Melatonin as a stabilizer of mitochondrial function: role in diseases and aging

Cristina CARRASCO; Ana B. RODRIGUEZ; Jose A. PARIENTE

Makale detayları

Melatonin as a stabilizer of mitochondrial function: role in diseases and aging

Yazarlar:

Cristina CARRASCO | Ana B. RODRIGUEZ | Jose A. PARIENTE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 6, pp.822-831

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811801

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Anahtar kelimeler:

Özet:

 

It is now almost 60 years since the discovery of melatonin and new physiological functions of the indole continuously appear in the most recent studies worldwide. Experimental evidence emphasizes its importance as a stabilizer of the mitochondrial bioenergetics, which could be related to the prevention of development of aging and several diseases. In the next years, conscientious investigation about this topic should be undertaken by scientists of different research areas to achieve a better understanding of the molecular mechanisms implied. This will ultimately allow the development and clinical application of efficacious treatments.

 

It is now almost 60 years since the discovery of melatonin and new physiological functions of the indole continuously appear in the most recent studies worldwide. Experimental evidence emphasizes its importance as a stabilizer of the mitochondrial bioenergetics, which could be related to the prevention of development of aging and several diseases. In the next years, conscientious investigation about this topic should be undertaken by scientists of different research areas to achieve a better understanding of the molecular mechanisms implied. This will ultimately allow the development and clinical application of efficacious treatments.

Makale detayları

Melatonin as a stabilizer of mitochondrial function: role in diseases and aging

Yazarlar:

Cristina CARRASCO | Ana B. RODRIGUEZ | Jose A. PARIENTE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 6, pp.822-831

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811801

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152

Melatonin

mitochondria

diseases

aging

Alzheimer and Parkinson diseases

Sayı

Makale detayları

Melatonin as a stabilizer of mitochondrial function: role in diseases and aging

Yazarlar: Cristina CARRASCO | Ana B. RODRIGUEZ | Jose A. PARIENTE

Yayıncı: TUBITAK

Dergi: Turkish Journal of Biology 2015 Vol.39 Issue 6, pp.822-831

Belge Tipi: Makale

Yayın Tarihi: 12/2015

Belge Dili: Türkçe

Document ID (Org No.): 2000811801

Sıklık: İki Aylık

eISSN: 1303-6092

pISSN: 1300-0152

Melatonin

mitochondria

diseases

aging

Alzheimer and Parkinson diseases

Sayı

Yazarlar:

Cristina CARRASCO | Ana B. RODRIGUEZ | Jose A. PARIENTE

Yayıncı:

TUBITAK

Dergi:

Turkish Journal of Biology 2015 Vol.39 Issue 6, pp.822-831

Belge Tipi:

Makale

Yayın Tarihi:

12/2015

Belge Dili:

Türkçe

Document ID (Org No.):

2000811801

Sıklık:

İki Aylık

eISSN:

1303-6092

pISSN:

1300-0152