Evaluation of Acute and Subacute Toxicity of ISY-CP® Food Herbal Mixture in Rats

Mustafa YAŞAR; Oğuzhan ŞENOĞUL; Beste KARADENİZ; Ali GÖK; Pınar AĞYAR YOLDAŞ; Kağan AĞAN

Makale detayları

Evaluation of Acute and Subacute Toxicity of ISY-CP® Food Herbal Mixture in Rats

Yazarlar:

Mustafa YAŞAR | Oğuzhan ŞENOĞUL | Beste KARADENİZ | Ali GÖK | Pınar AĞYAR YOLDAŞ | Kağan AĞAN

Yayıncı:

Duzce University

Ana Başlıklar:

Hastalıklar

Dergi:

International Journal of Traditional and Complementary Medicine Research 2020 Vol.1 Issue 2, pp.54-60

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000477506

Sıklık:

Üç Yıllık

pISSN:

2717-7491

Özet:

 

Objective: Recently, there is a growing interest in medicinal and aromatic plants also the treatment methods by using these plants in traditional and complementary medicine. On the other hand, possible toxicities of medicinal and aromatic plants has lately begun to be researched and it is extremely important to cognize these possibilities for human consumption. Therefore, a research has been conducted to understand the acute/subacute toxicity characteristics of a plant based herbal mixture, ISY-CP® used in remember regeneration therapy method (RTM) in rats.  The product contains a mixture of nettle leaves (Urtica dioica), yarrow (Achillea millefolium), thyme (Thymus vulgaris) and horsetail (Equisetum arvense) plants. The aim of this research was to examine the effects of ISY-CP® herbal mixture in term of toxicity. 
Material-Method: In the experimental design, 32 female rats were divided into 4 groups (control, acute, subacute and post-subacute). In order to observe acute and subacute toxicity, clinical observations were performed and the biochemical, hematological and histopathological parameters of the animals were evaluated at the end of the application. 
Results: According to the results obtained from the study, there were not found significant differences in biochemical, hematological and histopathological evaluations between the control and the application groups. Only phorphorus data is statistically different between subacute toxicity group and control group.
Conclusion: In our study, the acute and subacute toxic effects of ISY-CP® herbal mixture’s doses used in this study were not observed.

Makale detayları

Evaluation of Acute and Subacute Toxicity of ISY-CP® Food Herbal Mixture in Rats

Yazarlar: Mustafa YAŞAR | Oğuzhan ŞENOĞUL | Beste KARADENİZ | Ali GÖK | Pınar AĞYAR YOLDAŞ | Kağan AĞAN

Yayıncı: Duzce University

Ana Başlıklar: Hastalıklar

Dergi: International Journal of Traditional and Complementary Medicine Research 2020 Vol.1 Issue 2, pp.54-60

Belge Tipi: Makale

Yayın Tarihi: 8/2020

Belge Dili: İngilizce

Document ID (Org No.): 2000477506

Sıklık: Üç Yıllık

pISSN: 2717-7491

Sayı

Yazarlar:

Mustafa YAŞAR | Oğuzhan ŞENOĞUL | Beste KARADENİZ | Ali GÖK | Pınar AĞYAR YOLDAŞ | Kağan AĞAN

Yayıncı:

Duzce University

Ana Başlıklar:

Hastalıklar

Dergi:

International Journal of Traditional and Complementary Medicine Research 2020 Vol.1 Issue 2, pp.54-60

Belge Tipi:

Makale

Yayın Tarihi:

8/2020

Belge Dili:

İngilizce

Document ID (Org No.):

2000477506

Sıklık:

Üç Yıllık

pISSN:

2717-7491