştırmaktır. Gereç ve Yöntem: Çalışma, bir üniversite hastanesi erişkin acil servisinde, 3 yılı aşkın bir süre boyunca yürütülmüştür. Acil servise dirençli baş ağrısı ile başvuran 66 hasta ve kontrol grubu olarak 50 sağlıklı gönüllü çalışmaya dahil edilmiştir. Hastaların şikayetlerinin süresi, baş ağrısının tipi ve yeri, semptomları, eşlik eden hastalıkları, görüntüleme sonuçları, optik sinir çapları, laktat, arteriyel kan gazı ve NSE düzeyleri kaydedilmiştir. Bulgular: Çalışmaya 33ü kadın olmak üzere toplam 66 hasta dahil edildi. Yaş ortalaması 43.0517.06 idi. Hastaların 45inde 68.2 ikincil baş ağrısı nedenleri saptandı. Ultrasonografik optik sinir çapı değerlendirildiğinde, 17 25.8 sağ ve 21 31.8 sol optik sinir çapının 5 mm olduğu tespit edildi. Sekonder baş ağrısı tanısı alan hastalarda sağ ve sol optik sinir çapı değerleri anlamlı olarak yüksek bulunurken, NSE değerlerinde istatistiksel olarak anlamlı bir fark bulunmadı. Sekonder baş ağrısı olan hastalarda laktat düzeyleri primer baş ağrısı olan hastalara göre istatistiksel olarak anlamlı derecede yüksekti. Sonuç: Dirençli baş ağrısı ile acil servise başvuran ve görüntülemesi normal olan hastalarda, ultrasonografik optik sinir çapı ölçümü, ikincil nedenlerin saptanmasına rehberlik etmek için kolay erişilebilir bir yöntem olarak tercih edilebilir. NSE, ikincil baş ağrısı olan hastaların erken seçiminde etkili bir yöntem değildir.

Makale detayları

Prospective analysis of optic nerve diameter and NSE values in patients with refractory headaches

Yazarlar:

Naciye Orçan | Ayça Açıkalın | Gülçin Dağlıoğlu | Ömer Taşkın | Rana Dişel | Özge Bakışkan Tombul | Merve Türker

Yayıncı:

Cukurova University

Ana Başlıklar:

Acil Tıp | Tanı Radyografisi | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.121-129

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314681

pISSN:

2602-3032

Headache

Neuron specific enolase

optic nerve diameterBaş ağrısı

nöron spesifik enolaz

optik sinir çapı

Sayı

Makale detayları

Prospective analysis of optic nerve diameter and NSE values in patients with refractory headaches

Yazarlar: Naciye Orçan | Ayça Açıkalın | Gülçin Dağlıoğlu | Ömer Taşkın | Rana Dişel | Özge Bakışkan Tombul | Merve Türker

Yayıncı: Cukurova University

Ana Başlıklar: Acil Tıp | Tanı Radyografisi | Nöroloji ve Nöromüsküler Hastalıklar

Dergi: Cukurova Medical Journal Vol.49 Issue 1, pp.121-129

Belge Tipi: Makale

Yayın Tarihi: 3/2024

Belge Dili: İngilizce

Document ID (Org No.): 2001314681

pISSN: 2602-3032

Headache

Neuron specific enolase

optic nerve diameterBaş ağrısı

nöron spesifik enolaz

optik sinir çapı

Sayı

Yazarlar:

Naciye Orçan | Ayça Açıkalın | Gülçin Dağlıoğlu | Ömer Taşkın | Rana Dişel | Özge Bakışkan Tombul | Merve Türker

Yayıncı:

Cukurova University

Ana Başlıklar:

Acil Tıp | Tanı Radyografisi | Nöroloji ve Nöromüsküler Hastalıklar

Dergi:

Cukurova Medical Journal Vol.49 Issue 1, pp.121-129

Belge Tipi:

Makale

Yayın Tarihi:

3/2024

Belge Dili:

İngilizce

Document ID (Org No.):

2001314681

pISSN:

2602-3032