Evaluation of cancer risk in patients with periodontal diseases

Deniz Can GÜVEN; Ömer DİZDAR; Abdullah Cevdet AKMAN; Ayşe Ezel BERKER; Emre YEKEDÜZ; Furkan CEYLAN; Batuhan BAŞPINAR; İlgin AKBIYIK; Burak Yasin AKTAŞ; Deniz YÜCE; Mustafa ERMAN; Kadir Mutlu HAYRAN

Makale detayları

Evaluation of cancer risk in patients with periodontal diseases

Yazarlar:

Deniz Can GÜVEN | Ömer DİZDAR | Abdullah Cevdet AKMAN | Ayşe Ezel BERKER | Emre YEKEDÜZ | Furkan CEYLAN | Batuhan BAŞPINAR | İlgin AKBIYIK | Burak Yasin AKTAŞ | Deniz YÜCE | Mustafa ERMAN | Kadir Mutlu HAYRAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.826-831

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750106

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144

Özet:

 

Background/aim: In this study, we aimed to assess the cancer risk among patients with periodontal disease.Materials and methods: Patients diagnosed with periodontal diseases at Hacettepe University between 2007 and 2012 were included and  data  on  the  diagnosis  of  any  cancer  after  periodontal  disease  were  collected  from  patient  files.  The  age-  and  sex-standardized  incidence rates (SIRs) were calculated using Turkish National Cancer Registry 2013 data.Results: A total of 5199 patients were included. Median follow-up was 7.2 years. Patients with periodontal diseases had 17% increased risk of cancer compared with the expected counts for the corresponding age and sex groups (SIR: 1.17; 95% CI: 1.04-1.3, P = 0.006). The increased cancer risk was statistically significant in women (SIR: 1.24; 95% CI: 1.05-1.45, P = 0.008) but not in men. Among women with periodontal disease, the risks of breast cancer (SIR: 2.19) and head and neck cancer (SIR: 4.71) were significantly increased. Among men, the risks of prostate cancer (SIR: 1.84), head and neck cancer (SIR: 3.55), and hematological cancers (SIR: 1.76) were significantly increased.Conclusion:  This  study  showed  that  periodontal  diseases  were  associated  with  increased  risk  of  several  cancers.  Besides  other  well-known benefits for health, the provision of oral/dental health should be considered and employed as a cancer prevention measure.

Makale detayları

Evaluation of cancer risk in patients with periodontal diseases

Yazarlar: Deniz Can GÜVEN | Ömer DİZDAR | Abdullah Cevdet AKMAN | Ayşe Ezel BERKER | Emre YEKEDÜZ | Furkan CEYLAN | Batuhan BAŞPINAR | İlgin AKBIYIK | Burak Yasin AKTAŞ | Deniz YÜCE | Mustafa ERMAN | Kadir Mutlu HAYRAN

Yayıncı: TUBITAK

Dergi: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.826-831

Belge Tipi: Makale

Yayın Tarihi: 5/2019

Belge Dili: İngilizce

Document ID (Org No.): 2000750106

Sıklık: İki Aylık

eISSN: 1303-6165

pISSN: 1300-0144

Sayı

Yazarlar:

Deniz Can GÜVEN | Ömer DİZDAR | Abdullah Cevdet AKMAN | Ayşe Ezel BERKER | Emre YEKEDÜZ | Furkan CEYLAN | Batuhan BAŞPINAR | İlgin AKBIYIK | Burak Yasin AKTAŞ | Deniz YÜCE | Mustafa ERMAN | Kadir Mutlu HAYRAN

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 3, pp.826-831

Belge Tipi:

Makale

Yayın Tarihi:

5/2019

Belge Dili:

İngilizce

Document ID (Org No.):

2000750106

Sıklık:

İki Aylık

eISSN:

1303-6165

pISSN:

1300-0144