Preparation of αα\alpha -hydroxyphenylacetic acid with cyclodextrins as an   effective phase-transfer catalyst and its reaction mechanism

Bing Ren TIAN; Rui Xia ZHANG; Hui Min CHU; Qing HUANG; Zhi Zhong WANG

Makale detayları

Preparation of αα\alpha -hydroxyphenylacetic acid with cyclodextrins as an effective phase-transfer catalyst and its reaction mechanism

Yazarlar:

Bing Ren TIAN | Rui Xia ZHANG | Hui Min CHU | Qing HUANG | Zhi Zhong WANG

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2019 Vol.43 Issue 1, pp.359-368

Belge Tipi:

Makale

Yayın Tarihi:

1/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000725908

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527

Özet:

 

An effective procedure for the synthesis of αα\alpha   -hydroxyphenylacetic acid with cyclodextrin (CD) catalysts was developed.   The phase-transfer catalyst types, catalyst loadings, reaction times,   reaction temperatures, and substrate molar ratios were investigated to   optimize the reaction conditions. In addition, the factors that affect the   reaction were studied, and the relationship between benzaldehyde and ββ\beta   -cyclodextrin (ββ\beta -CD) was analyzed through 2D-ROESY. The equilibrium   constant when ββ\beta -CD was used as the catalyst was calculated. The   results indicated that ββ\beta -CD is the optimal catalyst for the reported   reaction (yield: 69.08%). Furthermore, the mechanism underlying the   reported reaction was proposed.

Makale detayları

Preparation of αα\alpha -hydroxyphenylacetic acid with cyclodextrins as an effective phase-transfer catalyst and its reaction mechanism

Yazarlar: Bing Ren TIAN | Rui Xia ZHANG | Hui Min CHU | Qing HUANG | Zhi Zhong WANG

Yayıncı: TUBITAK

Dergi: Turkish Journal of Chemistry 2019 Vol.43 Issue 1, pp.359-368

Belge Tipi: Makale

Yayın Tarihi: 1/2019

Belge Dili: Türkçe

Document ID (Org No.): 2000725908

Sıklık: İki Aylık

eISSN: 1303-6130

pISSN: 1300-0527

Sayı

Yazarlar:

Bing Ren TIAN | Rui Xia ZHANG | Hui Min CHU | Qing HUANG | Zhi Zhong WANG

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Chemistry 2019 Vol.43 Issue 1, pp.359-368

Belge Tipi:

Makale

Yayın Tarihi:

1/2019

Belge Dili:

Türkçe

Document ID (Org No.):

2000725908

Sıklık:

İki Aylık

eISSN:

1303-6130

pISSN:

1300-0527